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The use of oxybutynin for treating axillary hyperhidrosis.

Abstract：

BACKGROUND:To evaluate the effectiveness and patient satisfaction with the use of oxybutynin for treating axillary hyperhidrosis in a large series of patients. METHODS:One hundred two patients with axillary hyperhidrosis were treated with oxybutynin. During the first week, patients received 2.5 mg of oxybutynin once a day in the evening. From the 8th to the 42nd day, they received 2.5 mg twice a day, and from the 43rd day to the end of the 12th week, they received 5 mg twice a day. All of the patients underwent two evaluations: before and after (12 weeks) the oxybutynin treatment, using a clinical questionnaire; and a clinical protocol for quality of life (QOL). RESULTS:More than 80% of the patients experienced an improvement in axillary hyperhidrosis; 36.3% of them presented a great improvement, and half of the patients showed improvements at all hyperhidrosis sites. Most of the patients showed improvements in the QOL (67.5%). The patients with very poor QOL before the treatment presented greater satisfaction levels after treatment. The side effects were minor, dry mouth being the most frequent (73.5%). CONCLUSIONS:Oxybutynin is a good alternative to sympathectomy. It presents good results and improves QOL without the side effects of sympathectomy.

journal_name

Ann Vasc Surg

journal_title

Annals of vascular surgery

authors

Wolosker N,de Campos JR,Kauffman P,Neves S,Munia MA,BiscegliJatene F,Puech-Leão P

doi

10.1016/j.avsg.2011.06.007

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

1057-62

issue

8

eissn

0890-5096

issn

1615-5947

pii

S0890-5096(11)00391-8

journal_volume

25

pub_type

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