Potential risk of zoonotic transmission from young swine to human: seroepidemiological and genetic characterization of hepatitis E virus in human and various animals in Beijing, China.

abstract：:Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear receptor that regulates gene expression of inflammatory mediators in liver injury. Hepatitis B virus (HBV) suppresses the PPAR gamma-mediated transactivation in liver cancerous cell lines. However, the role of PPAR gamma in patients with chroni...

journal_title：Journal of viral hepatitis

authors： Zhao Q,Fan YC,Zhao J,Gao S,Zhao ZH,Wang K

更新日期：2013-06-01 00:00:00

abstract：:We describe the epidemiology of hepatitis B virus (HBV) infection among women of reproductive age residing in areas of China that are highly endemic for chronic HBV, and provide evidence useful for decision-makers to guide strategies for preventing mother-to-child transmission of HBV, and assess the impact of perinata...

journal_title：Journal of viral hepatitis

authors： Zheng H,Cui FQ,Wang FZ,Huang LF,Shao XP,Du JF,Li J,Zhou Y,Zheng HZ,Zhuo JT,Zeng XX,Zhang GM,Miao N,Sun XJ,Liang XF,Luo HM

更新日期：2018-01-01 00:00:00

abstract：:The study aimed to assess whether caesarean section and nonbreastfeeding can prevent mother-to-child transmission (MTCT) in HBsAg- and HBeAg-positive mothers via a cohort study and a meta-analysis. (1) Pregnant women who were positive for HBsAg and HBeAg and did not receive antiviral treatment during pregnancy were re...

journal_title：Journal of viral hepatitis

authors： Pan YC,Jia ZF,Wang YQ,Yang N,Liu JX,Zhai XJ,Song Y,Wang C,Li J,Jiang J

更新日期：2020-10-01 00:00:00

abstract：:Primary or secondary failure of adefovir dipivoxil (ADV) therapy of chronic hepatitis B is not infrequent. The reasons for suboptimal responses are not well defined. In HIV and hepatitis C virus infection, failure of antiviral drug therapy has been linked with low blood drug levels. We have studied 20 well-defined pat...

journal_title：Journal of viral hepatitis

authors： Deterding K,Naesens L,Buti M,Janssen H,Kirschner J,Guerrero A,Reijnders J,Neyts J,Zoulim F,Wedemeyer H

更新日期：2011-07-01 00:00:00

abstract：:Patients with chronic hepatitis B (HBsAg-positive) are at risk of viral reactivation if rituximab is administered without antiviral treatment, a potentially fatal complication of treatment. Patients with so-called 'resolved hepatitis B virus infection' (HBsAg-negative/cAb-positive) may also be at risk. We performed a ...

journal_title：Journal of viral hepatitis

authors： Mozessohn L,Chan KK,Feld JJ,Hicks LK

更新日期：2015-10-01 00:00:00

abstract：:Interferon-alpha 2b (IFN-alpha 2b) can exert antiproliferative activity in both normal and malignant liver tissue. To study mechanisms of its antiproliferative action, the activity of the enzymes of adenosine metabolism were investigated. We studied 5'-nucleotidase (an adenosine-producing enzyme) and adenosine deamina...

journal_title：Journal of viral hepatitis

authors： Kocić G,Kocić R,Vlahović P,Pavlović D,Jevtović T

更新日期：1998-09-01 00:00:00

abstract：:Although tattooing is recognized as a risk factor for transmission of hepatitis C, the efficiency with which transmission occurs is unknown. Sera stored from a serosurvey of tattooists undertaken in 1984 to test for human immunodeficiency virus (HIV) provided the opportunity to determine the prevalence of serological ...

journal_title：Journal of viral hepatitis

authors： Thompson SC,Goudey RE,Breschkin AM,Carnie J,Catton M

更新日期：1997-03-01 00:00:00

abstract：:We evaluated the effect of sustained virologic response (SVR) from direct-acting antiviral (DAA)- and interferon-based treatments on hepatocellular carcinoma (HCC) risk in a large population-based cohort in Canada. We used data from the BC Hepatitis Testers Cohort, which includes ~1.3 million individuals tested for HC...

journal_title：Journal of viral hepatitis

authors： Janjua NZ,Wong S,Darvishian M,Butt ZA,Yu A,Binka M,Alvarez M,Woods R,Yoshida EM,Ramji A,Feld J,Krajden M

更新日期：2020-08-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a variable RNA virus that can readily establish persistent infection. Cellular immune responses are important in the early control of the virus. Evidence from animal models suggests that mutation in epitopes recognized by CD8+ T lymphocytes may play an important role in the establishment of ...

journal_title：Journal of viral hepatitis

authors： Komatsu H,Lauer G,Pybus OG,Ouchi K,Wong D,Ward S,Walker B,Klenerman P

更新日期：2006-02-01 00:00:00

abstract：:The Andaman and Nicobar Islands, Union Territory of India, are home to six primitive tribes. Studies carried out earlier among these tribes revealed very high rates of hepatitis B infection. We have now studied hepatitis A and E infection among them. A total of 951 serum samples were collected from four accessible tri...

journal_title：Journal of viral hepatitis

authors： Murhekar MV,Sehgal SC,Murhekar KM,Padbhidri SP,Chitambar SD,Arankalle VA

更新日期：2002-07-01 00:00:00

abstract：:People who use drugs are a key population in global HCV control. We evaluated the efficacy of an innovative model to eliminate HCV infection in a high-risk population of PWUD in a service for substance use disorder (SUD). Between January 2018 and December 2018, we conducted a prospective, interventional, before and af...

journal_title：Journal of viral hepatitis

authors： Messina V,Russo A,Parente E,Russo G,Raimondo T,Salzillo A,Simeone F,Onorato L,Di Caprio G,Pisaturo M,Coppola N

更新日期：2020-12-01 00:00:00

abstract：:Peripheral blood mononuclear cells (PBMC) from chronic hepatitis C virus-infected persons can harbour viral variants that are not detected in plasma samples. We explored the presence and persistence of HCV genotypes in plasma and PBMC cultures from 25 HCV-monoinfected and 25 HIV/HCV-coinfected patients with haemophili...

journal_title：Journal of viral hepatitis

authors： Parodi C,García G,Monzani MC,Culasso A,Aloisi N,Corti M,Campos R,de E de Bracco MM,Baré P

更新日期：2015-07-01 00:00:00

abstract：:High-dose induction with alpha-interferon induces early viral clearance of hepatitis C and combined with ribavirin enhances sustained response. We assess whether adding ribavirin after viral clearance obtained by alpha-interferon induction increased the rate of viral eradication.Forty-one naïve patients with chronic h...

journal_title：Journal of viral hepatitis

authors： Di Marco V,Ferraro D,Almasio P,Vaccaro A,Parisi P,Cappello M,Cino N,Di Stefano R,Craxì A

更新日期：2002-09-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most common complication of HCV infection leading to liver transplantation. We evaluated the impact of aetiology of liver disease on patient and graft survival following liver transplantation for HCC. From the Scientific Registry of Transplant Recipients (2002-2011), all adults wh...

journal_title：Journal of viral hepatitis

authors： Younossi ZM,Stepanova M,Saab S,Ahmed A,Lam B,Srishord M,Venkatesan C,Wai H,Henry L

更新日期：2016-01-01 00:00:00

abstract：:In a previously reported randomized controlled trial of interferon-alpha (IFN-alpha) for chronic hepatitis B, we found a significant difference in response between Chinese adults with elevated vs normal pretreatment aminotransferase (ALT) levels. The aim of this study was to determine the correlation between serum hep...

journal_title：Journal of viral hepatitis

authors： Lok AS,Ghany MG,Watson G,Ayola B

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND AIMS:New therapies for HCV are rapidly emerging and providers are advising select patients to defer treatment and elect 'watchful waiting'. During the watchful waiting period, patients have been shown to have high rates of illness uncertainty and depression. We sought to answer the question of whether re...

journal_title：Journal of viral hepatitis

authors： Colagreco JP,Bailey DE,Fitzpatrick JJ,Musil CM,Afdhal NH,Lai M

更新日期：2014-10-01 00:00:00

abstract：AIM:Elevated body mass index (BMI) in chronic hepatitis C (CHC) has been associated with reduced rates of sustained virological response (SVR). The aims of this study were to determine whether early viral kinetics (and subsequently SVR) are influenced by weight or BMI by measuring HCV RNA at week 4 using two PCR assays...

journal_title：Journal of viral hepatitis

authors： Pattullo V,Ravindran NC,Mazzulli T,Wong DK,Heathcote EJ

更新日期：2010-12-01 00:00:00

abstract：:Long-term functional outcomes of sofosbuvir-based antiviral treatment were evaluated in a cohort study involving 16 Italian centres within the international compassionate use programme for post-transplant hepatitis C virus (HCV) recurrence. Seventy-three patients with cirrhosis (n=52) or fibrosing cholestatic hepatiti...

journal_title：Journal of viral hepatitis

authors： Vukotic R,Conti F,Fagiuoli S,Morelli MC,Pasulo L,Colpani M,Foschi FG,Berardi S,Pianta P,Mangano M,Donato MF,Malinverno F,Monico S,Tamè M,Mazzella G,Belli LS,Viganò R,Carrai P,Burra P,Russo FP,Lenci I,Toniutto P

更新日期：2017-10-01 00:00:00

abstract：:Transient elastography (TE) is the reference method to obtain liver stiffness measurements (LSM), but no results are obtained in 3.1% and unreliable in 15.8%. We assessed the applicability and diagnostic accuracy of TE re-evaluation using M and XL probes. From March 2011 to April 2012 868 LSM were performed with the M...

journal_title：Journal of viral hepatitis

authors： Carrión JA,Puigvehí M,Coll S,Garcia-Retortillo M,Cañete N,Fernández R,Márquez C,Giménez MD,Garcia M,Bory F,Solà R

更新日期：2015-03-01 00:00:00

abstract：:The ECHO model was developed to expand access to medical care for populations with HCV infection in underserved areas. We aimed to compare HCV treatment outcomes in community-based clinics with the Austral University Hospital (AUH) and to assess improvement in physician knowledge and skills. In October 2015, we establ...

journal_title：Journal of viral hepatitis

authors： Mendizabal M,Ridruejo E,Ceballos S,Sixto M,Billordo A,Gadea C,Mengarelli S,Alonso C,Palazzo A,De María L,Bruno A,Perez D,Piñero F,Deltrozzo V,Mendoza C,Figueroa S,Manero E,Villa M,Barreyro F,Moreno V,Vilar J,Mur

更新日期：2019-11-01 00:00:00

abstract：:Hepatitis A incidence has declined in most countries through a combination of prevention measures, augmented through the use of a highly effective vaccine. In Australia, the proportion of the population susceptible to hepatitis A infection has declined over time due to high rates of opportunistic vaccination as well a...

journal_title：Journal of viral hepatitis

authors： Jayasundara D,Hui BB,Regan DG,Heywood AE,MacIntyre CR,Wood JG

更新日期：2019-01-01 00:00:00

abstract：:In 1996, a combined vaccine against both hepatitis A and B was licensed and commercialized and has been recommended for healthcare personnel in Belgium. This study compares the immunogenicity against hepatitis B virus (HBV) and safety of two vaccination schedules (0-1-12 months and 0-1-6 months) with this vaccine. Thi...

journal_title：Journal of viral hepatitis

authors： De Schryver A,Verstrepen K,Vandersmissen L,Vandermeeren N,Vernaillen I,Vranckx R,Van Damme P,van Sprundel M

更新日期：2011-04-01 00:00:00

abstract：:In Italy, HDV infection endemicity has greatly decreased overtime. Migratory flow may change this scenario as migrants often come from high HDV endemicity areas. Here, we studied characteristics of HDV infection in Italy, particularly addressed to the birth area of subjects. Chronic HBsAg carriers consecutively referr...

journal_title：Journal of viral hepatitis

authors： Stroffolini T,Ciancio A,Furlan C,Vinci M,Fontana R,Russello M,Colloredo G,Morisco F,Coppola N,Babudieri S,Ferrigno L,Sagnelli C,Sagnelli E

更新日期：2020-09-01 00:00:00

abstract：:In this pilot study, we evaluated the efficacy of interferon-alpha (IFN) plus Thymosin-alpha 1 (TA1) to that of IFN alone in naive patients with chronic hepatitis C. Twenty-two patients were randomized to receive interferon-alpha 2b (3 million units three times a week) plus thymosin-alpha l (900 microg/m2 body surface...

journal_title：Journal of viral hepatitis

authors： Andreone P,Gramenzi A,Cursaro C,Felline F,Loggi E,D'Errico A,Spinosa M,Lorenzini S,Biselli M,Bernardi M

更新日期：2004-01-01 00:00:00

abstract：:To assess the prevalence of hepatitis delta virus (H delta V) in northern India, 204 adult patients with acute and chronic liver disease who were positive for hepatitis B virus (HBV) markers were screened for anti-H delta V antibody by enzyme-linked immunosorbent assay (ELISA). Anti-H delta V antibodies were positive ...

journal_title：Journal of viral hepatitis

authors： Singh V,Goenka MK,Bhasin DK,Kochhar R,Singh K

更新日期：1995-01-01 00:00:00

abstract：:Infection with the hepatitis C virus (HCV) remains chronic in 75% of infected individuals, in whom it can cause liver inflammation and progressive fibrosis leading to cirrhosis in 20% of patients. A sustained viral response (SVR) to HCV therapy, i.e. undetectable plasma HCV RNA 6 months after the end of treatment, lea...

journal_title：Journal of viral hepatitis

authors： Bräu N

更新日期：2004-05-01 00:00:00

abstract：:Hepatitis A virus (HAV) infection is still an important issue worldwide. A distinct set of viruses encode proteins that enhance viral cap-independent translation initiation driven by an internal ribosome entry site (IRES) and suppress cap-dependent host translation. Unlike cytolytic picornaviruses, replication of HAV ...

journal_title：Journal of viral hepatitis

authors： Kanda T,Gauss-Müller V,Cordes S,Tamura R,Okitsu K,Shuang W,Nakamoto S,Fujiwara K,Imazeki F,Yokosuka O

更新日期：2010-09-01 00:00:00

abstract：:The availability of effective, simple, well-tolerated oral direct-acting antiviral (DAA) hepatitis C regimens has raised optimism for hepatitis C virus (HCV) elimination at the population level. HCV reinfection in key populations such as people who inject drugs (PWID) and HIV-infected men who have sex with men (MSM) h...

journal_title：Journal of viral hepatitis

authors： Falade-Nwulia O,Sulkowski MS,Merkow A,Latkin C,Mehta SH

更新日期：2018-03-01 00:00:00

abstract：:The treatment of hepatitis C is expensive, difficult and arduous from the patient's perspective. It is similarly difficult for the clinician to decide who and when to treat. If hepatitis C is viewed from the liver's perspective we need only treat those patients who will develop the complications of chronic liver disea...

journal_title：Journal of viral hepatitis

authors： Dillon JF

更新日期：2004-09-01 00:00:00

abstract：:Quantitative serology for hepatitis B surface antigen (HBsAg) is a new candidate marker for prediction of clinical outcome. The aim of this study was to investigate the clinical significance of quantifying HBsAg in patients with hepatitis B virus (HBV) infection. A total of 424 patients who tested positive for HBsAg a...

journal_title：Journal of viral hepatitis

authors： Togo S,Arai M,Tawada A,Chiba T,Kanda T,Fujiwara K,Imazeki F,Yokosuka O

更新日期：2011-10-01 00:00:00