Propofol sedation after open heart surgery. A clinical and pharmacokinetic study.

abstract：:We have studied the respiratory effects of 5 and 10 cmH2O pressure support ventilation during anaesthesia with 1.5% end-tidal concentration of isoflurane in nine healthy, spontaneously breathing, adult patients. Some of the patients demonstrated an irregular respiratory pattern with periods of apnoea and we therefore ...

journal_title：Anaesthesia

authors： Bhatt SB,Chui PT,Gin T,Tam YH,Oh TE

更新日期：1995-12-01 00:00:00

abstract：:The preferences of 118 elderly patients, aged from 70 to 97 years, concerning the institution of artificial ventilation in the event of an overwhelming illness, were investigated using a questionnaire. Most patients wanted treatment if the outcome was likely to be good, but in approximately half, the desire for treatm...

journal_title：Anaesthesia

authors： Heap MJ,Munglani R,Klinck JR,Males AG

更新日期：1993-12-01 00:00:00

abstract：:A 74-year-old man presenting for aortic reconstructive surgery showed severe, previously undiagnosed obstructive sleep apnoea during overnight oximetry monitoring before operation. Postoperatively, in the first 4 hours following extubation, he suffered 238 episodes of respiratory obstruction. These events were associa...

journal_title：Anaesthesia

authors： Reeder MK,Goldman MD,Loh L,Muir AD,Casey KR,Gitlin DA

更新日期：1991-10-01 00:00:00

abstract：:Propofol has been shown to cause pain on injection. This study investigated the effect of warming propofol to 37 degrees C on the pain of intravenous injection. One hundred and one women on outpatient gynaecology lists were allocated to receive propofol either at room temperature or at 37 degrees C. Warming propofol d...

journal_title：Anaesthesia

authors： Fletcher GC,Gillespie JA,Davidson JA

更新日期：1996-05-01 00:00:00

abstract：:A technique is described for the determination of equipotent rates of infusion of intravenous hypnotic agents. Two end points have been defined; the rates needed to suppress the initial response to the surgical incision in 50% (ED50) and 95% (ED95) of patients receiving continuous infusion anaesthesia to supplement 67...

journal_title：Anaesthesia

authors： Sear JW,Phillips KC,Andrews CJ,Prys-Roberts C

更新日期：1983-10-01 00:00:00

abstract：:The haemostatic management of major obstetric haemorrhage remains challenging, and current published guidance relies heavily on experience from the non-pregnant population and expert opinion. In recent years, an interest in the implications of relative hypofibrinogenaemia, point-of-care monitoring of coagulation abnor...

journal_title：Anaesthesia

authors： Collis RE,Collins PW

更新日期：2015-01-01 00:00:00

abstract：:This study evaluated the ability of prehospital providers who had no previous training in intubation, to use an Airtraq laryngoscope to intubate a manikin model of a Cormack and Lehane grade III/IV view. Volunteers attending the Australian College of Ambulance Professionals conference, Adelaide, in November 2006 recei...

journal_title：Anaesthesia

authors： Woollard M,Mannion W,Lighton D,Johns I,O'meara P,Cotton C,Smyth M

更新日期：2007-10-01 00:00:00

abstract：:A high frequency oscillator and its interface with the Siemens 900C ventilator form a combined high frequency oscillator and intermittent positive pressure ventilator. This combined high frequency ventilator is designed for use in selected cases of refractory hypoxaemia. ...

journal_title：Anaesthesia

authors： Raphael JH,Atkinson I,Bexton MD

更新日期：1995-07-01 00:00:00

abstract：:A newly designed 4 FG double-lumen catheter with the second port located either 5 or 7 cm proximal to the tip was tested in five children undergoing open heart surgery. The catheter was inserted percutaneously and initially positioned in the superior vena cava, right atrium or inferior vena cava. During cardiopulmonar...

journal_title：Anaesthesia

authors： Fukutome T,Kohjiro M,Sese A,Ueno Y

更新日期：1993-05-01 00:00:00

abstract：:Among 25 patients undergoing cardiac surgery with the aid of cardiopulmonary bypass, 13 who recovered uneventfully all had normal (less than 2 mg/litre) levels of serum C-reactive protein pre-operatively. In contrast, 10 of the 12 patients who suffered from various postoperative complications, including two who died, ...

journal_title：Anaesthesia

authors： Boralessa H,de Beer FC,Manchie A,Whitwam JG,Pepys MB

更新日期：1986-01-01 00:00:00

abstract：:The effects of anticholinergic premedication with 1.0 mg atropine, 0.5 mg hyoscine and 0.2 mg glycopyrronium on volume and pH of gastric contents were studied and compared with a group receiving no anticholinergic premedication. The antisialogogue effects were also compared. Though the groups receiving atropine and gl...

journal_title：Anaesthesia

authors： Mirakhur RK,Reid J,Elliott J

更新日期：1979-05-01 00:00:00

abstract：:Increasing the calculated plasma concentration of propofol has been shown to increase choice reaction time and visual and auditory response times. We studied the relationship of reaction to a vibrating handset as the effect-site target-controlled propofol concentration was incrementally increased in 20 patients during...

journal_title：Anaesthesia

authors： Anderson KJ,Allam S,Chapman R,Kenny GN

更新日期：2013-02-01 00:00:00

abstract：:A postal survey of all maternity units in the UK was conducted to gain information regarding the management of inadvertent dural taps occurring during the sitting of epidurals for pain relief in labour. Of the units surveyed only 58.5% had a written protocol for the management of dural taps. Following their occurrence...

journal_title：Anaesthesia

authors： Sajjad T,Ryan TD

更新日期：1995-02-01 00:00:00

abstract：:The elderly have the ethical and legal equivalence of younger adults, yet are treated differently by society. Numerous recent reports have exposed poor inpatient care resulting in part from institutional ageism, which has moral and legal implications for healthcare providers. Morally, there is an argument for positive...

journal_title：Anaesthesia

authors： White SM

更新日期：2014-01-01 00:00:00

abstract：:Thirty-six healthy patients, ASA 1, aged 16-41 years, scheduled for elective plastic surgery were studied to determine if thoracocervical or lumbar epidural blocks affected the lag time of the pulse oximeter response. Patients were allocated to receive thoracocervical epidural block (n = 20) (group 1) (lignocaine 1%) ...

journal_title：Anaesthesia

authors： Xue FS,Liao X,Tong SY,Liu QH,An G,Luo LK

更新日期：1996-12-01 00:00:00

abstract：:A double-blind, randomised clinical study was undertaken to compare the effect of temperature on the incidence and severity of the pain experienced on injection of propofol. The number of patients who experienced pain and the severity of the pain were reduced significantly when propofol was administered at a temperatu...

journal_title：Anaesthesia

authors： McCrirrick A,Hunter S

更新日期：1990-06-01 00:00:00

abstract：:We report the case of a 14-year-old girl who deliberately ingested 8-9 g of dapsone and presented with severe methaemoglobinaemia and altered mental status. Prompt treatment with repeated doses of methylene blue and organ support brought about control of the methaemoglobinaemia and averted organ failure. ...

journal_title：Anaesthesia

authors： Ferguson AJ,Lavery GG

更新日期：1997-04-01 00:00:00

abstract：:A multicentre trial of the use of the intubating laryngeal mask was carried out at seven centres in the United Kingdom using the same agreed protocol. Lung ventilation followed by blind tracheal intubation through the intubating laryngeal mask was attempted on 500 ASA grade 1 and 2 patients. It was possible to insert ...

journal_title：Anaesthesia

authors： Baskett PJ,Parr MJ,Nolan JP

更新日期：1998-12-01 00:00:00

abstract：:A prospective trial was designed to assess the effectiveness of three different concentrations of bupivacaine (Marcain) for use in obstetric epidural analgesia. The purpose of the study was to see if reduction of the concentration of bupivacaine to 0.125% would reduce the total dose of the drug given without reducing ...

journal_title：Anaesthesia

authors： Stainthorp SF,Bradshaw EG,Challen PD,Tobias MA

更新日期：1978-01-01 00:00:00

abstract：:Viral gastroenteritis is usually a mild, self-limiting illness. We report a case of a previously well 74-year-old woman who suffered a grave complication of this common condition, and caused a significant outbreak of illness amongst staff involved in her care. This case highlights the risks of Hospital Acquired Infect...

journal_title：Anaesthesia

authors： Appelboam R,Hammond E

更新日期：2004-03-01 00:00:00

abstract：:Pregnanolone emulsion, a new steroid anaesthetic agent, was administered intravenously as bolus doses to six young healthy male volunteers in a preliminary pharmacokinetic and pharmacodynamic study. The plasma concentration-time curves fitted a two-compartment model. The elimination half-life was between 0.9 and 1.4 h...

journal_title：Anaesthesia

authors： Carl P,Høgskilde S,Nielsen JW,Sørensen MB,Lindholm M,Karlen B,Bäckstrøm T

更新日期：1990-03-01 00:00:00

abstract：:Anaesthetists require a good knowledge of the excretion of drugs in breast milk and the potential hazards to suckling infants of drug ingestion via breast milk. A brief account of the physiology of lactation is given. The mechanisms of drug passage into breast milk are discussed followed by a review of the excretion i...

journal_title：Anaesthesia

authors： Lee JJ,Rubin AP

更新日期：1993-07-01 00:00:00

abstract：:Difficult airway practice guidelines include the use of a supraglottic airway device as part of the armamentarium to provide and maintain ventilation and oxygenation. We retrospectively reviewed 14 480 patients aged ≥ 18 years who underwent general anaesthesia. We identified 74 (0.5%) patients whose lungs were identif...

journal_title：Anaesthesia

authors： Saito T,Liu W,Chew ST,Ti LK

更新日期：2015-09-01 00:00:00

abstract：:We assessed conditions for insertion of a laryngeal mask airway in 90 unpremedicated adult patients who received either thiopentone 5 mg.kg-1 preceded by 40 mg of topical lignocaine spray to the posterior pharyngeal wall or propofol 2.5 mg.kg-1 alone in a randomised, single-blinded trial. All patients received fentany...

journal_title：Anaesthesia

authors： Seavell CR,Cook TM,Cox CM

更新日期：1996-07-01 00:00:00

abstract：:Intravenous morphine and diamorphine are routinely used for postoperative analgesia but the relative histamine releasing abilities of these drugs have not been compared in man. Thirty-eight patients were randomly allocated to receive morphine (0.16 mg.kg-1) or diamorphine (0.08 mg.kg-1) after abdominal surgery. Blood ...

journal_title：Anaesthesia

authors： Withington DE,Patrick JA,Reynolds F

更新日期：1993-01-01 00:00:00

abstract：:A decision by a society to sanction assisted dying in any form should logically go hand-in-hand with defining the acceptable method(s). Assisted dying is legal in several countries and we have reviewed the methods commonly used, contrasting these with an analysis of capital punishment in the USA. We expected that, sin...

journal_title：Anaesthesia

authors： Sinmyee S,Pandit VJ,Pascual JM,Dahan A,Heidegger T,Kreienbühl G,Lubarsky DA,Pandit JJ

更新日期：2019-05-01 00:00:00

abstract：:We present a patient who suffered two episodes of torsade de pointes ventricular tachycardia during general anaesthesia for abdominal surgery. The first occurred on suctioning of the tracheobronchial tree and the second while anaesthesia was light. Since ST segment elevation was in each case noted before the onset of ...

journal_title：Anaesthesia

authors： Mizutani K,Toyoda Y,Kubota H

更新日期：1996-09-01 00:00:00

abstract：:An internal jugular catheter, which was inserted into a patient with a traumatic haemopneumothorax, accidentally entered the pleural cavity. This was initially undetected because the two signs most frequently used to confirm correct placement, those of blood reflux and fluctuation of central venous pressure with respi...

journal_title：Anaesthesia

authors： Pina J,Morujão N,Castro-Tavares J

更新日期：1992-01-01 00:00:00

abstract：:This study compared the analgesic efficacy of an epidural infusion of ropivacaine and ropivacaine with sufentanil following major knee surgery. In a double-blind clinical trial, 115 adult patients received either epidural ropivacaine (R group, 2 mg.ml(-1)), or ropivacaine (2 mg.ml(-1)) with sufentanil (RS group, 1 mic...

journal_title：Anaesthesia

authors： Lorenzini C,Moreira LB,Ferreira MB

更新日期：2002-05-01 00:00:00

abstract：:Two anaesthetic procedures that did not include nitrous oxide were compared in a randomised study of 50 patients for tympanoplasty and tympanoscopy: propofol given for induction and maintenance, and thiopentone-isoflurane given for induction and maintenance, respectively. Induction in the first group was with a bolus ...

journal_title：Anaesthesia

authors： Ledderose H,Rester P,Carlsson P,Peter K

更新日期：1988-03-01 00:00:00