A P5 cancer medicine approach: why personalized medicine cannot ignore psychology.

Abstract:

:A system approach termed P4 medicine has recently been proposed in the field of oncology. This approach has been advanced as an extension of what is usually called 'personalized' or 'genomic medicine'. P4 medicine creates effective predictive, personalized, preventive and participatory models to treat patients. In order to give more relevance to the behavioural component that impinges on the way individuals act to prevent, cope and react to illnesses, how they decide between different therapeutic options and interact with physicians and adhere to treatment, we propose that P4 medicine should be transformed into P5 medicine. The fifth P represents the psycho-cognitive aspects to be considered in order to empower the patient, increase his/her quality of life and transform him/her from a passive recipient into an active decision-maker in the treatment process.

journal_name

J Eval Clin Pract

authors

Pravettoni G,Gorini A

doi

10.1111/j.1365-2753.2011.01709.x

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

594-6

issue

4

eissn

1356-1294

issn

1365-2753

journal_volume

17

pub_type

杂志文章
  • Beyond checkboxes: A qualitative assessment of physicians' experiences providing care in a patient-centred medical home.

    abstract:RATIONALE, AIMS, AND OBJECTIVES:The patient-centred medical home (PCMH) is an innovative approach to health care reform. Despite a well-established process for recognizing PCMH practices, fidelity to, and/or adaptation of, the PCMH model can limit health care and population health improvements. This study explored the ...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/jep.13136

    authors: Sklar M,Seijo C,Goldman RE,Eaton CB

    更新日期:2019-12-01 00:00:00

  • Are performance indicators generic? The international experience of the Quality Indicator Project.

    abstract::Performance indicators for healthcare organizations represent a strategy for accountability worldwide. A universal approach to either the design for indicators or their applicability to local needs remains a work in progress. The Maryland Hospital Association's Quality Indicator Project (QIP) is the only indicator-bas...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1046/j.1365-2753.2003.00374.x

    authors: Kazandjian VA,Matthes N,Wicker KG

    更新日期:2003-05-01 00:00:00

  • Effects of an educational patient safety campaign on patients' safety behaviours and adverse events.

    abstract::Rationale, aims and objectives  The study aims to investigate the effects of a patient safety advisory on patients' risk perceptions, perceived behavioural control, performance of safety behaviours and experience of adverse incidents. Method  Quasi-experimental intervention study with non-equivalent group comparison w...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1365-2753.2012.01820.x

    authors: Schwappach DL,Frank O,Buschmann U,Babst R

    更新日期:2013-04-01 00:00:00

  • Improving perinatal Group B streptococcus screening with process indicators.

    abstract:RATIONALE:Group B streptococcus (GBS) neonatal infection can be prevented by screening pregnant women for GBS colonization from the 34th to the 38th week of gestation, as has been recommended in France since 2001. We assessed guideline adherence among midwives and obstetricians. METHODS:From 2006 to 2008, new and mand...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1365-2753.2011.01658.x

    authors: Albouy-Llaty M,Nadeau C,Descombes E,Pierre F,Migeot V

    更新日期:2012-08-01 00:00:00

  • Reasoning, evidence, and clinical decision-making: The great debate moves forward.

    abstract::When the editorial to the first philosophy thematic edition of this journal was published in 2010, critical questioning of underlying assumptions, regarding such crucial issues as clinical decision making, practical reasoning, and the nature of evidence in health care, was still derided by some prominent contributors ...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 社论

    doi:10.1111/jep.12831

    authors: Loughlin M,Bluhm R,Buetow S,Borgerson K,Fuller J

    更新日期:2017-10-01 00:00:00

  • Characteristics of shared decision making in Romania from the patient perspective: A cross-sectional multicentric study.

    abstract:BACKGROUND:Shared decision making (SDM) is very important from patients' perspective. This process has not yet been evaluated in Romania. The study aims to evaluate SDM from the patients' perspective and to evaluate patients' characteristics that associate with SDM. MATERIAL AND METHODS:A cross-sectional multicentric ...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章,多中心研究

    doi:10.1111/jep.13257

    authors: Baicus C,Balanescu P,Zeh S,Oprisan E,Lapadatu R,Gurghean A,Padureanu V,Rezus C,Mitu F,Jurcut R,Balanescu AR,Daha I,Balanescu E,Bojinca M,Pinte L,Constantin AM,Dima N,Floria M,Leon-Constantin MM,Roca M,Mitu M,Chi

    更新日期:2019-12-01 00:00:00

  • Primary care providers perform more neurologic visits than neurologists among Medicare beneficiaries.

    abstract:RATIONALE, AIMS AND OBJECTIVES:Little is known about which medical providers, other than neurologists, are involved in the care of neurologic conditions. We aimed to describe the current distribution of outpatient neurologic care by provider type. METHODS:We conducted a restrospective, cross-sectional analysis using a...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/jep.13439

    authors: Lin CC,Hill CE,Burke JF,Kerber KA,Hartley SE,Callaghan BC,Skolarus LE

    更新日期:2020-08-04 00:00:00

  • Effect of short-term intensive insulin therapy on quality of life in type 2 diabetes.

    abstract:RATIONALE, AIMS AND OBJECTIVES:Short-term intensive insulin therapy (IIT) early in the course of type 2 diabetes can improve pancreatic beta-cell function and even induce normoglycemia that persists post-therapy. In spite of this benefit, insulin is often delayed until late in the course of disease partly because of it...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1365-2753.2010.01552.x

    authors: Opsteen C,Qi Y,Zinman B,Retnakaran R

    更新日期:2012-04-01 00:00:00

  • Evidence-based medicine training in a resource-poor country, the importance of leveraging personal and institutional relationships.

    abstract:RATIONALE, AIMS AND OBJECTIVES:Efforts to implement evidence-based medicine (EBM) training in developing countries are limited. We describe the results of an international effort to improve research capacity in a developing country; we conducted a course aimed at improving basic EBM attitudes and identified challenges....

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1365-2753.2011.01635.x

    authors: Tomatis C,Taramona C,Rizo-Patrón E,Hernández F,Rodríguez P,Piscoya A,Gonzales E,Gotuzzo E,Heudebert G,Centor RM,Estrada CA

    更新日期:2011-08-01 00:00:00

  • Therapist self-disclosure and the problem of shared-decision making.

    abstract::Therapist self-disclosure is one of the most controversial topics in the history of psychotherapy. The controversies reflect some basic discussions regarding the nature of psychotherapy practice. In psychotherapy practice, a particular concern is the interaction between the psychotherapist and the patient. The expert-...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/jep.13289

    authors: Berg H,Bjornestad J,Våpenstad EV,Davidson L,Binder PE

    更新日期:2020-04-01 00:00:00

  • Statin prescribing according to gender, age and indication: what about the benefit-risk balance?

    abstract:RATIONALES, AIMS AND OBJECTIVES:The increasing dispensing of statins has raised concern about the appropriateness of prescribing to various population groups. We aimed to (1) investigate incident and prevalent statin prescribing according to indication, gender and age and (2) relate prescribing patterns to evidence on ...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/jep.12462

    authors: Wallach-Kildemoes H,Stovring H,Holme Hansen E,Howse K,Pétursson H

    更新日期:2016-04-01 00:00:00

  • Thiele massage as a therapeutic option for women with chronic pelvic pain caused by tenderness of pelvic floor muscles.

    abstract:AIMS AND OBJECTIVES:Musculoskeletal system has been found to be involved in genesis and perpetuation of chronic pelvic pain (CPP) and has strong evidences that up to 80% of women with CPP present dysfunction of the musculoskeletal system. In this study, we report a series of women with CPP caused by tenderness of pelvi...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1365-2753.2009.01202.x

    authors: Montenegro ML,Mateus-Vasconcelos EC,Candido dos Reis FJ,Rosa e Silva JC,Nogueira AA,Poli Neto OB

    更新日期:2010-10-01 00:00:00

  • User involvement in clinical audit: a review of developments and issues of good practice.

    abstract::There have been considerable political and organizational moves to involve 'consumers' (patients, carers, service users, potential users, local communities and the public at large) in the provision, planning and monitoring of health services. Such developments beg the question 'what constitutes good practice in user i...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2753.1996.tb00034.x

    authors: Kelson M

    更新日期:1996-05-01 00:00:00

  • Adapting evidence-based clinical practice guidelines at university teaching hospitals: A model for the Eastern Mediterranean Region.

    abstract:RATIONALE, AIMS, AND OBJECTIVES:Clinical practice guidelines (CPGs) are significant tools for evidence-based health care quality improvement. The CPG program at King Saud University was launched as a quality improvement program to fulfil the international accreditation standards. This program was a collaboration betwee...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/jep.12927

    authors: Amer YS,Wahabi HA,Abou Elkheir MM,Bawazeer GA,Iqbal SM,Titi MA,Ekhzaimy A,Alswat KA,Alzeidan RA,Al-Ansary LA

    更新日期:2019-08-01 00:00:00

  • A return to reasonableness and virtue in medical epistemology.

    abstract::The foundationalist and anti-foundationalist conceptions of medical knowledge have been at loggerheads for decades. Evidence-based medicine (EBM), the most prominent form of foundationalism, has attained wide appeal and acceptance among authorities. It proposes that evidence is the "base" upon which all clinical decis...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/jep.13273

    authors: Ghinea N

    更新日期:2020-04-01 00:00:00

  • Is there life after evidence-based medicine?

    abstract::Recent years have witnessed the rising star of evidence-based medicine (EBM) as an approach towards rationalizing clinical practice in the face of an exponentially growing body of knowledge. Along with it, however, a sense of unease is rising among practising doctors, as they feel that well-intentioned principles may ...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1365-2753.2003.00473.x

    authors: Porta M

    更新日期:2004-05-01 00:00:00

  • An educational programme for peer review groups to improve treatment of chronic heart failure and diabetes mellitus type 2 in general practice.

    abstract:RATIONALE, AIMS AND OBJECTIVES:Peer review groups are considered helpful for quality improvement in primary care. An interactive educational programme for small peer groups was developed, focusing on the implementation of newly developed treatment guidelines. The aim is to evaluate the effect of the programme on adhere...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2753.2005.00625.x

    authors: Kasje WN,Denig P,Stewart RE,de Graeff PA,Haaijer-Ruskamp FM

    更新日期:2006-12-01 00:00:00

  • Tai chi for lowering resting blood pressure in the elderly: a systematic review.

    abstract:OBJECTIVES:To assess the evidence for tai chi in reducing resting blood pressure (BP) in the elderly. METHODS:Databases were searched up to February 2009. All randomized clinical trials (RCTs) testing the effects of tai chi on resting BP in the elderly were considered. The selection of studies, data extraction and val...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2753.2009.01210.x

    authors: Lee MS,Lee EN,Kim JI,Ernst E

    更新日期:2010-08-01 00:00:00

  • Values-based practice and phenomenological psychopathology: implications of existential changes in depression.

    abstract::Values-based practice (VBP), developed as a partner theory to evidence-based medicine (EBM), takes into explicit consideration patients' and clinicians' values, preferences, concerns and expectations during the clinical encounter in order to make decisions about proper interventions. VBP takes seriously the importance...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/jep.12313

    authors: Fernandez AV,Wieten S

    更新日期:2015-06-01 00:00:00

  • Obtaining the mean relative weights of the cost of care in Catalonia (Spain): retrospective application of the adjusted clinical groups case-mix system in primary health care.

    abstract:OBJECTIVE:The study aims to obtain the mean relative weights (MRWs) of the cost of care through the retrospective application of the adjusted clinical groups (ACGs) in several primary health care (PHC) centres in Catalonia (Spain) in routine clinical practice. METHODS:This is a retrospective study based on computerize...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1365-2753.2012.01818.x

    authors: Sicras-Mainar A,Velasco-Velasco S,Navarro-Artieda R,Aguado Jodar A,Plana-Ripoll O,Hermosilla-Pérez E,Bolibar-Ribas B,Prados-Torres A,Violan-Fors C

    更新日期:2013-04-01 00:00:00

  • In the eye of the beholder: problems of perception in designing a strategy to promote evidence-based clinical policy.

    abstract::Independent qualitative evaluation of a project designed to ensure that clinical policy in specific areas of care in three obstetric units within one English health district was based on authoritative evidence. Data from nonparticipant observation, interviews, questionnaires and documents were combined to generate a d...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1046/j.1365-2753.2000.00224.x

    authors: Humphrey C,Berrow D

    更新日期:2000-05-01 00:00:00

  • The effect of participation in a weight loss programme on short-term health resource utilization.

    abstract::Obese people consume significantly greater amounts of health resources. This study set out to determine if health resource utilization by obese people decreases after losing weight in a comprehensive medically supervised weight management programme. Four hundred and fifty-six patients enrolled in a single-centred, mul...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1046/j.1365-2753.2002.00320.x

    authors: van Walraven C,Dent R

    更新日期:2002-02-01 00:00:00

  • On understanding the self of the schizophrenics.

    abstract::Identified as a mental disorder by Emil Kraepelin and Eugen Bleuler (1858-1939), schizophrenia has been subject to various criticisms, on both political and scientific grounds. Still, until the latest edition of the Diagnostic and Statistical Manual of Mental Disorders, DSM-5, as the'Spectrum of Schizophrenia and Othe...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/jep.12608

    authors: Gonçalves J

    更新日期:2017-10-01 00:00:00

  • Unravelling the polyphony in clinical reasoning research in medical education.

    abstract:RATIONALE:Clinical reasoning lies at the heart of medical practice and has a long research tradition. Nevertheless, research is scattered across diverse academic disciplines with different research traditions in a wide range of scientific journals. This polyphony is a source of conceptual confusion. AIMS AND OBJECTIVE...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/jep.13432

    authors: Koufidis C,Manninen K,Nieminen J,Wohlin M,Silén C

    更新日期:2020-06-22 00:00:00

  • Research results have expiration dates: ensuring timely systematic reviews.

    abstract::Time and timeliness are key issues in appraising and ensuring the clinical relevance of systematic reviews. Time considerations entering the systematic review process include the history of the clinical problem, disease, or treatment that is the target of the review, and the history of the research conducted to addres...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1365-2753.2006.00729.x

    authors: Barroso J,Sandelowski M,Voils CI

    更新日期:2006-08-01 00:00:00

  • Depth of understanding and excellence of practice: the question of wholeness and problem-based learning.

    abstract::The paper evaluates the importance of conceptions underlying practices in medicine and in medical education. It uses a study of anaesthetists' approaches to practice, and of lectures in problem-based learning, to illustrate the influence of a conception of 'applying knowledge in, or to, practice' and of its apparently...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1046/j.1365-2753.2000.00264.x

    authors: Margetson DB

    更新日期:2000-08-01 00:00:00

  • The German version of the Assessment of Chronic Illness Care: instrument translation and cultural adaptation.

    abstract:BACKGROUND:In Switzerland, there is a dearth of information on the extent to which patients with chronic illnesses receive care congruent with the Chronic Care Model (CCM). To drive quality improvement programmes, it is necessary to have practical assessment tools in the country's own language to evaluate the delivery ...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1365-2753.2010.01511.x

    authors: Steurer-Stey C,Frei A,Schmid-Mohler G,Malcolm-Kohler S,Zoller M,Rosemann T

    更新日期:2012-02-01 00:00:00

  • On the causal structure of information bias and confounding bias in randomized trials.

    abstract::Randomized trials are undoubtedly different from observational studies, but authors sometimes propose differences between these designs that do not exist. In this article we examine two claims about randomized trials: first, a recent claim that the causal structure of exposure measurement (information) bias in a rando...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1365-2753.2009.01347.x

    authors: Shahar E,Shahar DJ

    更新日期:2009-12-01 00:00:00

  • A critique of hypertension treatment trials and of their evaluation.

    abstract::Progressive improvements in antihypertensive drug therapy over the past four decades have provided clear benefits in limiting cardiovascular complications. Unfortunately, and largely inexplicably, the inclusion in meta-analyses of defective trials plus the employment of inappropriate diagnostic criteria for adverse co...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2753.2001.00300.x

    authors: Robertson JI

    更新日期:2001-05-01 00:00:00

  • Is "chronic kidney disease" a disease?

    abstract::Several philosophers of medicine have attempted to answer the question "what is disease?" In current clinical practice, an umbrella term "chronic kidney disease" (CKD) encompasses a wide range of kidney health states from commonly prevalent subclinical, asymptomatic disease to rare end-stage renal disease requiring tr...

    journal_title:Journal of evaluation in clinical practice

    pub_type: 杂志文章

    doi:10.1111/jep.13018

    authors: Smart BTH,Stevens RJ,Verbakel JY

    更新日期:2018-10-01 00:00:00