A critique of hypertension treatment trials and of their evaluation.

Abstract:

:Progressive improvements in antihypertensive drug therapy over the past four decades have provided clear benefits in limiting cardiovascular complications. Unfortunately, and largely inexplicably, the inclusion in meta-analyses of defective trials plus the employment of inappropriate diagnostic criteria for adverse coronary events have led to spurious, exaggerated claims for the advantages of such treatment. The consequence has been a devaluation of the very real worth of prophylactic drug therapy for hypertension.

journal_name

J Eval Clin Pract

authors

Robertson JI

doi

10.1046/j.1365-2753.2001.00300.x

subject

Has Abstract

pub_date

2001-05-01 00:00:00

pages

149-64

issue

2

eissn

1356-1294

issn

1365-2753

pii

jep300

journal_volume

7

pub_type

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