Standardized, defined serum-free culture of a human skin equivalent on fibroblast-populated collagen scaffold.

abstract：:Calcium and 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) are promoters of epithelial cell functions; however their effects on sebaceous glands are unknown. In this study, morphology, ultrastructure, cell numbers, lipid synthesis and apoptosis of SZ95 sebocytes were assessed in vitro under different concentrations of extrace...

journal_title：Acta dermato-venereologica

authors： Zouboulis CC,Seltmann H,Abdel-Naser MB,Hossini AM,Menon GK,Kubba R

更新日期：2017-03-10 00:00:00

abstract：:Although palmoplantar psoriasis can be severely disabling, there are very few large clinico-epidemiological studies on this condition. Our purpose was to study the morphology and pattern of lesions in Indian patients with palmoplantar psoriasis and to elucidate the role of occupation in the incidence/localization of t...

journal_title：Acta dermato-venereologica

authors： Kumar B,Saraswat A,Kaur I

更新日期：2002-01-01 00:00:00

abstract：:A 78-year-old man is described, who over 18 years developed three different types of keratoacanthoma: multiple keratoacanthomas, keratoacanthoma centrifugum marginatum and giant keratoacanthoma. Histological examination of the different neoplasms showed similar changes, all typical of a keratoacanthoma. In situ hybrid...

journal_title：Acta dermato-venereologica

authors： Schaller M,Korting HC,Wolff H,Schirren CG,Burgdorf W

更新日期：1996-01-01 00:00:00

abstract：:Experimental infections with Trichophyton mentagrophytes and Trichophyton rubrum were performed on human hair in vitro and studied by conventional light microscopy, scanning (SEM) and transmission (TEM) electron microscopy. The penetrations visible by light microscopy in hair infected with T. mentagrophytes appeared a...

journal_title：Acta dermato-venereologica

authors： Kaaman T,Forslind B

更新日期：1985-01-01 00:00:00

abstract：:Basal cell carcinomas are the most frequent skin cancers in the fair-skinned adult population over 50 years of age. Their incidence is increasing throughout the world. Ultraviolet (UV) exposure is the major carcinogenic factor. Some genodermatosis can predispose to formation of basal cell carcinomas at an earlier age....

journal_title：Acta dermato-venereologica

authors： Basset-Seguin N,Herms F

更新日期：2020-06-03 00:00:00

abstract：:Cutaneous adverse effects of imatinib mesylate (Glivec) are common and various types of skin eruptions have been reported. We report here a 57-year-old man who presented with lichen planus-like lesions on his extremities and palmoplantar hyperkeratosis due to the use of imatinib mesylate for chronic myeloid leukaemia....

journal_title：Acta dermato-venereologica

authors： Kuraishi N,Nagai Y,Hasegawa M,Ishikawa O

更新日期：2010-01-01 00:00:00

abstract：:To elucidate the effect of phototherapy on vitamin D metabolism in psoriatics, the serum concentrations of the major vitamin D metabolites (25-hydroxy-vitamin D (25(OH)D), 1,25-dihydroxy-vitamin D (1,25(OH)2D), and 24,25-dihydroxy-vitamin D (24,25(OH)2D)) were studied in 10 patients with disseminated psoriasis, both b...

journal_title：Acta dermato-venereologica

authors： Staberg B,Oxholm A,Klemp P,Hartwell D

更新日期：1988-01-01 00:00:00

abstract：:Epipodophyllotoxin (VP-16-213) was administered to 9 patients with mycosis fungoides in various stages, most of them in the advanced tumour stage. In 4 of the patients VP-16 was combined with cyclophosphamide. VP-16 alone or in combination with cyclophosphamide was capable of inducing remission initially in all cases,...

journal_title：Acta dermato-venereologica

authors： Molin L,Thomsen K,Volden G,Bergqvist-Karlsson A,Hallberg O,Hellbe L

更新日期：1979-01-01 00:00:00

abstract：:The development of red nail lunulae has been extremely rarely described in alopecia areata. We observed 2 patients, a 30-year-old woman and a 61-year-old man, both suffering from severe alopecia areata, and having red lunulae. The colour changes, which developed a few weeks after the acute onset of hair loss, disappea...

journal_title：Acta dermato-venereologica

authors： Bergner T,Donhauser G,Ruzicka T

更新日期：1992-01-01 00:00:00

abstract：:Two cases of subacute cutaneous lupus erythematosus are described. Features which delayed diagnosis are discussed. The potential clinical and histopathological overlap between this condition and erythema multiforme is emphasized, drawing attention to the histological features which allow distinction. The possibility t...

journal_title：Acta dermato-venereologica

authors： Lyon CC,Blewitt R,Harrison PV

更新日期：1998-01-01 00:00:00

abstract：:Twenty-six patients with chronic dermatophytosis (CD) by Trichophyton rubrum (TR) through one year were included in a double-blind clinical trial with Levamisole/Placebo. All patients were treated with griseofulvin concomitantly. Before, during and after the trial, studies of the cellular and humoral immune response w...

journal_title：Acta dermato-venereologica

authors： Svejgaard E,Christiansen AH,Stahl D,Thomsen K

更新日期：1984-01-01 00:00:00

abstract：:Free fatty acids in sebum arise from lipolytic action of bacterial lipases. We have demonstrated an inhibitory effect of zinc on the lipase of the three Propionibacterium species found in human pilosebaceous follicles. We were also able to show a small corresponding fall in the free fatty acid content of skin surface ...

journal_title：Acta dermato-venereologica

authors： Rebello T,Atherton DJ,Holden C

更新日期：1986-01-01 00:00:00

abstract：:Pruritus is a frequently encountered symptom following burns. Higher intensity of itching has been associated with depth of the wounds and specific body locations but these differences are not well understood. Our aim was to investigate the intensity of post burn pruritus in grafted and non-grafted burns across anatom...

journal_title：Acta dermato-venereologica

authors： Kuipers HC,Bremer M,Braem L,Goemanne AS,Middelkoop E,van Loey NE

更新日期：2015-04-01 00:00:00

abstract：:Etretinate 0.5 mg/kg body weight combined with 0.1% triamcinolone acetonide and 5% salicylic acid in an O/W cream gave more than 70% improvement in 62% of 75 patients. Of this satisfactorily improved group, at least 41% were still in the same condition after 3 years on a maintenance dose of, on average, 0.3 mg/kg body...

journal_title：Acta dermato-venereologica

authors： Polano MK,van der Rhee HJ,van der Schroeff JG

更新日期：1982-01-01 00:00:00

abstract：:A double-blind randomized controlled trial with a paired split-scar design compared verapamil, an L-type Ca2+ channel antagonist, and triamcinolone for prevention of keloid recurrence after excision. Ca2+ channel blocking activity of verapamil in keloid cells was explored. One keloid was excised per subject and each w...

journal_title：Acta dermato-venereologica

authors： Danielsen PL,Rea SM,Wood FM,Fear MW,Viola HM,Hool LC,Gankande TU,Alghamdi M,Stevenson AW,Manzur M,Wallace HJ

更新日期：2016-08-23 00:00:00

abstract：:Papillon-Lefèvre syndrome is an autosomal recessive disorder characterized by palmoplantar hyperkeratosis and aggressive periodontitis. The aim of the study was to identify underlying cathepsin C mutations in 39 subjects with Papillon-Lefèvre syndrome and to explore any phenotypic associations. Genotyping and mutation...

journal_title：Acta dermato-venereologica

authors： Ullbro C,El-Samadi S,Boumah C,Al-Yousef N,Wakil S,Twetman S,Alfadley A,Thestrup-Pedersen K,Meyer B

更新日期：2006-01-01 00:00:00

abstract：:Three-day-old rat skins were treated either by the freezing--thawing method or by the tetraphenylboron technique. After the former procedure, keratohyalin granules were solubilized, leaving empty spaces with an electron-dense or less dense rim. Particles roughly 200 A in diameter, which were either electron-dense or l...

journal_title：Acta dermato-venereologica

authors： Tezuka T,Hirai R

更新日期：1978-01-01 00:00:00

abstract：:Increased expression of cathelicidin antimicrobial peptide (CAMP) is related to the pathogenesis of rosacea. CAMP plays a crucial role in antimicrobial defences, such as the killing of mycobacteria. CAMP gene expression is regulated by vitamin D-dependent (VDR) and vitamin D-independent (C/EBPα) transcription factors....

journal_title：Acta dermato-venereologica

authors： Melnik BC

更新日期：2016-02-01 00:00:00

abstract：:Thirteen patients with port wine stains (PWS) were treated with argon laser therapy. Before and at different points in time following treatment, skin blood perfusion and temperature were mapped with laser Doppler imaging and thermography. In nine patients no elevation in blood perfusion was observed in the PWS in comp...

journal_title：Acta dermato-venereologica

authors： Troilius A,Wårdell K,Bornmyr S,Nilsson GE,Ljunggren B

更新日期：1992-01-01 00:00:00

abstract：:Confounding from comorbidity and socioeconomic status may have biased earlier findings of all-cause mortality among patients with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). We therefore examined all-cause mortality among 72,295 Danish patients with BCC, 11,601 with SCC, and 383,714 age- and gender-m...

journal_title：Acta dermato-venereologica

authors： Jensen AØ,Lamberg AL,Jacobsen JB,Braae Olesen A,Sørensen HT

更新日期：2010-07-01 00:00:00

abstract：:Eosinophilic pustular folliculitis is a rare dermatosis. Recently, in addition to oral indomethacin, other treatments have been applied for eosinophilic pustular folliculitis. The aim of this study was to assess the effectiveness of various therapies encompassing conventional to newly applied drugs for eosinophilic pu...

journal_title：Acta dermato-venereologica

authors： Fukamachi S,Kabashima K,Sugita K,Kobayashi M,Tokura Y

更新日期：2009-01-01 00:00:00

abstract：:A fifty-year-old man with a history of recurrent bronchial and renal infections, and rheumatoid arthritis was admitted with a sunexposure-induced discoid lupus erythematosus. Complement levels and HLA typing of the patient and his family revealed a homozygous C2 deficiency in the patient and his HLA-identical healthy ...

journal_title：Acta dermato-venereologica

authors： Braathen LR,Bratlie A,Teisberg P

更新日期：1986-01-01 00:00:00

abstract：:We describe a case of gingival hyperplasia in a 36-year-old renal transplantation recipient treated with nifedipine for severe arterial hypertension. The appearance of the gingival disorder was probably related to nifedipine intake. Histologically, in addition to the findings of acanthosis, papillomatosis and connecti...

journal_title：Acta dermato-venereologica

authors： Bencini PL,Crosti C,Sala F,Montagnino G,Tarantino A,Menni S,Piccinno R

更新日期：1985-01-01 00:00:00

abstract：:Monocytes form a significant component of the inflammatory reaction taking place in the skin of atopic dermatitis and psoriasis. Chemokines are pivotal in mediating the attraction of leucocytes to sites of inflammation. The CC-chemokine, monocyte chemotactic protein 1 (MCP-1/CCL2), is expressed by keratinocytes in bot...

journal_title：Acta dermato-venereologica

authors： Vestergaard C,Just H,Baumgartner Nielsen J,Thestrup-Pedersen K,Deleuran M

更新日期：2004-01-01 00:00:00

abstract：:Fourteen patients with monosymptomatic delusions of infestation were followed-up 19-48 months after treatment with pimozide was terminated. Seven patients had remained in remission since the treatment. Three had developed relapses, but were without symptoms with intermittent treatment. Four patients responded poorly t...

journal_title：Acta dermato-venereologica

authors： Lindskov R,Baadsgaard O

更新日期：1985-01-01 00:00:00

abstract：:Radiological examination of the hands was performed in 41 patients with systemic sclerosis. Pathological changes were found in 39 patients. Eighteen patients had subcutaneous calcifications and 11 had atrophy of the finger pulps. Bone resorption of ungual tufts was found in 11 patients. Juxta-articular osteoporosis wa...

journal_title：Acta dermato-venereologica

authors： Brun B,Serup J,Hagdrup H

更新日期：1983-01-01 00:00:00

abstract：:Previous studies have shown that magnetic resonance imaging is more sensitive in assessing soft tissue and bone involvement in inflammatory arthritis than conventional radiography. Therefore the main objects of this study were to evaluate the frequency of hand involvement in psoriatic patients free from arthritic symp...

journal_title：Acta dermato-venereologica

authors： Offidani A,Cellini A,Valeri G,Giovagnoni A

更新日期：1998-11-01 00:00:00

abstract：:Although recent therapeutic developments raise hope, melanoma remains a devastating disease with a need for new treatment targets. In other tumours prohormone convertases have been shown to be pro-tumourigenic as they are involved in processing preforms of matrix-metalloproteinases, growth factors and adhesion molecul...

journal_title：Acta dermato-venereologica

authors： Weishaupt C,Mastrofrancesco A,Metze D,Kemper B,Stegemann A,Picardo M,Klein-Szanto AJP,Böhm M

更新日期：2020-05-28 00:00:00

abstract：:Blood levels of serotonin (5-HT) and urinary excretion of 5-hydroxyindole-acetic acid (5-HIAA), tryptamine (T), and indole-acetic acid (IAA) were determined in 39 cases of systemic scleroderma and in 7 cases of very severe cutaneous scleroderma. The T/IAA ratio was normal and serotonin elevated in mild and rather seve...

journal_title：Acta dermato-venereologica

authors： Stachów A,Jabłońska S,Skiendzielewska A

更新日期：1979-01-01 00:00:00

abstract：:Eight out of 30 consecutive patients with AIDS and cryptococcal meningoencephalitis (26,7%) presented cutaneous involvement, in the form of papulo-nodular lesions in 3 patients, molluscum contagiosum-like lesions in 3 patients, and pustular-ulcerative lesions in 2 patients. Skin localization represented an untoward pr...

journal_title：Acta dermato-venereologica

authors： Manfredi R,Mazzoni A,Nanetti A,Mastroianni A,Coronado O,Chiodo F

更新日期：1996-01-01 00:00:00