Abstract:
:Confounding from comorbidity and socioeconomic status may have biased earlier findings of all-cause mortality among patients with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). We therefore examined all-cause mortality among 72,295 Danish patients with BCC, 11,601 with SCC, and 383,714 age- and gender-matched population control cohort subjects with extensive control for comorbidity and socioeconomic status. Data on cancer, death, and socioeconomic status were obtained from medical databases and Statistics Denmark. We analysed data using Cox regression analysis, with estimation of 10-year mortality rate ratios (MRRs) and 95% confidence intervals (CI). Mortality was reduced among patients with BCC (10-year MRR = 0.91 (95% CI: 0.89-0.92) and did not vary by age, comorbidity, or socioeconomic status. Mortality among patients with SCC was increased and varied by age, selected chronic diseases, but not socioeconomic status. The reduced mortality observed among patients with BCC and the increased mortality among patients with SCC persisted even after extensive control for comorbidity and socioeconomic status.
journal_name
Acta Derm Venereoljournal_title
Acta dermato-venereologicaauthors
Jensen AØ,Lamberg AL,Jacobsen JB,Braae Olesen A,Sørensen HTdoi
10.2340/00015555-0899subject
Has Abstractpub_date
2010-07-01 00:00:00pages
362-7issue
4eissn
0001-5555issn
1651-2057journal_volume
90pub_type
杂志文章abstract::The regulation of IgE production in B lymphocytes of patients with atopic dermatitis by interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) was studied. IL-4 stimulated IgE production in vitro in B-cells of healthy donors and of children with atopic dermatitis, but had only a marginal effect on the high basal level ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Radiological examination of the hands was performed in 41 patients with systemic sclerosis. Pathological changes were found in 39 patients. Eighteen patients had subcutaneous calcifications and 11 had atrophy of the finger pulps. Bone resorption of ungual tufts was found in 11 patients. Juxta-articular osteoporosis wa...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::The possible relationship between skin capacitance and the mechanical properties of the skin was studied using non-invasive techniques. Skin hydration was changed by soaking skin with tap water. Hydration of the skin increased the capacitance significantly (p less than 0.01) and hysteresis (creeping phenomenon) (p les...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:102340/0001555570245247
更新日期:1990-01-01 00:00:00
abstract::Dermal cells maintained in cultured human skin explants for up to 10 weeks were studied by electron microscopy. Common findings in the cell organelles were: 1) altered nuclear shapes and numerous nuclear bodies; 2) reduced rough endoplasmic reticulum; 3) a prominent Golgi complex; and 4) an increasing number of free r...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Suction blisters were raised on psoriatic lesions and normal appearing skin. The epidermis was separated at the epidermal-dermal junction. Scanning electronmicroscopy of the dermal side of the blister-roofs from normal looking skin and almost healed psoriatic lesions showed stellate cells probably formed by cytoplasmi...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::An observational, questionnaire-based, cross-sectional study was performed to assess whether differences in coping behaviour (positive and negative strategies) between patients with either a recent diagnosis of malignant melanoma (MM) or with benign dermatological disease, were predictive of the diagnosis. Coping stra...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-1351
更新日期:2012-11-01 00:00:00
abstract::Basement membrane (BM) disruption and dermal changes (elastosis, collagenolysis, vascular ectasia) have been reported in melasma. Although ultraviolet (UV) irradiation can induce these changes, UV is not always necessary for melasma development. Cadherin 11 (CDH11), which is upregulated in some melasma patients, has p...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-2315
更新日期:2016-06-15 00:00:00
abstract::A case of simultaneous occurrence of lichen planus (LP) and hepatitis C in the same patient is presented. The patient had received treatment with interferon alpha for her chronic liver disease, and the association between LP, hepatitis C and interferon alpha treatment is discussed. ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:101080/000155572380
更新日期:1992-09-01 00:00:00
abstract::Dyschromatosis symmetrica hereditaria (OMIM127400) is a rare autosomal dominant pigmentary genodermatosis caused by mutations in the RNA-specific adenosine deaminase (ADAR) gene. This study investigated 5 families and 3 sporadic patients with dyschromatosis symmetrica hereditaria in the Chinese Han population from Anh...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-0168
更新日期:2007-01-01 00:00:00
abstract::This is the first case in the literature describing naevi spili, café-au-lait spots and melanocytic naevi aggregated along-side Blaschko's lines. The pattern of melanocytic lesions in our patient is different from the congenital pigmentary syndromes and the segmental distribution of melanocytic naevi, the quadrant dis...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,评审
doi:10.1080/000155598443114
更新日期:1998-09-01 00:00:00
abstract::Calcium and 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) are promoters of epithelial cell functions; however their effects on sebaceous glands are unknown. In this study, morphology, ultrastructure, cell numbers, lipid synthesis and apoptosis of SZ95 sebocytes were assessed in vitro under different concentrations of extrace...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-2525
更新日期:2017-03-10 00:00:00
abstract::The case is presented of a patient with busulfan (Myleran) treated myeloid leukaemia, who developed bullous pyoderma gangrenosum. Skin symptoms appeared at the time when treatment was discontinued due to signs of bone marrow depression. The pyoderma disappeared following treatment with systemic steroid. ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::The aim of this study, was to observe the effects of KH-1060, a new vitamin D3 analogue, on the dermis of hairless mice by electron microscopy. KH-1060 (0.2 micrograms/ml in isopropanol) or KH-1060 following betamethasone 17-valerate (2 mg/ml in isopropanol) was applied topically to the backs of hairless mice for 4 we...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555577198202
更新日期:1997-05-01 00:00:00
abstract::Indirect immunofluorescence (IF) studies were performed on skin from a variety of vertebrate specimens and IgG fractions from pemphigoid and pemphigus sera. Pemphigoid antigen was present in fish, amphibian, reptilian, avian and mammalian skin, whereas pemphigus antigen was observed in avian and mammalian skin only. ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::In a randomized, controlled parallel group study we have shown that cyclosporine at 3 mg/kg/day is as effective as topical betamethasone-17,21-dipropionate in the treatment of chronic hand eczema. In this study we compared the influence of these therapies on the quality of life. Forty-one patients were treated with ei...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2340/00015555775458
更新日期:1997-01-01 00:00:00
abstract::p38 mitogen-activated protein kinase plays a pivotal role in skin inflammation. The purpose of this study was to investigate the role of the various p38 isoforms. p38β/δ-knockout-C57BL/6 mice were generated, studied in a 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced skin inflammation model and compared with wild-...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-1046
更新日期:2011-05-01 00:00:00
abstract::We present a 32-year-old white patient with congenital reticular ichthyosiform erythroderma, also known as ichthyosis variegata. The patient had typical clinical features with areas of normal appearing skin surrounded by erythematous hyperkeratotic patches. The smaller "confetti-like" patches were mostly present on th...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,评审
doi:10.1080/00015550310002684
更新日期:2003-01-01 00:00:00
abstract::Anorexia nervosa and bulimia nervosa are common yet occult eating disorders which each affect between 1 and 2% of young adult women in the UK (1). Cutaneous signs may provide valuable clues allowing earlier diagnosis. Eating disorders may both imitate (Table I) and complicate other medical illnesses, resulting in unne...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555746869
更新日期:1994-01-01 00:00:00
abstract::A controlled trial of the anti-inflammatory effect of a steroid cream (clobetasol propionate) in 11 patients with moderate acne was assessed over a 3 week period. The placebo cream was the base of the steroid cream. Therapeutic effect was assessed by the number of active and less actively inflamed papules and pustules...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Although desmoplasia has been associated with poor prognoses in cutaneous squamous cell carcinoma, little attention has been paid to the patterns of fibrosis. This study aimed to examine the different stromal fibrotic patterns as markers of metastatic risk. We performed a multicenter retrospective study that included ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,多中心研究
doi:10.2340/00015555-3025
更新日期:2019-01-01 00:00:00
abstract::A case of eosinophilic cellulitis (Wells' syndrome) in association with ascariasis is described. The clinical and histopathologic features of the patient responded well to an oral anthelminthic drug. According to our search, this association has not previously been reported. ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555574292294
更新日期:1994-07-01 00:00:00
abstract::A review of a variety of cutaneous paraneoplastic conditions is presented. Although the conditions discussed appear in only 7-15% of cancer patients, they are considered indicators of possible underlying malignancy. ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,评审
doi:10.2340/0001555573161170
更新日期:1993-06-01 00:00:00
abstract::Psoriasis is a chronic inflammatory dermatosis, frequently presenting with chronic itch. This study investigated the prevalence and detailed clinical characteristics of chronic itch in 143 psoriatic patients, with regard to different age groups, comorbidities and pharmacotherapy. Chronic itch was reported by 72% of su...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-3147
更新日期:2019-04-01 00:00:00
abstract::Patients with atopic dermatitis were found to have an about 7-fold increased spontaneous proliferative response of peripheral blood lymphocytes and an about 4-fold elevation of CD3-dependent lymphocyte transformation as compared to normal controls. The CD3-dependent lymphocyte response in patients with severe atopic d...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555575353356
更新日期:1995-09-01 00:00:00
abstract::Eye colour, hair colour and skin colour are important risk factors for malignant melanoma and non-melanoma skin cancers. There are few studies in which the distribution of these pigmentary factors in risk populations has been assessed. The purpose of this study was to investigate the prevalence of the major eye and ha...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.1080/000155598441567
更新日期:1998-05-01 00:00:00
abstract::The Scandinavian Mycosis Fungoides Study Group has treated 21 patients with mycosis fungoides in plaque stages with topical, whole-body application of nitrogen mustard, 20 mg in 40 ml water per square metre. Ten patients were treated after previous attempts at intravenous tolerance induction ad modum van Scott & Kalma...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::In order to find image descriptors enabling the characterization of sclerotic skin of morphea plaques and their objective differentiation from normal skin, we studied 52 lesions in 35 patients affected by plaque type morphea. Echographic evaluations were carried out using a 20 MHz B-scanner, providing cross-sectional ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555575442445
更新日期:1995-11-01 00:00:00
abstract::Ciprofloxacin (CPFX) is a widely used fluoroquinolone antibiotic, inducing cutaneous adverse drug reactions in about 1 to 2% of the treated patients. Conclusive diagnosis of drug allergy, however, still remains a major problem in daily clinical practice. Here, we present 2 patients with drug allergy to CPFX. In both c...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555577285288
更新日期:1997-07-01 00:00:00
abstract::Psoriasin, which is highly expressed in psoriasis, is encoded by a gene located within the epidermal differentiation complex. The aim of this study was to investigate the effect of endogenous psoriasin on disturbed keratinocyte differentiation in psoriasis. Immunohistochemical staining revealed a gradient of psoriasin...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-2596
更新日期:2017-04-06 00:00:00
abstract::The anti-inflammatory mechanisms of minocycline, an antibiotic used in the treatment of the inflammatory component of acne, are only partially understood. In addition to inflammation due to cytokines (IL-1, IL-6, TNF-alpha, etc.), recent studies have shown that neuropeptide-mediated neurogenic inflammation may play an...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.1080/000155599750010625
更新日期:1999-07-01 00:00:00