Abstract：
INTRODUCTION:Patients with septic shock often receive intravenous vasopressor infusions, with little evidence available to guide their titration. We surveyed Canadian intensivists to document self-reported vasopressor titration strategies for patients with septic shock. METHODS:We identified Canadian intensivists caring for adult patients by merging membership lists of 3 Canadian critical care associations. We invited respondents to complete a scenario-based questionnaire to understand triggers for vasopressor use, target blood pressure values, and the influence of chronic comorbidities and acute illnesses on vasopressor prescription. RESULTS:Sixty-three percent of eligible intensivists completed our survey. Most respondents (82.6%) would frequently or always administer vasopressor therapy for isolated hypotension but not for other isolated signs of organ failure (such as elevated serum lactate or low urine output). Respondents defined low blood pressure using mean arterial pressure (83.7%) and aimed for higher values when resuscitating a patient with multiple organ failure. Chronic comorbidities and acute concurrent illnesses had variable effects on stated vasopressor prescription. Norepinephrine (94.8%) was the preferred first-line vasopressor. CONCLUSIONS:Self-reported vasopressor use for the treatment of septic shock is relatively uniform among Canadian intensivists; however, practice is variable in patients with chronic comorbidities or acute concurrent illnesses.
journal_name
J Crit Carejournal_title
Journal of critical careauthors
Lamontagne F,Cook DJ,Adhikari NKJ,Briel M,Duffett M,Kho ME,Burns KEA,Guyatt G,Turgeon AF,Zhou Q,Meade MOdoi
10.1016/j.jcrc.2011.01.005subject
Has Abstractpub_date
2011-10-01 00:00:00pages
532.e1-532.e7issue
5eissn
0883-9441issn
1557-8615pii
S0883-9441(11)00037-2journal_volume
26pub_type
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