Abstract:
:In this study, the feasibility of Integra acellular collagen used as a vascular carrier in skin flap prefabrication was examined. In all, 20 Sprague--Dawley rats were randomly divided into 3 groups. The saphenous vascular bundle was used as the vascular carrier. In group 1 (n = 8), an arteriovenous fistula was made by anastomosis of distal saphenous artery and vein. An Integra patch (2 × 3 cm²) was placed underneath the vascular bundle. In group 2 (n = 6), an Integra patch was placed on the top of the saphenous vessels, which remained intact. In group 3 (n = 6), an arteriovenous fistula was made without Integra implant. Two weeks after the initial management, a skin flap (2 × 3 cm² in size) was raised and replaced in each group. The survival of the flaps and histology were evaluated at 7 days after flap replacement. The results showed that the average survival area in group 1 was 98% ± 2%. No flap survival was observed in group 2. The mean survival area in group 3 was 29% ± 6%. The differences among all 3 groups were significant (P < 0.05). Although the mean survival area in group 3 was significantly lower than that in group 1 (P < 0.001), it was significantly higher than that in group 2. Histology showed that the Integra patch was incorporated into the adjacent connective tissue, and increased amounts of neovascularization were seen between the collagenous sheets and dermis in group 1. In conclusion, this study demonstrated that Integra acellular collagen can incorporate into the adjacent tissue as a vascular carrier and induce angiogenesis in flap prefabrication. This biomaterial can provide a scaffold for supporting and enhancing the survival of a vascular prefabricated skin flap. The results indicate that this material is an ideal biomaterial for flap prefabrication and may be used for this clinical purpose in the future.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Yan H,Black D,Jones NI,McCraw J,Chen H,Arnold P,Zhang Fdoi
10.1097/SAP.0b013e3181fabc32subject
Has Abstractpub_date
2011-09-01 00:00:00pages
299-302issue
3eissn
0148-7043issn
1536-3708journal_volume
67pub_type
杂志文章abstract::Textured silicone expanders are alleged to be less painful in the filling process, to have less capsular contracture, and to stay in position better than smooth silicone expanders. To test these three hypotheses, 6 patients undergoing bilateral simultaneous expander implant placement for breast reconstruction after ma...
journal_title:Annals of plastic surgery
pub_type: 临床试验,杂志文章
doi:10.1097/00000637-199403000-00001
更新日期:1994-03-01 00:00:00
abstract::Soft tissue defects in the periolecranon region are difficult to manage by standard techniques such as closure by approximation, split-thickness skin grafting, or healing by secondary intention. We employed cadaver injections and dissections to study the vascular anatomy of the periolecranon region in search of a suit...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198504000-00010
更新日期:1985-04-01 00:00:00
abstract:BACKGROUND:National plastic surgery society web sites are an important source of information for patients, family members, and healthcare professionals. There are currently no standardized recommendations for the information provided on web sites. The aim of this study was to assess the information available on each na...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002447
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to systematically review and analyze the available evidence on the role of surgery in improving outcomes in patients with migraine headaches. METHODS:An electronic search of PubMed, Scopus, CENTRAL (Cochrane Central Register of Controlled Trials), and Google Scholar database...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,meta分析
doi:10.1097/SAP.0000000000001743
更新日期:2019-08-01 00:00:00
abstract::Using an enzyme-linked immunosorbent assay, we investigated the amount of cell surface fibronectin and the amount released to the culture medium in human skin fibroblasts during successive cultivation. Cell surface fibronectin did not show a remarkable change in quantity through early and midpassage, but it decreased ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198503000-00010
更新日期:1985-03-01 00:00:00
abstract::Coronoid process hyperplasia (CPH) is an uncommon disorder characterized by an enlarged coronoid process impinging against the posterior aspect of the zygomatic arch. Young male adults are usually affected, presenting with limited mouth opening, which is typically painless and progressive in nature. The diagnosis of t...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:Ketorolac tromethamine (Toradol) is an effective a nonsteroidal anti-inflammatory drug and a powerful analgesic for patients undergoing breast surgery. However, the potential for postoperative bleeding has not yet been explored specifically in women undergoing implant-based breast reconstruction. There is co...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001409
更新日期:2018-05-01 00:00:00
abstract::The medial sural(MEDIAL GASTROCNEMIUS) perforator flap has previously been described as a free flap distinguished by the potential for a large yet thin cutaneous flap that incorporates the calf skin territory. Its medial sural vascular pedicle can be tailored to allow reach extending from the popliteal fossa to the su...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000116338.59679.12
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:The prepuce is an excellent donor site for skin grafts with minimal donor site morbidity. Full-thickness grafts are often required for correction of congenital syndactyly and in burn contractures. METHODS:Preputial skin was used for grafting in 18 children: 5 with burn contractures and 13 with congenital sy...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001644
更新日期:2018-12-01 00:00:00
abstract::We analyzed the complications in a series of 126 fasciocutaneous flaps. The overall complication rate was 40%, which included both early and late complications. The early complications were divided into major and minor groups. The main avoidable causes of major complications were poor design; the presence of orthopedi...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198709000-00009
更新日期:1987-09-01 00:00:00
abstract::Giant omphalocele is a rare, large abdominal wall defect in which the intra-abdominal organs herniate through the umbilical cord and are covered by a sac. Surgical management of giant omphalocele is challenging, and optimal treatment remains controversial. Two generally accepted treatment options are staged closure an...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000589
更新日期:2016-06-01 00:00:00
abstract::Although various techniques have been reported to correct blepharoptosis, undercorrection is still a commonly occurring complication and needs further revision procedure. Scar formation and distorted anatomy make reoperation more difficult than the primary surgery. However, tarsus is usually fully maintained in the fi...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000223
更新日期:2015-12-01 00:00:00
abstract::Avulsion fractures can pose technical difficulties for surgical fixation. The fragments are often small and around finger joints with access being difficult due to attachment of ligaments or tendons. Traditionally, these have been treated using K wires, lag screws, or pullout sutures.Hook plates were originally descri...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001119
更新日期:2017-09-01 00:00:00
abstract:INTRODUCTION:The modified Meek micrografting technique has been used in the treatment of severely burned patients and a number of articles have examined the use of the modified Meek technique in adults and in mixed-age groups. However, there is a paucity of research pertaining to the outcome in the pediatric age group....
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001565
更新日期:2018-09-01 00:00:00
abstract::Although the etiology of nonsyndromic forms of craniosynostosis remains uncertain, recent experiments from our laboratory have demonstrated that fetal head constraint induces cranial suture fusion in mice through a process associated with altered patterns of transforming growth factor beta (TGF-beta) isoform expressio...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200105000-00015
更新日期:2001-05-01 00:00:00
abstract::Despite the recent overall increase in cases of tuberculosis and other types of mycobacterial infection, the incidence of tuberculous hand infections remains extremely low in the United States. The rarity of this infection often results in delay in diagnosis and treatment. A case of Mycobacterium tuberculosis infectio...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-199801000-00014
更新日期:1998-01-01 00:00:00
abstract::Piezoelectric sensors have been shown to respond reproducibly to changes in tissue mechanical properties surrounding an implant over a 4-month period. The vibrational amplitude at a frequency corresponding to the radial resonance shows a statistically significant change over time. The initial period of inflammation is...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000189620.45708.5f
更新日期:2006-01-01 00:00:00
abstract::A superior advantage of the superficial circumflex iliac artery perforator flap is that any donor site residue can easily be hidden by clothing. Usually designed as narrow or moderate-sized flaps based on medial perforators of the superficial branch, this readily allows primary donor site closure. However, for larger ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002159
更新日期:2020-08-01 00:00:00
abstract::Extra-articular crystalline deposition secondary to gout, and less commonly, pseudogout is a well known phenomenon. Despite this well-documented entity of extra-articular deposition, there have been few reports of infiltration of the flexor tendon sheath of the hand. Here, we present a case series of this unique occur...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181788e98
更新日期:2009-02-01 00:00:00
abstract::There is general agreement that Dupuytren's contracture is a genetic disorder that occurs predominantly in white men of Northern European ancestry. It appears rarely in the purely black population. We present our experience from Temple University of 8 black patients with Dupuytren's contracture. We also present a revi...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-199406000-00010
更新日期:1994-06-01 00:00:00
abstract::Circumcision is a commonly performed minor surgical procedure; however, it may lead to serious complications if performed by poorly trained health care providers. In this case report, a subglanular stricture causing a mushroom-like deformity resulting from circumcision is presented. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.SAP.0000024754.83430.05
更新日期:2003-02-01 00:00:00
abstract::Lymphedema is a condition characterized by progressive swelling and adipose deposition that occurs commonly after lymphadenectomy. Recent clinical studies have suggested that the transfer of lymph nodes to the lymphedematous limb can improve lymphatic function. In this report, we investigate dynamic modulation of lymp...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000428
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Complications after immediate breast reconstruction pose a significant challenge to the reconstructive surgeon. Known risk factors include smoking, obesity, age, and adjuvant oncologic therapies. Less is known about the association between axillary lymph node dissection (ALND) and the development of postoper...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000653
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Obstetric brachial plexus palsy is caused by traction during birth. Most patients regain useful function with spontaneous recovery. In some cases, cross reinnervation occurs between the biceps and triceps muscles. In these cases, smooth active motion of the elbow joint is impaired by simultaneous biceps and ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002075
更新日期:2019-10-01 00:00:00
abstract::The origins of electrosurgery are presented and recognition given to one of its forgotten pioneers, William T. Bovie. Though not a physician, Bovie contributed greatly to patient care. ...
journal_title:Annals of plastic surgery
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1979-02-01 00:00:00
abstract::Nitric oxide (NO), identified as the mediator of endothelium-dependent relaxation of vascular smooth muscle, is known to cause a number of inflammatory conditions, especially in ischemia/reperfusion injury. This experimental study, using a rabbit epigastric island flap, was designed to investigate whether skin flap is...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199712000-00009
更新日期:1997-12-01 00:00:00
abstract::Fourteen patients with erythematous and/or hypertrophic scars resulting from remote surgical excision or trauma were evaluated and subsequently treated with one to two flashlamp-pumped pulsed dye (585 nm) laser treatments over a 2-month period. Clinical assessments were performed before commencement and at the end of ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199402000-00015
更新日期:1994-02-01 00:00:00
abstract::Noma is primarily affecting children in underprivileged countries and results in disfiguring facial defects, loss of mandibular movement, and subsequent social disintegration. Plastic surgery in West Africa traditionally uses pedicled flaps. In large, complex, or central facial defects, though, pedicled flaps are apt ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000165688.50780.e9
更新日期:2005-08-01 00:00:00
abstract::Forearm and wrist injuries can result in a nonfunctional hand caused by loss of motor and sensory functions. Psychological stress is known to accompany traumatic hand injuries and may therefore affect functional outcome. The authors conducted a retrospective study of 107 patients diagnosed with a median, ulnar, or com...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200207000-00013
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:Traumatic and nontraumatic defects of the distal third of the tibia are challenging in regard to soft tissue coverage. While local, pedicled fasciocutaneous perforator flaps allow adequate coverage, the donor site often requires skin grafting. When a local perforator flap is designed as a 180-degree propelle...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31803c9b66
更新日期:2007-12-01 00:00:00