Abstract:
:Nitric oxide (NO), identified as the mediator of endothelium-dependent relaxation of vascular smooth muscle, is known to cause a number of inflammatory conditions, especially in ischemia/reperfusion injury. This experimental study, using a rabbit epigastric island flap, was designed to investigate whether skin flap ischemia followed by reperfusion-influenced serum NO and c-GMP concentrations in the flap. In addition, we also investigated the premedicated effects of the NO synthase inhibitor and heparin on serum NO and c-GMP concentrations in skin flap ischemia/reperfusion. Serum NO concentration after 15, 30, 45, and 60 minutes of ischemia followed by reperfusion significantly increased compared with that in nonischemic control and elevated flaps. On the contrary, serum NO concentration was suppressed in L-NAME or aminoguanidine pretreated animals with ischemic group. Administration of heparin increased the serum NO concentration in elevated flaps, but suppressed it in ischemic flaps followed by reperfusion. The changes in serum c-GMP and NO concentrations were related in all of the experimental groups. These results suggest that NO may be derived from vascular endothelial cells and dilate peripheral vessels in compensation for ischemia.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Oshima H,Inoue H,Aihara M,Tomioka M,Ishida Hdoi
10.1097/00000637-199712000-00009subject
Has Abstractpub_date
1997-12-01 00:00:00pages
608-14issue
6eissn
0148-7043issn
1536-3708journal_volume
39pub_type
杂志文章abstract::Reconstruction of intraoral defects is one of the main aspects of head and neck cancer treatment. Since the advent of microvascular surgery in this field, free flap tissue transfer has become a common procedure, and various flaps have been described for soft tissue reconstruction. The lateral upper arm free flap is on...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001876
更新日期:2019-12-01 00:00:00
abstract::In previous studies, we were able to demonstrate baseline non-augmented cadaveric silicon tissue values as well as silicone-augmented breast capsular tissue silicon levels from various geographic locations in the United States. One of the limitations of these previous studies was the potential for intracapsular variat...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199612000-00004
更新日期:1996-12-01 00:00:00
abstract::Incisional hernias develop in 2% to 11% of patients who undergo laparotomy. Prosthetic mesh repair provides more strength, tension-free closure, and decreased recurrence rates as compared to primary tissue repairs. Complications-fistula formation, adhesions, skin erosion, and seroma/abscess formation-however, include ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318212f380
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:The aim of this study was to demonstrate the viability of the transverse circumflex scapular artery perforator flap (TCSAPF) in children with soft tissue defects of the lower limb. METHODS:In an anatomic study, 25 fresh cadavers were injected with lead oxide-gelatin for spiral computed tomography and 3-dimensi...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002365
更新日期:2020-05-01 00:00:00
abstract::Severe, work-related hand injuries are often accompanied by a significant number of psychological symptoms that are frequently associated with posttraumatic stress disorders. These symptoms occur in the following four domains of psychological functioning: cognitive, affective, physiological, and behavioral. This study...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199212000-00010
更新日期:1992-12-01 00:00:00
abstract::With a rise in tissue expander-based breast reconstructions (TEBRs) using acellular dermal matrix (ADM), we have seen an increase in ADM-specific complications. In this study, we aimed to evaluate clinically significant seroma (CSS) formation-defined by the need for a drainage procedure-to determine if there was a dif...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3182923dc9
更新日期:2013-09-01 00:00:00
abstract::Limited access to hand surgical care in the emergency room appears to be a problem in north Florida and probably other parts of the country, as well. In this study, hand surgeons in 3 major cities were contacted to determine what on-call services they provide for hospital emergency departments in their areas. Addition...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000237636.37714.bb
更新日期:2007-02-01 00:00:00
abstract::Idiopathic avascular necrosis of the scaphoid, or Preiser disease, is a rare condition. Both the etiology and the pathology are still not well understood. We here present 2 cases with this disease and discuss the recommended treatment according to the stage of disease progression and by reference to previous studies i...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0b013e31827fafa1
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Application of collagen products to wounds has been shown to improve wound healing. Using a collagen-based hydrogel (cHG) capable of cellular support previously developed by our laboratory, we hypothesize that our hydrogel will increase the speed of wound healing by providing a 3-dimensional framework for ce...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002380
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Children with giant congenital nevomelanocytic nevi (CNN) are referred to our pediatric burn center for the surgical management of this disfiguring and potentially malignant skin disorder. Use of tissue expanders has contributed significantly in limiting donor site morbidity associated with treatment of gian...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318095a784
更新日期:2008-03-01 00:00:00
abstract::Fibromuscular dysplasia is an uncommon angiopathy that is principally observed in the renal and carotid arteries. Digital ischemia resulting from fibromuscular dysplasia of the forearm arteries is a rare occurrence. This article describes a case of distal radial and ulnar artery fibromuscular dysplasia presenting as p...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199412000-00017
更新日期:1994-12-01 00:00:00
abstract::A 66-year-old woman with an abdominal wound caused by infected synthetic mesh had failed to heal in spite of many surgical attempts to close the wound. A sealed transparent vinyl chamber was glued to the periphery of the wound and antibiotics in high concentrations (up to 2,500 times the minimum inhibitory concentrati...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199601000-00016
更新日期:1996-01-01 00:00:00
abstract::Many techniques have been developed for the correction of eyelid ptosis. A new tarsal plate resection technique is described for use in cases of minimal ptosis with fair to good levator function. The procedure involves a horizontal lenticular excision of the tarsal plate, placed so that equal amounts of tarsus remain ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199007000-00002
更新日期:1990-07-01 00:00:00
abstract::Cryopreservation has the potential to improve availability of donor parts for composite tissue allotransplantation and may reduce their antigenicity. This study investigates whether the component tissues of composite flaps remain viable after cryopreservation. Forty-one epigastric flaps were harvested from Lewis rats....
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000245114.96202.62
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:The use of human acellular dermal matrices (ADM) has become routinely used in implant-based breast surgery. Notwithstanding the many benefits for tissue support, the morbidity associated with its use includes seroma and infection, among other potential complications. Some patients experience a specific complica...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000475
更新日期:2015-05-01 00:00:00
abstract::Oncologic resection of musculoskeletal sarcoma sometimes requires reconstruction with vascularized soft tissue transplantation. To date, few reports have described treatment outcomes of such cases. In the present study, 55 cases were enrolled to examine oncologic/functional outcomes, complications, and the risks for p...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31817fe4b3
更新日期:2009-03-01 00:00:00
abstract::Local infection is a rare complication after aesthetic rhinoplasty. In the past serious complications and 1 death have been reported. We present 5 cases of local infection after primary and secondary procedures. Infection seems to have more to do with technical details during an operation, such as the external lateral...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198610000-00007
更新日期:1986-10-01 00:00:00
abstract:INTRODUCTION:Sacropelvic resection is the treatment of choice for pelvic bone tumors and can be associated with intraoperative electron radiotherapy (IOERT) to optimize local control of the disease. Reconstruction with flaps also is essential to avoid pelvic complications. There is scarcity of publications evaluating o...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002571
更新日期:2020-12-15 00:00:00
abstract:INTRODUCTION:The combined approach using both an implant and autologous tissue for breast reconstruction has become more common over the last 10 years. We sought to provide a systematic review and outcomes analysis of this technique. METHODS:We searched PubMed and the Cochrane Library database to identify studies that...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002085
更新日期:2020-06-01 00:00:00
abstract::Skin grafting is a modern addition to surgery but with ancient roots. Its biology has come to light only within the last 50 years, and research continues into its basic mechanisms. A brief history of skin grafting from Susruta to Reverdin and Ollier and the mechanisms of skin grafting featuring recent research effects...
journal_title:Annals of plastic surgery
pub_type: 历史文章,杂志文章,评审
doi:10.1097/00000637-198810000-00011
更新日期:1988-10-01 00:00:00
abstract:BACKGROUND:Head and neck arteriovenous malformations (AVMs) involving branches of the facial nerve often cause tremendous cosmetic, functional, and psychological problems that are challenging to treat. We proposed an algorithm to obtain the optimal treatment and esthetic outcome. METHODS:Medical records of 24 patients...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001494
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Suboptimal pain management is a common, yet largely unrecognized, problem in the postsurgical patient population. Current treatment protocols heavily rely on opioid use and, though generally effective in providing pain relief, are associated with multiple side effects. The present systematic review aims to o...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001916
更新日期:2019-12-01 00:00:00
abstract:INTRODUCTION:The most effective management of a patient with sarcoma is surgical resection. Often the resection is performed, the wound is irradiated, adjuvant chemotherapy is administered, and the wound is closed without plastic surgery consultation. Wound complications, after these treatment protocols, often require ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31827c7973
更新日期:2013-09-01 00:00:00
abstract::Axillary hyperhidrosis, although not life-threatening, is a troublesome condition which produces a personal and social handicap of great significance to patients for many years before they seek a cure. Treatment has consisted of application of topical antiperspirants, systemic anticholinergic medications, excision and...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198712000-00013
更新日期:1987-12-01 00:00:00
abstract::Pigmented lesions of the nail bed, especially without a history of trauma, represent a diagnostic challenge to the clinician. These lesions are often categorized as melanonychia striata (MS), which refers to any linear tan-brown-black pigmentation of the nail bed. The differential diagnosis of MS includes subungual he...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199608000-00002
更新日期:1996-08-01 00:00:00
abstract::A bayonet-shaped airway allowing free respiration and undisturbed deglutition was reconstructed in 2 young women who had undergone tracheotomy and radiotherapy for thyroid carcinoma. The laryngeal vestibule, glottis, and subglottis had been destroyed, and the air passages were closed. An external gutter and an anterio...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198605000-00010
更新日期:1986-05-01 00:00:00
abstract:INTRODUCTION:The peripheral adipose tissue is a vital component of many procedures in reconstructive and esthetic surgery. There is a limited knowledge on hemodynamic changes of adipose tissue. A direct intravital microscopic observation method is needed for the measurement of microcirculatory changes occurring in peri...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31814da751
更新日期:2008-06-01 00:00:00
abstract::A Silastic tissue expander inserted subpectorally at the time of modified radical mastectomy has provided early development of the reconstructive envelope, thereby simplifying matching of the contralateral breast. Significant emotional support for the woman faced with imminent loss of her breast has been repeatedly ob...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198511000-00007
更新日期:1985-11-01 00:00:00
abstract::The authors report a method of reconstruction of a full-thickness lower eyelid defect using a blepharoplasty technique utilizing excess skin of the lower eyelid with a hard palate mucosal graft. In all patients the hard palate mucosa took well, and good functional and aesthetic results were obtained. The most suitable...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199906000-00019
更新日期:1999-06-01 00:00:00
abstract::Five patients each with grade IIIB or IIIC distal tibial injuries are presented. All patients were treated initially by multiple debridements and external fixation of the tibial fracture. After failure of the primary treatment, each patient underwent microsurgical free muscle transfer and bone transport of the proxima...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199302000-00001
更新日期:1993-02-01 00:00:00