Abstract:
OBJECTIVE:Studies have shown that platelets play an important role in the pathophysiology of vaso-occlusive crises (VOC) in sickle cell disease. This study investigates whether changes in platelet indices from baseline can be predictive of complications during acute pain crisis. METHODS:Data were obtained from pediatric sickle cell patients in the well-clinic setting and compared with data gathered during VOC (n = 67). Primary outcome was complicated (admission, acute chest syndrome, transfusion, etc) versus uncomplicated (discharge from emergency department without subsequent return) course. RESULTS:Patients with uncomplicated courses had larger platelet declines (53.7) than those with complicated courses (14.8, P = .005). CONCLUSIONS:The study suggests that patients with uncomplicated VOC are more likely to experience a larger decline in platelets. The predictive value is limited by the need to have preexisting steady-state data and relatively small decline. Ongoing studies are needed to identify useful laboratory data to help predict severity of VOC.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Shanley LA,Ebeling M,Titus MOdoi
10.1177/0009922811399347subject
Has Abstractpub_date
2011-07-01 00:00:00pages
657-61issue
7eissn
0009-9228issn
1938-2707pii
0009922811399347journal_volume
50pub_type
杂志文章abstract::Two hundred and seventy one infants were enrolled in a study to compare six different methods of treating the umbilical cord. Antimicrobial control was equal for all methods. Repeated triple dye application was considered least acceptable by staff and parents and had the longest attachment time. Povidone-iodine was as...
journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000992288802700302
更新日期:1988-03-01 00:00:00
abstract::Ninety low socioeconomic adolescent females (aged 16-22 years, means 18.6 years) were screened for rubella immunity using a rubella IgG enzyme immunoassay. Data concerning past immunizations (with documentation, if possible), prior rubella disease, and previous pregnancies were gathered through direct interviews. Resu...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502400705
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abstract::Personal health records (PHRs) have the potential to improve incomplete health records. However, internet access through traditional methods may be limited for populations most at risk for fragmented care. A convenience sample of postpartum women at a community hospital and tertiary-care academic center in New York Ci...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922816673438
更新日期:2017-04-01 00:00:00
abstract::During 1981, we treated 20 infants, less than 24 months old, for nontyphoid Salmonella (NTSal) gastroenteritis (GE). Blood cultures were obtained in 17 cases, and Salmonella bacteremia was demonstrated in 8 (47%). Of the 13 children 3 to 24 months of age, 7 (54%) had positive blood cultures. One child (8 months old) a...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288302200901
更新日期:1983-09-01 00:00:00
abstract::This article, Part 2 of a five-part series on The Web, Communications Trends, and Children's Health, describes how the Web's "virtual library" lets pediatricians tap into an evergrowing body of resources, including the latest medical information and online Continuing Medical Education. In addition, the Web creates new...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289803700401
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abstract::Anemia is defined as a reduction in red blood cell mass or hemoglobin concentration in blood. It is statistically differentiated from normal states as a hemoglobin concentration or hematocrit 2 SD below the mean for the healthy population adjusted for age and sex. Anemias may be classified based on the morphologic fun...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922808323115
更新日期:2009-01-01 00:00:00
abstract::The American Academy of Pediatrics California Chapter 3 created a 20-minute training video targeting barriers to strong provider recommendation of the human papillomavirus (HPV) vaccine. The video included clinical vignettes featuring pediatricians modeling counseling techniques with vaccine-hesitant families. Ninety-...
journal_title:Clinical pediatrics
pub_type: 杂志文章
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abstract:BACKGROUND AND OBJECTIVES:Little is known about the magnitude of multiple chronic conditions (MCC) in children. This study describes the prevalence of and patterns of comorbidities in children receiving Medicaid assistance. METHODS:Diagnoses from 5 years of Medicaid claims data were reviewed and identified 128,044 chi...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922815574073
更新日期:2015-04-01 00:00:00
abstract::Childhood celiac disease (CD) is considered rare in the United States. Consequently there are few data concerning its clinical presentation. A validated questionnaire was distributed to families of children with CD. One hundred forty-one children with biopsy-proven CD were included in the study. We found significant d...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280504400309
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abstract::The purpose of this study was to determine the efficacy and safety of propofol sedation for pediatric procedures in the emergency department. For patients needing painful procedures, propofol was administered intravenously. Vital signs, complications, and time to recovery were recorded. Patient amnesia and parent, pat...
journal_title:Clinical pediatrics
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doi:10.1177/000992280104001204
更新日期:2001-12-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922812467531
更新日期:2013-01-01 00:00:00
abstract::English- and Spanish-speaking parents of 1- to 5-year-old children were invited to view 5-10 minutes of parent training program, "Play Nicely," as part of the well-child checkup. Key measures were parents' plans to change how they discipline and, if they planned to use less spanking, how the program worked in their si...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922817693298
更新日期:2018-02-01 00:00:00
abstract::This study investigates relations between language and cognitive scores in children with receptive language (RL) delay and suggests guidelines for referral for cognitive testing. This retrospective review of the test scores of 41 children, ages 17 to 76 months (mean = 37.7 months), focuses on examining associations be...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922808323108
更新日期:2009-01-01 00:00:00
abstract::A study of 64 infants from one to six months of age was made using the 32-hour parenteral magnesium load test. Most of the infants were studied for neuromuscular hyperirritability or other signs compatible with magnesium deficiency; some with unrelated problems served as controls. Magnesium retention below 40 per cent...
journal_title:Clinical pediatrics
pub_type: 杂志文章
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更新日期:1975-05-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922815608278
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journal_title:Clinical pediatrics
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更新日期:2018-11-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992287701600310
更新日期:1977-03-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 信件
doi:10.1177/000992289303200515
更新日期:1993-05-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500913
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280604500211
更新日期:2006-03-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
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更新日期:2012-08-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289002900309
更新日期:1990-03-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992280003900401
更新日期:2000-04-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992287901801103
更新日期:1979-11-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922818822975
更新日期:2019-01-07 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288402300709
更新日期:1984-07-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280504400804
更新日期:2005-10-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
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更新日期:1993-03-01 00:00:00
abstract::The present report is a review of all 554 papers published on Medline on pedophilia. The first discussion is the history of the disorder from ancient Greece to the present time, especially the influence of the liberal country of the Netherlands, the North American Man-Boy Love Association, and the sexual crisis in the...
journal_title:Clinical pediatrics
pub_type: 历史文章,杂志文章,评审
doi:10.1177/0009922807301483
更新日期:2007-10-01 00:00:00