Feulgen staining remains the gold standard for precise DNA image cytometry.

abstract：AIM:To report the outcome of radiation therapy (RT) +/- chemotherapy in HIV-seropositive patients with Head and Neck Squamous Cell Carcinoma (HNSCC). PATIENTS AND METHODS:This is the largest single-Institution retrospective study to date, consisting of 73 HIV patients with HNSCC treated from January 1997-2010. The med...

journal_title：Anticancer research

authors： Mourad WF,Hu KS,Shasha D,Concert C,Ishihara D,Lin W,Gamez ME,Lukens JN,Shourbaji RA,Ryniak M,Li Z,Culliney BE,Khorsandi AS,Tran T,Jacobson A,Manolidis S,Schantz S,Urken M,Persky MS,Harrison LB

更新日期：2013-12-01 00:00:00

abstract：:The cyclin-dependent kinase inhibitor (CDK1) p27(kip1) is a negative regulator of cell cycling and has antitumor effects. In our previous study, the recombinant adenovirus expressing wild-type p27(kip1) (Adp27-wt) induced cell cycle arrest and apoptosis, and proved that p27 is a tumor suppressor gene like p53. Another...

journal_title：Anticancer research

authors： Shiraso S,Katayose Y,Yamamoto K,Mizuma M,Yabuuchi S,Oda A,Rikiyama T,Onogawa T,Yoshida H,Hayashi H,Ohtsuka H,Motoi F,Egawa S,Kato J,Unno M

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:One of the challenges to improving access to care is identifying disparities in health care. To determine the influence of insurance status on outcome for patients with non-small cell lung cancer (NSCLC), we analyzed data from the National Cancer Data Base (NCDB) from 1998-2011. MATERIALS AND METHODS:Data f...

journal_title：Anticancer research

authors： Shi R,Diaz R,Shi Z,Duvall E,Mills G

更新日期：2016-01-01 00:00:00

abstract：AIM:Hepatic resection has become the standard treatment for patients with primary or metastatic liver malignancies. The aim of our study was to evaluate the clinical outcome of hepatic resection in patients with advanced ovarian cancer (AOC). PATIENTS AND METHODS:All patients undergoing hepatic resection for AOC in ou...

journal_title：Anticancer research

authors： Neumann UP,Fotopoulou C,Schmeding M,Thelen A,Papanikolaou G,Braicu EI,Neuhaus P,Sehouli J

更新日期：2012-10-01 00:00:00

abstract：:The effect of retinoid induced suppression of in vitro invasive ability of A549 human lung carcinoma cells on sialyltransferase activity and sialic acid content was investigated. Inhibition by retinol acetate of cell invasive potential was accompanied by a significant decrease in the enzyme activity of intact cells as...

journal_title：Anticancer research

authors： Ledinko N,Fazely F

更新日期：1989-11-01 00:00:00

abstract：:The role of growth factors in tumour growth and progression has increasingly been studied over the last few years. This review summarizes the available data and discusses their limitations as well as their potential influence on future therapeutic strategies. A large body of data suggests an important role of EGF, TGF...

journal_title：Anticancer research

authors： Nieder C,Schlegel J,Andratschke N,Thamm R,Grosu AL,Molls M

更新日期：2003-03-01 00:00:00

abstract：:We have previously reported that polaprezinc in sodium alginate suspension (P-AG) inhibited the incidence of oral mucositis induced by radiochemotherapy in patients with head and neck cancer. The present study was designed to investigate whether P-AG prevents oral mucositis in all patients (36 patients) with hematolog...

journal_title：Anticancer research

authors： Hayashi H,Kobayashi R,Suzuki A,Ishihara M,Nakamura N,Kitagawa J,Kanemura N,Kasahara S,Kitaichi K,Hara T,Tsurumi H,Moriwaki H,Itoh Y

更新日期：2014-12-01 00:00:00

abstract：:Adjuvant radioimmunotherapy (RIT) for human colonic cancer was performed in a nude rat model of experimental liver metastases. Thirty-three rats were injected intraportally through a mesenteric vein with 5 x 10(6) cells from the human colonic cancer cell line LS174T. Within half an hour, 20 MBq (n = 2), 75 MBq (n = 5)...

journal_title：Anticancer research

authors： Mahteme H,Lövqvist A,Graf W,Lundqvist H,Carlsson J,Sundin A

更新日期：1998-03-01 00:00:00

abstract：:p63 expression was evaluated in a tissue microarray of prostate tissues including benign glands, prostatic intraepithelial neoplasia and prostatic carcinoma. Immunostaining with anti-p63 antibody was restricted to basal cell nuclei. Detectable p63 was found in immortalized and early passage cell cultures, but not in s...

journal_title：Anticancer research

authors： Davis LD,Zhang W,Merseburger A,Young D,Xu L,Rhim JS,Moul JW,Srivastava S,Sesterhenn IA

更新日期：2002-11-01 00:00:00

abstract：:Complementary antitumor treatments are required to increase the cure rate achieved by surgery and/or radiotherapy by avoiding future recurrences and metastases. The growth of most solid tumors, particularly carcinomas, depends upon the simultaneous development of internal tumor vasculature to allow the proliferation o...

journal_title：Anticancer research

authors： Madarnas P,Benrezzak O,Nigam VN

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND/AIM:To investigate the outcomes of laparoscopic surgery in colorectal cancer patients with dialysis. PATIENTS AND METHODS:Fourteen dialysis (dialysis group) and 567 non-dialysis (non-dialysis group) patients who underwent laparoscopic and open surgery for colorectal cancer between April 2008 and December 20...

journal_title：Anticancer research

authors： Higashino N,Matsuda T,Hasegawa H,Yamashita K,Sakamoto H,Fujikawa M,Yamamoto M,Kanaji S,Oshikiri T,Nakamura T,Suzuki S,Kakeji Y

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND/AIM:Silica nanoparticles (nano-SiO2) are widely used in many industrial areas and there is much controversy surrounding cytotoxic effects of such nanoparticles. In order to determine the toxicity and possible molecular mechanisms involved, we conducted several tests with two breast cancer cell lines, MDA-MB-...

journal_title：Anticancer research

authors： Jeon D,Kim H,Nam K,Oh S,Son SH,Shin I

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Canine lymphoma has lately drawn focus as a model of human non-Hodgkin's lymphoma due to its spontaneous occurrence and similar biological behavior. Cells with stem cell-like characteristics are believed to play a key role in therapeutic failure. Thus, an initial characterization and the possibility of speci...

journal_title：Anticancer research

authors： Liu W,Selçuk F,Rütgen BC,Moulay M,Willenbrock S,Hammer SE,Sterenczak KA,Junghanss C,Hewicker-Trautwein M,Nolte I,Murua Escobar H

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND/AIM:In the present article we review on the use of Volumetric Modulated Arc Therapy (VMAT) for a small lung nodule that was centrally located in close proximity to the mediastinal structures. CASE REPORT:An inoperable patient with central, clinical stage IA adenocarcinoma of the right lung was treated with ...

journal_title：Anticancer research

authors： Valakh V,Chan P,D'Adamo K,Micaily B

更新日期：2013-10-01 00:00:00

abstract：:The effect of 4,6-benzylidene-D-glucose (BG) on chemically induced primary hepatocellular carcinomas in rats was tested after daily single injections of 85 mg per kg body weight into the aorta through a canula implanted through the right carotid artery. Treatment started immediately following a biopsy confirming the d...

journal_title：Anticancer research

authors： Pettersen EO,Schwarze PE,Dornish JM,Nesland JM

更新日期：1986-03-01 00:00:00

abstract：AIM:Metabolic syndrome has been identified as a risk factor for colorectal cancer and adenoma. The aim of our study was to assess the risk of colorectal cancer and adenoma in an adult Italian population with metabolic syndrome. PATIENTS AND METHODS:Ninety patients with metabolic syndrome were prospectively compared ag...

journal_title：Anticancer research

authors： Fiori E,Lamazza A,De Masi E,Schillaci A,Crocetti D,Antoniozzi A,Sterpetti AV,De Toma G

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Dihydroceramide desaturase 1 (DES) is the enzyme responsible for converting dihydroceramide into ceramide in the de novo sphingolipid biosynthesis pathway. Dihydroceramide can inhibit ceramide channel formation to interfere with apoptosis. We have shown that following ceramide synthase knockdown, photodynami...

journal_title：Anticancer research

authors： Breen P,Joseph N,Thompson K,Kraveka JM,Gudz TI,Li L,Rahmaniyan M,Bielawski J,Pierce JS,VAN Buren E,Bhatti G,Separovic D

更新日期：2013-01-01 00:00:00

abstract：:Selective delivery of a high level of Mitomycin C (MMC) in intraperitoneal disseminated lesions was studied using a new dosage form of MMC, called MMC-CH. Intracavitary MMC-CH delivered a much higher level of MMC selectively to intraperitoneal tissues, with a much lower level of MMC in the whole body, in comparison wi...

journal_title：Anticancer research

authors： Hagiwara A,Takahashi T,Lee R,Ueda T,Takeda M,Itoh T

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND/AIM:High expression of the Bcl-2-interacting cell death suppressor (BIS), an anti-apoptotic protein, in various human cancers is linked to a poor outcome. The purpose of this study was to clarify whether BIS is associated with the migration and invasive characteristics of A549 cells. MATERIALS AND METHODS:B...

journal_title：Anticancer research

authors： Lee J,Yun HH,Kim S,Ji SH,Kuh HJ,Lee JH

更新日期：2018-09-01 00:00:00

abstract：:Immunocytochemical assays were performed on frozen sections of inflammatory breast carcinomas (n = 22) using the following monoclonal antibodies (MoAb): anti-pHER2/neu, cathepsin, pS2, ER, PR and MoAb Ki67. The distribution of these proteins, known as prognostic indicators, was evaluated with an image analysis system ...

journal_title：Anticancer research

authors： Charpin C,Bonnier P,Khouzami A,Vacheret H,Andrac L,Lavaut MN,Allasia C,Piana L

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND/AIM:Lymphatic invasion (ly) may mainly reflect the selective affinity of breast cancer cells for lymph nodes. We conducted the present study to investigate whether the presence of lymphatic invasion is a predictor of sentinel lymph node (SLN) metastasis in clinically node-negative breast cancer. PATIENTS AN...

journal_title：Anticancer research

authors： Fujii T,Yajima R,Tatsuki H,Suto T,Morita H,Tsutsumi S,Kuwano H

更新日期：2015-06-01 00:00:00

abstract：:The antibacterial agent taurolidine (TRD) has been used as a lavage antibiotic to prevent development of peritonitis in patients after surgery. We recently showed that TRD induced growth arrest and apoptosis of a variety of cultured cell lines derived from human solid tumors and also significantly inhibited the growth...

journal_title：Anticancer research

authors： Han Z,Ribbizi I,Pantazis P,Wyche J,Darnowski J,Calabresi P

更新日期：2002-07-01 00:00:00

abstract：AIM:To evaluate the role of radiotherapy alone or combined with chemotherapy in the treatment of recurrent vulvar cancer, emphasising the prognostic factors and outcomes. MATERIALS AND METHODS:Twenty women with loco-regional recurrence of vulvar carcinoma were retrospectively reviewed. Eleven patients were managed wit...

journal_title：Anticancer research

authors： Raffetto N,Tombolini V,Santarelli M,Valeriani M,Galla DA,Enrici RM

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:An acidic arabinogalactan from European mistletoe (Viscum album L, VAL; 1.34 x 10(6) Dalton) was studied in detail because its immunological properties are poorly characterised. MATERIALS AND METHODS:Flow cytometric studies focussed on PS-activated proliferation of human lymphocytes measured via incorporati...

journal_title：Anticancer research

authors： Stein GM,Edlund U,Pfüller U,Büssing A,Schietzel M

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Early detection before scintigraphic appearance of osseous metastatic spread might improve the outcome of breast cancer patients. The amino-terminal propeptide (PINP) of type I collagen as an indicator of bone formation is a very promising candidate among all markers of bone metabolism. We investigated the u...

journal_title：Anticancer research

authors： Lüftner D,Jozereau D,Schildhauer S,Geppert R,Müller C,Fiolka G,Wernecke KD,Possinger K

更新日期：2005-05-01 00:00:00

abstract：AIM:We aimed to clarify the prognostic significance of HER2 positivity in advanced gastric cancer. PATIENTS AND METHODS:The cohort included patients with initially metastatic or recurrent gastric cancer treated with first-line modified FOLFOX-6. The HER2 status was analyzed according to modified scoring criteria speci...

journal_title：Anticancer research

authors： Kim JW,Im SA,Kim M,Cha Y,Lee KH,Keam B,Kim MA,Han SW,Oh DY,Kim TY,Kim WH,Bang YJ

更新日期：2012-04-01 00:00:00

abstract：:Tissue inhibitor of metalloproteinase-1 (TIMP-1) is a major endogenous regulator of matrix metalloproteinases. This study examined the relation between TIMP-1 gene expression and postoperative mortality in patients with colorectal cancer (CRC). Specimens of CRC were obtained from 202 patients. The relative expression ...

journal_title：Anticancer research

authors： Inagaki D,Oshima T,Yoshihara K,Tamura S,Kanazawa A,Yamada T,Yamamoto N,Sato T,Shiozawa M,Morinaga S,Akaike M,Fujii S,Numata K,Kunisaki C,Rino Y,Tanaka K,Masuda M,Imada T

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Women with recurrent ovarian cancer have a poor prognosis and short survival. However, some women are long-term survivors and it is unclear whether they share specific common characteristics. CASE REPORT:We present the case of a 63-year-old woman with histologically-proven recurrent ovarian cancer and a sur...

journal_title：Anticancer research

authors： Hilal Z,Schultheis B,Hartmann F,Dogan A,Cetin C,Krentel H,Schiermeier S,Tempfer CB

更新日期：2016-10-01 00:00:00

abstract：:Inv(3)(q21q26)/t(3;3)(q21;q26) is a feature of a distinctive entity of acute myeloid leukemia (AML) associated with normal or elevated platelet count, atypical megakaryocytes and multilineage dysplasia in the bone marrow, as well as minimal to no response to chemotherapy and poor clinical outcome. The presence of an i...

journal_title：Anticancer research

authors： De Braekeleer E,Douet-Guilbert N,Le Bris MJ,Ianotto JC,Berthou C,Gueganic N,Bovo C,Basinko A,Morel F,De Braekeleer M

更新日期：2013-02-01 00:00:00

abstract：:The neurogenic rat tumour BT4A was serially transplanted to the dorsum of the right hind leg of BD IX rats. The tumours were treated with water bath heating at 44.0 degrees C for one hour alone or combined with bleomycin or BCNU, both given intraperitoneally at a dose of 20 mg/kg. Bleomycin alone had no effect on tumo...

journal_title：Anticancer research

authors： Dahl O,Mella O

更新日期：1982-11-01 00:00:00