Limited transfer of prostaglandin E2 across the fetal membrane before and after labor.

Abstract:

:The transfer of prostaglandin E2 (PGE2) across intact fetal membranes (amnion-chorion-decidua) obtained before and after the onset of labor was investigated using a novel system for in vitro fetal membrane culture. Studies using physiological concentrations of PGE2 showed that very little PGE2 will cross the membranes without being metabolised, before or after the onset of labor. It was only when pharmacological concentrations of PGE2 were used that the enzyme activity of the chorion was no longer able to prevent transfer of PGE2 without conversion to inactive metabolites. These results suggest that only small amounts of PGE2 from amnion are normally transferred across the chorio-decidua before or after the onset of labor, but the metabolism of PGE2 subsequent to transfer across the fetal membranes requires further assessment.

authors

Roseblade CK,Sullivan MH,Khan H,Lumb MR,Elder MG

doi

10.3109/00016349009013301

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

399-403

issue

5

eissn

0001-6349

issn

1600-0412

journal_volume

69

pub_type

杂志文章
  • The effects of reducing the thermal index for bone from 1.0 to 0.5 and 0.1 on common obstetric pulsed wave Doppler measurements in the second half of pregnancy.

    abstract:OBJECTIVE:To test the hypothesis that clinically relevant vessels can be visualized and interrogated with Doppler recording during the second half of pregnancy at an output energy below the currently advocated limits without loss of information. DESIGN:Observational cross-sectional study. SETTING:Tertiary fetal medic...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/aogs.12114

    authors: Sande RK,Matre K,Eide GE,Kiserud T

    更新日期:2013-07-01 00:00:00

  • A health care program for the investigation and treatment of elderly women with urinary incontinence and related urogenital symptoms.

    abstract::The assessment and treatment of urinary incontinence and related urogenital symptoms using an algorithm model was evaluated in 364 elderly women complaining of urinary incontinence. The women (age 72.1 +/- 1.5 years, range 65-84 years) were assessed by a 48-hour pad test, a cough provocation test, micturition lists an...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349109006196

    authors: Molander U,Milsom I,Ekelund P,Arvidsson L,Eriksson O

    更新日期:1991-01-01 00:00:00

  • Does resilience moderate the effect of intimate partner violence on signs of depression among Tanzanian pregnant women: A cross-sectional study.

    abstract:INTRODUCTION:Exposure to intimate partner violence (IPV) has been found to be associated with a multitude of poor health and quality of life outcomes. Among the risks exacerbated by IPV is prenatal depression. Resilience is hypothesized to protect against psychopathology after exposure to a traumatic influence. The pre...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.14062

    authors: Magnusson FL,Rogathi JJ,Sigalla GN,Manongi R,Rasch V,Gammeltoft T,Meyrowitsch DW

    更新日期:2020-12-14 00:00:00

  • Serum CA 125 levels in patients with a provisional diagnosis of pelvic inflammatory disease. Clinical and theoretical implications.

    abstract::In 50 patients with a provisional diagnosis of pelvic inflammatory disease (PID), CA 125 concentrations in serum were measured before laparoscopy and during hospitalization, using an enzyme immunoassay. The findings at laparoscopy were graded on the basis of the extent of inflammatory peritoneal involvement (grades 0-...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348909013284

    authors: Duk JM,Kauer FM,Fleuren GJ,de Bruijn HW

    更新日期:1989-01-01 00:00:00

  • Disclosing doubtful indications for emergency cesarean sections in rural hospitals in Tanzania: a retrospective criterion-based audit.

    abstract:OBJECTIVE:To investigate in depth to what extent indications for emergency cesarean sections followed evidence-based audit criteria for realistic best practice. DESIGN:A quality assurance analysis based on a retrospective criterion-based audit. SETTING:Two rural hospitals in Tanzania. POPULATION:From 2009, 400 cesar...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0412.2012.01474.x

    authors: Maaløe N,Bygbjerg IC,Onesmo R,Secher NJ,Sorensen BL

    更新日期:2012-09-01 00:00:00

  • Treatment of vulvovaginal erosive and stenosing lichen planus by surgical dilatation and methotrexate.

    abstract::We treated five patients with stenosing lichen planus [LP] of the vulvovaginal region with methotrexate supplemented with ultrapotent corticosteroid cream and tacrolimus, in combination with surgical dilatation. All patients experienced long-term symptom relief, and there was only minimal or moderate re-stenosing of t...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016340601110721

    authors: Kortekangas-Savolainen O,Kiilholma P

    更新日期:2007-01-01 00:00:00

  • Prenatal diagnosis of omphalocele associated with umbilical cord cyst.

    abstract:BACKGROUND:To study the cytogenetics, ultrasound findings, biochemical screening, perinatal outcome, and associated abnormalities in cases of omphaloceles associated with umbilical cord cysts. METHODS:From 1988 to 1994, three cases of omphaloceles with umbilical cord cysts were identified at Mackay Memorial Hospital. ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349509021207

    authors: Chen CP,Jan SW,Liu FF,Chiang S,Huang SH,Sheu JC,Wang KG,Lan CC

    更新日期:1995-11-01 00:00:00

  • No effect of vitamin B-6 against premenstrual tension. A controlled clinical study.

    abstract::Vitamin B-6 100 mg given daily throughout the menstrual cycle was compared with placebo in a randomized, double-blind crossover trial in 34 women who suffered from premenstrual tension. Vitamin B-6 was no better than placebo. There was a substantial period effect, as the women evidenced a considerable preference for t...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00016348509158211

    authors: Hagen I,Nesheim BI,Tuntland T

    更新日期:1985-01-01 00:00:00

  • Treatment of urinary tract infections in gynecological patients. A randomized study comparing pivampicillin-pivmecillinam with trimethoprim-sulphamethoxazole.

    abstract::Eighty-two gynecological patients with clinical signs of a lower urinary tract infection (UTI) were randomized to 10 days' treatment with either a fixed combination of pivampicillin-pivmecillinam (PAPM) or trimethoprim-sulphamethoxazole (TMPS). The effect of treatment could be evaluated in 25 patients on PAPM and in 1...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00016348309154228

    authors: Iosif CS,Laurin J,Möller EB,Bauer CA

    更新日期:1983-01-01 00:00:00

  • Anal incontinence after obstetric sphincter tears: incidence in a Norwegian county.

    abstract:BACKGROUND:Anal sphincter tears during vaginal delivery are a major cause of anal incontinence. We wanted to assess the incidence in a Norwegian county where primary repairs are performed in four hospitals using similar per- and postoperative protocol for the treatment of such injuries. METHODS:A postal questionnaire ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-6349.2004.00647.x

    authors: Norderval S,Nsubuga D,Bjelke C,Frasunek J,Myklebust I,Vonen B

    更新日期:2004-10-01 00:00:00

  • Total intra-uterine volume and symphysis fundus height. Is there a relation?

    abstract::The concordance between measurements of total intra-uterine volume (parallel planimetric area method) and symphysis fundus height and the efficacy of these measurements in predicting birthweight by centile range was prospectively investigated in a blind study of 81 measurement sets in 74 women in the third trimester o...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348709103650

    authors: Geirsson RT,Agustsson P

    更新日期:1987-01-01 00:00:00

  • Reducing stillbirths in low-income countries.

    abstract::Worldwide, 98% of stillbirths occur in low-income countries (LIC), where stillbirth rates are ten-fold higher than in high-income countries (HIC). Although most HIC stillbirths occur prenatally, in LIC most stillbirths occur at term and during labor/delivery. Conditions causing stillbirths include those of maternal or...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.12817

    authors: Goldenberg RL,Saleem S,Pasha O,Harrison MS,Mcclure EM

    更新日期:2016-02-01 00:00:00

  • Perceptions, outcomes, and regret following social egg freezing in the UK; a cross-sectional survey.

    abstract:INTRODUCTION:Social egg freezing enhances reproductive autonomy by empowering women with the capacity to delay their childbearing years, while preserving the opportunity to maintain biological relation with subsequent offspring. However, age-related obstetric complications, economic implications and the risk of unsucce...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13763

    authors: Jones BP,Kasaven L,L'Heveder A,Jalmbrant M,Green J,Makki M,Odia R,Norris G,Bracewell Milnes T,Saso S,Serhal P,Ben Nagi J

    更新日期:2020-03-01 00:00:00

  • The relation between urinary incontinence and steroid hormone levels in perimenopausal women. A report from the Women's Health in the Lund Area (WHILA) study.

    abstract:OBJECTIVE:To outline possible associations between urinary incontinence (UI) and serum levels of steroid hormones in middle-aged women. DESIGN AND SETTING:Community-based observational study. SAMPLE:All women aged 50-59 living in the Lund area by December 1995 were invited to a screening procedure. Sixty-four percent...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016340903117986

    authors: Teleman PM,Persson J,Mattiasson A,Samsioe G

    更新日期:2009-01-01 00:00:00

  • Comparison of ultrasonography, hysteroscopy, and biopsy in the diagnosis of endometrial lesions in postmenopausal tamoxifen-treated patients.

    abstract:BACKGROUND:At present, no proven recommendations can be made for the surveillance of tamoxifen-treated women. The aim of the present study was to evaluate ultrasonography and hysteroscopy in this setting. METHODS:Three hundred and ten postmenopausal patients using tamoxifen underwent vaginal ultrasonography, hysterosc...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1034/j.1600-0412.2002.811013.x

    authors: Giorda G,Crivellari D,Veronesi A,Perin T,Campagnutta E,Carbone A,Scarabelli C

    更新日期:2002-10-01 00:00:00

  • Laparoscopy versus culdoscopy in the investigation of infertility.

    abstract::This retrospective analysis compares laparoscopy versus culdoscopy results in the investigation of infertility. 52 women underwent culdoscopy; 49 women underwent laparoscopy. Then a change in method was made due to the acquisition of a cold-light laparoscopy. A third group of 73 women were examined with the new ins...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016347409156901

    authors: Fredricsson B

    更新日期:1974-01-01 00:00:00

  • Deprived neighborhoods and adverse perinatal outcome: a systematic review and meta-analysis.

    abstract:OBJECTIVES:This study aims to summarize evidence on the relation between neighborhood deprivation and the risks for preterm birth, small-for-gestational age, and stillbirth. DESIGN:The design was a systematic review and meta-analysis. MAIN OUTCOME MEASURES:The main outcome measures included studies that directly comp...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/aogs.12430

    authors: Vos AA,Posthumus AG,Bonsel GJ,Steegers EA,Denktaş S

    更新日期:2014-08-01 00:00:00

  • Bone turnover from early pregnancy to postweaning.

    abstract:BACKGROUND:To elucidate the sequences of changes in bone metabolism and bone density during pregnancy, lactation and postweaning. METHODS:Women were recruited (n = 254) in early pregnancy and followed for 2 years. Markers of bone formation (osteocalcin) and resorption (NTx) were measured at five occasions. Bone minera...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-6349.2004.00428.x

    authors: Akesson A,Vahter M,Berglund M,Eklöf T,Bremme K,Bjellerup P

    更新日期:2004-11-01 00:00:00

  • Intrapartum influences on cesarean delivery in multiple gestation.

    abstract:OBJECTIVE:To evaluate which intrapartum factors influence the method of delivery in a group of twin pregnancies eligible for vaginal delivery. STUDY DESIGN:Over a 10-year period, 967 consecutive twin pregnancies at gestational age >/=32 weeks with twin A presenting as a vertex and eligible for vaginal delivery were re...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0412.2003.00098.x

    authors: Williams KP,Galerneau F

    更新日期:2003-03-01 00:00:00

  • Prenatal diagnosis of autosomal recessive polycystic kidney disease by ultrasonography and magnetic resonance imaging.

    abstract::Autosomal recessive polycystic kidney disease is a relatively rare congenital disease affecting the kidneys and liver. We noticed the kidney abnormality at 22 weeks gestation and observed the patient till the delivery at 36 weeks of gestation. The ultrasonographic features consisted of bilaterally enlarged hyperechoge...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349109007927

    authors: Nishi T,Iwasaki M,Yamoto M,Nakano R

    更新日期:1991-01-01 00:00:00

  • Hypertensive disorders in pregnancy and later dementia: a Swedish National Register Study.

    abstract:INTRODUCTION:Our aim was to investigate the rate of vascular dementia and dementia in women with previous hypertensive disorders in pregnancy, since white matter lesions of the brain and cardiovascular disease are linked both to dementia and hypertensive disorders in pregnancy. MATERIAL AND METHODS:Prospective populat...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13096

    authors: Andolf EG,Sydsjö GC,Bladh MK,Berg G,Sharma S

    更新日期:2017-04-01 00:00:00

  • Management of placenta accreta.

    abstract::Cesarean hysterectomy is considered the reference standard treatment for placenta accreta. In young women who want the option of future pregnancy and agree to close follow-up monitoring, conservative treatment is a valid option. Several key points of both cesarean hysterectomy and conservative treatment remain debatab...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/aogs.12222

    authors: Sentilhes L,Goffinet F,Kayem G

    更新日期:2013-10-01 00:00:00

  • Risk of spontaneous abortion following legally induced abortion.

    abstract::Using the registration of all pregnant women living within a particular geographical district of Copenhagen the risk of spontaneous abortion has been calculated by means of a decremental method. A total of 3,042 pregnancies were registered and the total risk of spontaneous abortion was calculated at 10 per cent. In 43...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348009154629

    authors: Obel EB

    更新日期:1980-01-01 00:00:00

  • Placental abruption. Maternal risk factors and associated fetal conditions.

    abstract:OBJECTIVE:To investigate maternal risk factors and fetal conditions associated with abruption. METHODS:Prospective cohort study of 30,681 singleton pregnancies at least 28 weeks' gestation. Data collected by patient questionnaire at the first prenatal visit and by medical record review. RESULTS:307 women had abruptio...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349309021156

    authors: Raymond EG,Mills JL

    更新日期:1993-11-01 00:00:00

  • Changing concepts of medical treatment of endometriosis.

    abstract::Studies on the natural history of endometriosis have demonstrated that the majority of endometriosis implants tend to progress, a finding that indicates eradication of the lesions by medical and/or surgical approaches. Infertility and dysmenorrhea are other indications for medical therapy in this disease. In recent pr...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.3109/00016349309021107

    authors: Kauppila A

    更新日期:1993-07-01 00:00:00

  • Maternal and neonatal outcomes of large for gestational age pregnancies.

    abstract:OBJECTIVE:To compare maternal and neonatal outcomes of term large for gestational age (LGA) pregnancies and adequate for gestational age (AGA) pregnancies. DESIGN:Retrospective analysis. SETTING:Large university research medical center. POPULATION:All term singleton LGA (birthweight ≥ 90th percentile) and AGA pregna...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0412.2012.01412.x

    authors: Weissmann-Brenner A,Simchen MJ,Zilberberg E,Kalter A,Weisz B,Achiron R,Dulitzky M

    更新日期:2012-07-01 00:00:00

  • Cardiotocography supplemented with continuous fetal pH monitoring during labor. Effect on rate of obstetrical interventions and neonatal condition.

    abstract::Continuous monitoring of the fetal scalp tissue pH (tpH) was performed in 96 consecutive cases. Of these 96, 72 (75%) had acceptable pH tracings which were used for the management of labor (series II). These 72 patients were compared with 72 patients from an earlier series (series I) of tpH monitoring in which pH was ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Weber T

    更新日期:1982-01-01 00:00:00

  • Maternal and neonatal outcomes of pregnancy in women with chronic hypertension: a retrospective analysis of a national register.

    abstract:INTRODUCTION:Pregnancies complicated by chronic hypertension are at increased risk of adverse pregnancy outcomes. To assess whether planned early delivery might prevent some of these adverse outcomes, we studied maternal and neonatal outcomes of pregnancy in women with chronic hypertension, including gestational-age-sp...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.12757

    authors: Broekhuijsen K,Ravelli AC,Langenveld J,van Pampus MG,van den Berg PP,Mol BW,Franssen MT

    更新日期:2015-12-01 00:00:00

  • Difficulties in the antenatal assessment of neonatal alloimmune thrombocytopenia.

    abstract::In this paper we present a patient with an initially questionable history of neonatal alloimmune thrombocytopenia (NAT) due to materno-fetal HPA-1a (PLA1) incompatibility. No circulating antibodies were detectable in untreated maternal serum, but an adsorption/elution technique enabled the demonstration of the platele...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349309058169

    authors: Marzusch K,Fischer J,Dietl J,Wiest E,Völklein K,Schnaidt M

    更新日期:1993-10-01 00:00:00

  • Screening voided urine for Chlamydia trachomatis in asymptomatic adolescent females.

    abstract::First catch urine (FCU) from 751 asymptomatic adolescent female high school students, with sexual debut, were screened for the presence of Chlamydia trachomatis (Group A). The prevalence of C. trachomatis infection in Group A was 2.1% (16/751). In Group B, 619 asymptomatic adolescent females attending a youth and a fa...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349409013397

    authors: Svensson LO,Mares I,Mårdh PA,Olsson SE

    更新日期:1994-01-01 00:00:00