Quality of life in patients with multiple sclerosis in Eastern Slovakia.

Abstract:

PURPOSE:Quality of life (QoL) is an important measure of the burden of disease and could be useful in evaluating patient management and practical interventions. The aim of this study was to explore the association of psychological and clinical variables with QoL in patients with multiple sclerosis (MS). METHODS:One hundred and fourteen consecutive patients (mean age 36.1 ± 10.3 years, 72% female) from one MS centre completed the Hospital Anxiety and Depression Scale, the Fatigue Severity Scale and the Short-Form-36 Health Survey (SF-36). Functional disability was assessed using the Expanded Disability Status Scale. Multiple linear regression analyses were performed to analyse demographic, psychological and clinical data. RESULTS:Functional disability, depression and fatigue were found to be related inversely to the physical health subscale. Disease course, anxiety and depression were associated negatively with the mental health subscale. CONCLUSIONS:Functional disability, depression and fatigue were the main variables related to the perceived physical health subscale, and disease course, anxiety and depression to the perceived mental health subscale in the group of patients with MS. Thus, effective treatment of fatigue, anxiety and depression could be assumed to increase a patient's QoL.

journal_name

Disabil Rehabil

authors

Szilasiova J,Krokavcova M,Gdovinova Z,Rosenberger J,Van Dijk JP

doi

10.3109/09638288.2010.540292

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

1587-93

issue

17-18

eissn

0963-8288

issn

1464-5165

journal_volume

33

pub_type

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