Antibiotic prophylaxis in the placement of totally implanted central venous access ports.

Abstract:

BACKGROUND:Antibiotic prophylaxis during placement of implanted central venous access ports (CVAP) has not been studied. This retrospective review compared the rate of catheter-related infections (CRIs) with and without perioperative antibiotics. METHODS:This was a single-center study that compared patients treated with and without a single dose of antibiotics during CVAP placement. CRIs were defined as a patient treated with antibiotics for port site induration, positive blood cultures, or suspicion of infection that led to port removal within 30 days of placement. RESULTS:CVAP were placed in 459 patients, 103 of whom (22.4%) received antibiotic prophylaxis. Surgical technique and patient demographics were similar to those patients not receiving antibiotics (356). All 9 (2%) CRIs occurred in the non-prophylactic antibiotic group (P = .218), with 5 infections resulting in port removal. CONCLUSIONS:Single-dose perioperative antibiotics may decrease CVAP infection rates and should be studied further in a prospective randomized trial.

journal_name

Am J Surg

authors

Scaife CL,Gross ME,Mone MC,Hansen HJ,Litz CL,Nelson ET,Anderson CJ,Wagner G,Gawlick U,Nelson EW

doi

10.1016/j.amjsurg.2010.07.023

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

719-22; disussion 722-3

issue

6

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(10)00524-6

journal_volume

200

pub_type

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