Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2'-deoxyuridines.

Abstract:

:We have focused on the C5-modification of 2'-deoxyuridine with substituted heterocycles for bioactivity, such as antiviral or anticancer activity. Herein, we report a novel class of nucleoside analogues with perfluoroalkyltriazole moiety as an anticancer drug candidate.

journal_name

Bioorg Med Chem Lett

authors

Park SM,Yang H,Park SK,Kim HM,Kim BH

doi

10.1016/j.bmcl.2010.07.126

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

5831-4

issue

19

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(10)01095-4

journal_volume

20

pub_type

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