Secondary acute lymphoblastic leukaemia with 4:11 translocation following treatment for Hodgkin's disease: case report and review of the literature.

Abstract:

:It is apparent that treatment of Hodgkin's disease can be complicated by the development of secondary leukaemia. Most such leukaemias are of the non-lymphocytic type. We describe here a patient treated for Hodgkin's disease with chemo- and radiotherapy who developed secondary acute lymphoblastic leukaemia with a non-random chromosomal abnormality t(4;11). The frequency of such cases is assessed by a literature review and evidence for their pluripotent cell origin is discussed.

journal_name

Leukemia

journal_title

Leukemia

authors

Lennard A,Jackson GH,Carey PJ,Bown N,Middleton P,Proctor SJ

subject

Has Abstract

pub_date

1991-07-01 00:00:00

pages

624-7

issue

7

eissn

0887-6924

issn

1476-5551

journal_volume

5

pub_type

杂志文章,评审

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