Abstract:
:It is apparent that treatment of Hodgkin's disease can be complicated by the development of secondary leukaemia. Most such leukaemias are of the non-lymphocytic type. We describe here a patient treated for Hodgkin's disease with chemo- and radiotherapy who developed secondary acute lymphoblastic leukaemia with a non-random chromosomal abnormality t(4;11). The frequency of such cases is assessed by a literature review and evidence for their pluripotent cell origin is discussed.
journal_name
Leukemiajournal_title
Leukemiaauthors
Lennard A,Jackson GH,Carey PJ,Bown N,Middleton P,Proctor SJsubject
Has Abstractpub_date
1991-07-01 00:00:00pages
624-7issue
7eissn
0887-6924issn
1476-5551journal_volume
5pub_type
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