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Perioperative management of a patient with hereditary angioedema during off-pump coronary artery bypass graft surgery.

Abstract：

:The case of a patient with hereditary angioedema (HAE), a rare, life-threatening disorder caused by reduced activity of the C1 esterase inhibitor, and requiring off-pump coronary artery bypass graft (OP-CABG) surgery, is presented. Perioperative management of patients with HAE who undergo complex cardiac surgical procedures are discussed, including an OP-CABG surgical approach to decrease complement activation, fresh-frozen plasma administration to increase C1 esterase inhibitor activity, and administration of reduced doses of heparin and protamine to minimize heparin-protamine complex formation.

journal_name

J Clin Anesth

journal_title

Journal of clinical anesthesia

authors

Shick V,Sanchala V,McGoldrick KE,Tartaglia JJ,Nelson J,Fleisher AJ

doi

10.1016/j.jclinane.2009.04.007

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

282-4

issue

4

eissn

0952-8180

issn

1873-4529

pii

S0952-8180(10)00128-5

journal_volume

22

pub_type

杂志文章

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