Infant neurobehavior following prenatal exposure to methadone or buprenorphine: results from the neonatal intensive care unit network neurobehavioral scale.

Abstract:

:This study examined the neurobehavioral functioning of neonates prenatally exposed to methadone (n = 11) or buprenorphine (n = 10), who underwent the Neonatal Intensive Care Unit Network Neurobehavioral Scale (NNNS) examinations on days 3, 5, 7, 10, and 14 post-delivery. Linear mixed model analyses revealed that NNNS scores of arousal and excitability showed significant differences between medications over time. Compared to neonates who did not require medication to treat neonatal abstinence syndrome (NAS), neonates receiving pharmacotherapy for NAS showed differences over time in quality of movement, excitability, and lethargy. Results suggest the NNNS may detect subtle differences over time between both neonates prenatally exposed to methadone or buprenorphine and neonates pharmacologically treated or untreated for NAS.

journal_name

Subst Use Misuse

journal_title

Substance use & misuse

authors

Jones HE,O'Grady KE,Johnson RE,Velez M,Jansson LM

doi

10.3109/10826084.2010.484474

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

2244-57

issue

13

eissn

1082-6084

issn

1532-2491

journal_volume

45

pub_type

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