Abstract:
OBJECTIVE:To compare the treatment and follow-up of patients with lichen sclerosus (LS) at the departments of Gynaecology and Dermatology at the Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands, to evaluate the need for a multidisciplinary vulvar clinic. MATERIALS AND METHODS:Treatment and follow-up data of all women with histologically proven (between January 1995 and January 2001) anogenital LS visiting the outpatient clinics of the departments of Obstetrics & Gynaecology and Dermatology were collected (last date of follow-up: January 2008). RESULTS:Eighty-four patients with LS were included in this study, 10 patients (12%) of which were treated by both specialties. At the Gynaecology department, LS patients more often received surgical treatment, topical estrogens, and lidocaine ointment, whereas at the Dermatology department, local class 2/3 corticosteroids were more often prescribed. Follow-up frequencies were similar in both specialties and took place at 3 to 4 visits in the first year and at least once a year afterward. One patient developed vulvar squamous cell carcinoma. This patient had withdrawn from follow-up and had her condition diagnosed with carcinoma 74 months after the LS had been diagnosed. CONCLUSIONS:Although no hospital guidelines existed, management of patients with LS agreed with current recommendations in the literature, although differences in secondary and supportive therapy existed owing to differences in expertise. The relatively high percentage of patients treated by both specialties with a high frequency of visits emphasizes the need for a multidisciplinary clinic for vulvar disease.
journal_name
J Low Genit Tract Disjournal_title
Journal of lower genital tract diseaseauthors
van der Avoort IA,Tiemes DE,van Rossum MM,van der Vleuten CJ,Massuger LF,de Hullu JAdoi
10.1097/LGT.0b013e3181c4bfe6subject
Has Abstractpub_date
2010-04-01 00:00:00pages
118-23issue
2eissn
1089-2591issn
1526-0976pii
00128360-201004000-00007journal_volume
14pub_type
杂志文章abstract:OBJECTIVES:To determine whether there is an association between high levels of telomerase and premalignant cervical disease and to provide a preliminary analysis of telomerase activity as a potential triage strategy. MATERIALS AND METHODS:Premenopausal women were invited to participate in the study during routine gyne...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/00128360-200504000-00005
更新日期:2005-04-01 00:00:00
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journal_title:Journal of lower genital tract disease
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doi:10.1097/LGT.0b013e3181ed3d6d
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abstract:OBJECTIVE:This study aimed to assess the incidence of cervical intraepithelial neoplasia (CIN) by grade (CIN 1, CIN 2, CIN 3) and age in Estonia (a country with less developed cervical cancer screening program and high cervical cancer incidence). MATERIALS AND METHODS:This descriptive study uses data from a health ins...
journal_title:Journal of lower genital tract disease
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abstract:OBJECTIVE:In this study, we investigated whether physical inactivity was associated with risk of cervical cancer in women treated at an American cancer hospital. METHODS:This case-control study included 128 patients with cervical cancer and 512 controls matched on age. Controls were women suspected of having but not u...
journal_title:Journal of lower genital tract disease
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journal_title:Journal of lower genital tract disease
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更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:The Home Study Course is intended for the practicing colposcopist or practitioner who is seeking to develop or enhance his/her colposcopic skills. The goal of the course is to present colposcopic cases that are unusual or instructive in terms of appearance, presentation, or management, or that demonstrate new...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/lgt.0b013e3180380fd3
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journal_title:Journal of lower genital tract disease
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更新日期:2019-04-01 00:00:00
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journal_title:Journal of lower genital tract disease
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journal_title:Journal of lower genital tract disease
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journal_title:Journal of lower genital tract disease
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journal_title:Journal of lower genital tract disease
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e318259a410
更新日期:2013-01-01 00:00:00
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journal_title:Journal of lower genital tract disease
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更新日期:2018-07-01 00:00:00
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/00128360-200207000-00008
更新日期:2002-07-01 00:00:00
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
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更新日期:2011-10-01 00:00:00
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
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更新日期:2014-10-01 00:00:00
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,多中心研究
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journal_title:Journal of lower genital tract disease
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journal_title:Journal of lower genital tract disease
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
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更新日期:2011-10-01 00:00:00
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:Journal of lower genital tract disease
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journal_title:Journal of lower genital tract disease
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
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更新日期:2003-10-01 00:00:00
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e3181f0b8f5
更新日期:2011-01-01 00:00:00
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
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更新日期:2011-10-01 00:00:00
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/00128360-199710000-00008
更新日期:1997-10-01 00:00:00
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journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,多中心研究,随机对照试验
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