Abstract:
OBJECTIVE:The study aims to assess the frequency of cytological abnormalities in adolescents and young women, to establish the optimum age to start screening. METHODS:A retrospective study of cervical cytology results were obtained from the data center at the Santa Casa Hospital of São Paulo between January 2006 and December 2014, adopting the Bethesda nomenclature system. The cytology exams were divided into 3 groups: group 1-adolescents (10-19 years old); group 2-young women (20-24 years old); and group 3-adults, comprising the remaining cytology exams. The frequency of cytological abnormalities in the 3 groups was compared using version 3.4.3 of the Epi Info software program and the chi-square statistical test (p < .05). RESULTS:A total of 177,075 satisfactory cytology exams were included in the study. The cytological abnormalities detected in the adolescent group were predominantly low-grade lesions (97.4%); in the young women group, low-grade lesions represented 89.12%, and in the adult group, 76.33%. A significantly greater proportion of high-grade lesions were noted in the adult group, accounting for approximately 24% of all abnormalities detected; in the young women group, it was approximately 11%, and in the adolescent group, it was 2.6%. CONCLUSIONS:The natural history of HPV infection shows it is transient in young women, with most cases regressing within 2 years of presentation. Our data confirm that screening of adolescents is not recommended because serious cytological abnormalities and cancer are rare in this group.
journal_name
J Low Genit Tract Disjournal_title
Journal of lower genital tract diseaseauthors
Henrique LQ,Campaner AB,dʼAvila FSdoi
10.1097/LGT.0000000000000273subject
Has Abstractpub_date
2017-01-01 00:00:00pages
21-25issue
1eissn
1089-2591issn
1526-0976pii
00128360-201701000-00006journal_volume
21pub_type
杂志文章abstract:OBJECTIVE:The purpose of this study was to demonstrate a methodology for auditing the impact of HCII testing on the direct cost of cervical cancer cytological screening, where the test is collected in all women screened and processed routinely in women age 30 years and older. MATERIALS AND METHODS:After a policy chang...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e318057f319
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:A historic cohort analysis was performed to assess the colposcopic and histologic correlates of atypical squamous cells of undetermined significance (ASCUS) Pap smears in pregnant and nonpregnant women. MATERIALS AND METHODS:A chart review of all gynecologic and obstetric patients seen in the outpatient clin...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/00128360-200204000-00008
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Vulvar fissures are a common cause of vulvar pain and discomfort. The differential diagnosis of the underlying process is broad, and some cases remain undiagnosed. Mycosis fungoides, the dominant component of cutaneous T-cell lymphoma, rarely present as fissures. We report a case of a chronic vulvar fissure ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e31819d09ad
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:To determine whether Hybrid Capture 2 High-Risk HPV DNA Test (HC2) can be used as a test of cure in women treated for cervical intraepithelial neoplasia grade 2 or worse (CIN 2+) and allow discharge from colposcopy follow-up with a return to a cytology-based screening program for HC2-negative women. MATERIA...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000349
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:The Home Study Course is intended for the practicing colposcopist or practitioner who is seeking to develop or enhance his/her colposcopic skills. The goal of the course is to present colposcopic cases that are unusual or instructive in terms of appearance, presentation, or management, or that demonstrate new...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/lgt.0b013e3180380fd3
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:To compare the collection of vaginal exudates with and without the use of a speculum to diagnose vaginal infections. MATERIAL AND METHODS:We examined 45 patients with vaginal discharge. Two vaginal swabs were taken, one with and the other without a speculum. Both were examined by wet mount microscopy to detect...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/01.lgt.0000179859.29456.ba
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:The current study tested the hypothesis that collagen content in the pregnant cervix decreases with labor, using morphologically preserved specimens, avoiding limitations of earlier studies. Collagen abundance remote from pregnancy was also evaluated. MATERIALS AND METHODS:Histologic sections of postpartum c...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e31822bb004
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:Metronidazole vaginal gel (MVG) 0.75% is a US Food and Drug Administration-approved, 5-day treatment for bacterial vaginosis (BV). This study tested the hypothesis that a shorter treatment course at a higher dose (MVG 1.3%) would yield similar efficacy to 5 days of MVG 0.75%. MATERIALS AND METHODS:This phase...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/LGT.0000000000000062
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to determine rates of cervical intraepithelial neoplasia (CIN) 2 or greater in high-risk, racially diverse, young women with low-grade cytology. MATERIALS AND METHODS:After institutional review board approval, a cross-sectional study of 21- to 24-year-old women with low-grade cytolog...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000381
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:To compare the colposcopic adequacy, colposcopic impressions, histologic sampling intent, biopsy site location, procedural complications, and difficulty of colposcopic examinations using optical and video colposcopes. MATERIALS AND METHODS:Women and men presenting consecutively for colposcopy were examined i...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVE:In this study, we investigated whether physical inactivity was associated with risk of cervical cancer in women treated at an American cancer hospital. METHODS:This case-control study included 128 patients with cervical cancer and 512 controls matched on age. Controls were women suspected of having but not u...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000210
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to quantify personal stories about cervical cancer and to determine the proportion and sentiment (positive vs negative) of messages ("tweets") that discussed cervical cancer prevention strategies on Twitter. METHODS:This study was a cross-sectional Twitter review of English...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000363
更新日期:2018-01-01 00:00:00
abstract::Rituximab is being used increasingly for the treatment of B-cell malignancies and nonmalignant conditions. Pyoderma gangrenosum is a rare neutrophilic dermatosis, which can be either idiopathic or associated with underlying systemic inflammatory conditions. We present a series of 4 patients who presented with ulcerati...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000043
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:To report the outcome of patients diagnosed with cervical intraepithelial neoplasia 2, 3 (CIN 2, 3) during pregnancy, who were treated by large loop excision of the transformation zone (LLETZ) in the first trimester or were followed up conservatively and treated after delivery. METHODS:Patients diagnosed wi...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e318299c0af
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to compare the effectiveness of mindfulness-based group cognitive behavior therapy (M-gCBT) versus education support group therapy for the pain and distress associated with provoked localized vulvodynia. MATERIALS AND METHODS:Participants were randomized to M-gCBT or education suppor...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,随机对照试验
doi:10.1097/LGT.0000000000000456
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the feasibility and efficiency of direct visual inspection after Lugol iodine painting in detecting cervical premalignant and malignant lesions. MATERIALS AND METHODS:This study included 1,012 women recruited from gynecology outpatient clinic screened for premalignant or malignant lesions of the ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e31815f527c
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVE:This study aimed to compare digital camera assessment of the reproductive tract (DART) to colposcopy for the evaluation of abnormal Pap smears. MATERIALS AND METHODS:Participants included 207 women with abnormal Pap smears. Colposcopy and DART were performed on each patient by separate examiners with the goa...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e3181a02058
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to evaluate the validity of anal cytology against high-resolution anoscopy in the detection of anal high-grade squamous intraepithelial lesions (HSILs) among women in a clinical setting in Puerto Rico, alone and in combination with high-risk human papillomavirus (HR-HPV) typing. MATE...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000497
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:The Home Study Course is intended for the practicing colposcopist or practitioner who is seeking to develop or enhance his or her colposcopic skills. The goal of the course is to present colposcopic cases that are unusual or instructive in terms of appearance, presentation, or management, or that demonstrate ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/00128360-200407000-00013
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:Visual assessment of digitized cervigrams through the Internet needs to be optimized. The National Cancer Institute and National Library of Medicine are involved in a large effort to improve colposcopic assessment and, in preparation, are conducting methodologic research. MATERIALS AND METHODS:We selected 50...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/01.lgt.0000192696.93172.ae
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to describe temporal trends in screening and outcomes for women, after changes in guidelines in Alberta, Canada, that raised starting age to 21 years, then to 25 years of age, and reduced frequency to 3 yearly. MATERIALS AND METHODS:Calgary Laboratory Information System data were use...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000574
更新日期:2021-01-01 00:00:00
abstract:UNLABELLED:▪ OBJECTIVE:: The Home Study Course is intended for the practicing colposcopist or practitioner who is seeking to develop or enhance his or her colposcopic skills. The goal of the course is to present colposcopic cases that are unusual or instructive in terms of appearance, presentation, or management, or t...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVE:To determine the utility of random biopsy and endocervical curettage (ECC) during colposcopy among women who ultimately underwent cervical excisional biopsy. MATERIALS AND METHODS:In a retrospective observational study, the charts were reviewed of every patient who underwent cervical excisional procedure per...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e3182a5296e
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:The study aimed to identify sociodemographic and disease-specific factors associated with follow-up in an inner-city multiethnic colposcopy clinic. MATERIALS AND METHODS:All charts of patients referred to colposcopy clinic for abnormal cervical cytology and/or high-risk human papillomavirus infections to the...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e318249640f
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:Bacterial vaginosis (BV) is a common cause of genital discomfort in women in reproductive ages, which causes many complications. Bacterial vaginosis is usually treated by metronidazole and clindamycin. However, this protocol does not prevent its recurrence, which is a main complaint of the patients. The numbe...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,评审
doi:10.1097/LGT.0b013e31829156ec
更新日期:2014-01-01 00:00:00
abstract::OBJECTIVES.: This study evaluates the long-term clinical success of Durasphere (Carbon Metal Technologies, St. Paul, MN) compared with Contigen (C. R. Bard, Covington, GA) in the treatment of stress urinary incontinence caused by intrinsic sphincter deficiency (ISD). METHODS.: Fifty-two women diagnosed with stress uri...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/00128360-200210000-00009
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:This study aimed to report 2 cases of squamous cell carcinoma (SCC) of the vulva, arising from unusual subepithelial locations. MATERIALS AND METHODS:The first case was of an 85-year-old woman with a 65-year history of a mass in the left labium majus. The second case was of a 54-year-old woman who presented ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e31827a8c95
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:This study aimed to conduct a representative survey of human papillomavirus (HPV) prevalence and its genotype distribution in invasive anal cancer specimens in the United States. MATERIALS AND METHODS:Population-based archival anal cancer specimens were identified from Florida, Kentucky, Louisiana, and Michi...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e31827ed372
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:: This study aimed to investigate correlations between a panel of biomarkers/tumor markers and high-risk (HR) human papillomavirus (HPV)-positive versus HR-HPV-negative cervical lesions. MATERIALS AND METHODS:: The study included 188 women who consecutively attended a colposcopy clinic because of PAP smears ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e318215170c
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:To compare rates of cervical intraepithelial neoplasia grade 3 or greater (CIN3+) between women aged 21 to 24 and women aged 25 or older undergoing a see-and-treat strategy for high-grade squamous intraepithelial lesion (HSIL) cytology. METHODS:In this retrospective cohort study, women treated with a see-and...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000229
更新日期:2016-07-01 00:00:00