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Isolation and characterization of metallothionein dimers.

Abstract：

:The dimeric forms of metallothionein were isolated from livers of rabbits which accumulated cadmium in large quantities. The dimers were separated into three isoproteins, both on a DEAE Sephadex A-25 column and on a gel permeation column. Reduction of each dimer with mercaptoethanol yielded monomeric metallothionein-I, an equivalent mixture of metallothionein-I and -II, and metallothionein-II. The three isoproteins were identified as a dimer of metallothionein-I, a dimer of metallothionein-I and -II, and a dimer of metallothionein-II, respectively.

journal_name

Biochem Pharmacol

journal_title

Biochemical pharmacology

authors

Suzuki KT,Yamamura M

doi

10.1016/0006-2952(80)90540-7

subject

Has Abstract

pub_date

1980-03-01 00:00:00

pages

689-92

issue

5

eissn

0006-2952

issn

1873-2968

pii

0006-2952(80)90540-7

journal_volume

29

pub_type

杂志文章

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