当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > Randomized comparative trial of indomethacin and ritodrine for the long-term treatment of preterm labor.

Randomized comparative trial of indomethacin and ritodrine for the long-term treatment of preterm labor.

Abstract：

:A randomized prospective trial was performed to compare the efficacy and safety of ritodrine and indomethacin in the long-term treatment of preterm labor. Forty patients with intact membranes in preterm labor at 23 to 34 weeks' gestation were randomized to receive either intravenous ritodrine or oral indomethacin as the first-line tocolytic agent. Successful intravenous ritodrine therapy was followed by oral terbutaline therapy, and indomethacin-treated patients continued to receive oral indomethacin. Treatment failures were defined as progressive preterm labor or patient intolerance, and these patients were treated with intravenous magnesium sulfate. Ritodrine and indomethacin were equally successful in delaying preterm birth as defined by interval to delivery, gestational age at delivery, delivery delayed greater than 7 days, attainment of 35 weeks of gestation, percentage of patients who required magnesium sulfate therapy, percentage of patients who were readmitted with premature rupture of membranes, absence of recurrent preterm labor, and infant birth weight. More than 80% of mothers who received ritodrine voiced complaints of beta-sympathomimetic side effects, and one patient discontinued treatment as the result of intolerance. There were minimal patient complaints with indomethacin use. No statistically significant differences were noted in neonatal outcome as defined by Apgar scores, umbilical cord pH, intensive care days, ventilator days, or neonatal deaths. However, three cases of primary pulmonary hypertension were observed in the indomethacin group. We had not previously observed this problem with short-term (24 to 48 hours) indomethacin therapy.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Besinger RE,Niebyl JR,Keyes WG,Johnson TR

doi

10.1016/0002-9378(91)90569-d

subject

Has Abstract

pub_date

1991-04-01 00:00:00

pages

981-6; discussion 986-8

issue

4

eissn

0002-9378

issn

1097-6868

pii

0002-9378(91)90569-D

journal_volume

164

pub_type

临床试验,杂志文章,随机对照试验

相关文献

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY文献大全
  • Comparison of results of microbiologic and radioisotopic assays for serum vitamin B12 during pregnancy.

    abstract：:The serum vitamin B12 level falls progressively during pregnancy, when measured either by microbiologic assay or by a radioisotope dilution technique. The concentration of the vitamin assayed by radioisotope dilution was consistently higher than the value obtained by microbiologic assay. This discrepancy was greatest ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(75)90609-2

    authors： Green R,Colman N,Metz J

    更新日期：1975-05-01 00:00:00

  • Ultrasound fetal femur length in relation to intrauterine growth retardation. Part II.

    abstract：:With the establishment of a normal range of values for the growth of the ultrasound fetal femur length, a new approach for the study of growth-retarded fetuses is suggested. Ultrasound femur length was measured on a group of "high-risk" pregnancies, and its ability to differentiate the symmetrically small from the asy...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(82)90390-8

    authors： O'Brien GD,Queenan JT

    更新日期：1982-09-01 00:00:00

  • Effect of oral contraceptives on rhythmic urinary metal excretion.

    abstract：:Thirteen women, six of whom were using oral contraceptive agents, between the ages of 23 and 34 years, free from illness, and without a previous clinical history of menstrual abnormality, were studied with chronobiological methods for circadian (about 24 hour) patterns of metal and creatinine excretinine excretion. Ci...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(16)33342-7

    authors： Weinmann S,Dawson EB,Smolensky MH,Weisberg RF,Lane B,Bryan S

    更新日期：1976-04-01 00:00:00

  • Serum levels of the ovarian cancer biomarker HE4 are decreased in pregnancy and increase with age.

    abstract：OBJECTIVE:The purpose of this study was to establish normal ranges for human epididymis protein 4 (HE4) serum levels in healthy women. STUDY DESIGN:HE4 levels were measured in healthy women and analyzed by age, menopausal status, and pregnancy status. Upper 95th percentiles were determined for normal ranges. RESULTS:...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.ajog.2011.12.028

    authors： Moore RG,Miller MC,Eklund EE,Lu KH,Bast RC Jr,Lambert-Messerlian G

    更新日期：2012-04-01 00:00:00

  • Maternal serum screening for fetal Down syndrome in the United States: a 1992 survey.

    abstract：OBJECTIVE:Our purpose was to determine the status of screening for fetal Down syndrome in the United States in 1992. STUDY DESIGN:Information was sought from laboratories participating in two proficiency testing programs. RESULTS:The 301 responding laboratories (98%) annually provided services to 2,113,000 pregnant w...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(93)90436-m

    authors： Palomaki GE,Knight GJ,McCarthy J,Haddow JE,Eckfeldt JH

    更新日期：1993-12-01 00:00:00

  • Gestational age limit of twelve weeks for abortion by curettage.

    abstract：:A brief review of the evidence for and against the 12-week gestational age limit for abortion by curettage is reported. Existing data suggest that second trimester evacuation abortion is associated with higher morbidity and mortality rates than first trimester suction curettage, but with lower rates than second trime...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(78)90925-0

    authors： Grimes DA,Cates W Jr

    更新日期：1978-09-15 00:00:00

  • Enlarged cisterna magna in trisomy 18: prenatal ultrasonographic diagnosis.

    abstract：:Ultrasonographic visualization of an enlarged cisterna magna was the initial clue that led to the prenatal diagnosis of trisomy 18 in five patients. Prenatal diagnosis of trisomy 18, a lethal defect, is important for proper patient counseling and management. ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(89)90238-x

    authors： Thurmond AS,Nelson DW,Lowensohn RI,Young WP,Davis L

    更新日期：1989-07-01 00:00:00

  • Concept mapping: a tool to bridge the disciplinary divide.

    abstract：:The American College of Women's Health Physicians has been exploring an on-line educational tool-concept mapping-to facilitate the development of an interdisciplinary and woman-centered women's health curriculum, and to implement The Women's Health Care Competencies for Medical Students. By using an on-line concept ma...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2002.127360

    authors： Hoffman E,Trott J,Neely KP

    更新日期：2002-09-01 00:00:00

  • Low-dose aspirin in the prevention of preeclampsia and fetal growth retardation: rationale, mechanisms, and clinical trials.

    abstract：:Preeclampsia is characterized by a functional imbalance between vascular prostacyclin and thromboxane A2 production. On the basis of the hypothesis that preeclampsia is at least partially caused by an increase in thromboxane A2, some studies attempted to correct this pathologic condition by pharmacologic manipulation ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/s0002-9378(12)90917-5

    authors： Dekker GA,Sibai BM

    更新日期：1993-01-01 00:00:00

  • Effects of pregnancy and fasting on muscle glucose utilization in the rabbit.

    abstract：:The effects of fasting on maternal glucose metabolism were investigated in nonpregnant and 29-day pregnant conscious rabbits. Pregnancy decreased the glucose metabolic index by 60% in maternal red postural muscles. Fasting induced similar modifications in nonpregnant rabbits and exaggerated the changes observed in fed...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(88)90257-8

    authors： Hauguel S,Leturque A,Gilbert M,Girard J

    更新日期：1988-05-01 00:00:00

  • An abnormal umbilical artery waveform: a strong and independent predictor of adverse perinatal outcome in patients with preeclampsia.

    abstract：OBJECTIVE:An abnormal umbilical artery Doppler waveform is a risk factor for adverse perinatal outcome. However, it has not been established whether this is related to the earlier gestational age at delivery of fetuses with abnormal Doppler findings or whether Doppler findings are an independent predictor of perinatal ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(94)90087-6

    authors： Yoon BH,Lee CM,Kim SW

    更新日期：1994-09-01 00:00:00

  • The use of color Doppler imaging for prenatal diagnosis of umbilical cord anomalies: report of three cases.

    abstract：:Color Doppler imaging could easily and rapidly detect the absence of an umbilical artery, despite the presence of oligohydramnios in one case and multiple cord loops involving a normal cord in the other case. In the third case, which on gray-scale imaging appeared as an indeterminate cystic structure of the cord, colo...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(89)90663-7

    authors： Jauniaux E,Campbell S,Vyas S

    更新日期：1989-11-01 00:00:00

  • Endometritis following cesarean section. A controlled study of the increased duration of hospital stay and direct cost of hospitalization.

    abstract：:The increased hospital stay and direct costs of hospitalization as a result of postcesarean section endometritis were evaluated in a case-matched and controlled study (N = 20 in each group). Endometritis increased postcesarean section hospital stay by 3 days and increased hospital cost by $850. Fifteen to 20% of women...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章

    doi：

    authors： Donowitz LG,Wenzel RP

    更新日期：1980-06-15 00:00:00

  • Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 2 or 3 among women with cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy.

    abstract：OBJECTIVE:The purpose of this study was to determine the risk of cumulative cervical intraepithelial neoplasia (CIN) grade 2 or 3 according to initial colposcopy and directed biopsy results among women with low-grade squamous intraepithelial lesions (LSIL) or human papillomavirus (HPV) DNA positive atypical squamous ce...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2003.461

    authors： Cox JT,Schiffman M,Solomon D,ASCUS-LSIL Triage Study (ALTS) Group.

    更新日期：2003-06-01 00:00:00

  • Androgen insensitivity syndrome: gonadal androgen receptor activity.

    abstract：:To determine whether abnormalities of the androgen receptor previously observed in skin fibroblasts from patients with androgen insensitivity syndrome also occur in the gonads of affected individuals, androgen receptor activity in the gonads of a patient with testicular feminization syndrome was investigated. Using co...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(84)90434-4

    authors： Coulam CB,Graham ML 2nd,Spelsberg TC

    更新日期：1984-11-01 00:00:00

  • Uterine venous, peripheral venous, and radial arterial levels of prostaglandins E and F in women with pregnancy-induced hypertension.

    abstract：:Patients with pregnancy-induced hypertension have higher prostaglandin (PG) F concentrations in radial arterial blood (0.39 +/- 0.03 ng/ml) than control subjects (0.24 +/- 0.03 ng/ml) and higher (PGE plus PGF) concentrations in uterine venous blood obtained at the time of cesarean section (1.62 +/- 0.18 versus 1.03 +/...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(83)90333-2

    authors： Valenzuela G,Harper MJ,Hayashi RH

    更新日期：1983-01-01 00:00:00

  • Maternal disability and risk for pregnancy, delivery, and postpartum complications: a systematic review and meta-analysis.

    abstract：BACKGROUND:Women with disabilities are increasingly becoming pregnant, and growing evidence suggests maternal disability may be associated with increased risk for perinatal complications. OBJECTIVE:A systematic review and meta-analysis were undertaken to examine the association between maternal disabilities and risk f...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.ajog.2019.07.015

    authors： Tarasoff LA,Ravindran S,Malik H,Salaeva D,Brown HK

    更新日期：2020-01-01 00:00:00

  • Incidence of fever in labor and risk of neonatal sepsis.

    abstract：BACKGROUND:The current recommendation regarding the management of a term newborn delivered of a mother with an intrapartum fever or a diagnosis of clinical chorioamnionitis is that the neonate should have baseline laboratory work drawn along with blood cultures and be universally treated with antibiotics until culture ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2017.02.022

    authors： Towers CV,Yates A,Zite N,Smith C,Chernicky L,Howard B

    更新日期：2017-06-01 00:00:00

  • Iatrogenic respiratory distress syndrome. An analysis of obstetric events preceding delivery of infants who develop respiratory distress syndrome.

    abstract：:The obstetric events leading to the birth of infants who developed respiratory distress syndrome (RDS) were evaluated. In a retrospective study of 100 consecutive cases it was determined that untimely or unwarranted physician intervention in the pregnancy was responsible for 15 per cent of cases and possibly responsib...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：

    authors： Goldenberg RL,Nelson K

    更新日期：1975-11-15 00:00:00

  • Symptomatic pelvic organ prolapse in middle-aged women: a national matched cohort study on the influence of childbirth.

    abstract：BACKGROUND:The relative impact of age, pregnancy, and vaginal delivery on symptomatic pelvic organ prolapse is still an unresolved issue that involves the controversial question about the protective effect of cesarean section. OBJECTIVE:The purpose of this study was to compare the age-related prevalence of symptomatic...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2019.10.007

    authors： Åkervall S,Al-Mukhtar Othman J,Molin M,Gyhagen M

    更新日期：2020-04-01 00:00:00

  • High plasma cellular fibronectin levels correlate with biochemical and clinical features of preeclampsia but cannot be attributed to hypertension alone.

    abstract：:Current concepts of the pathogenesis of preeclampsia involve the generalized dysfunction of maternal vascular endothelial cells. We measured the endothelial isoform of fibronectin as a marker of endothelial cell injury throughout pregnancy in a prospective, case-control study. Nineteen women met strict criteria for th...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(91)90435-t

    authors： Taylor RN,Crombleholme WR,Friedman SA,Jones LA,Casal DC,Roberts JM

    更新日期：1991-10-01 00:00:00

  • Conservative treatment of ectopic pregnancy with methotrexate.

    abstract：:Six subjects with distal ampullary ectopic pregnancies were treated with four doses of intravenous methotrexate (1.0 mg/kg) followed by four doses of leucovorin (0.1 mg/kg, intramuscularly). The diagnosis was established in all cases by laparoscopy following sonography and radioimmunoassay for serum beta subunit of hu...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(86)90716-7

    authors： Ory SJ,Villanueva AL,Sand PK,Tamura RK

    更新日期：1986-06-01 00:00:00

  • Risks and usefulness of sonohysterography in patients with endometrial carcinoma.

    abstract：OBJECTIVE:The purposes of this study were to assess the risk of malignant cell dissemination into the peritoneal cavity through the fallopian tubes in patients with endometrial carcinoma undergoing sonohysterography and to evaluate the accuracy of sonohysterography in the estimation of myometrial invasion by the tumor ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2005.08.036

    authors： Dessole S,Rubattu G,Farina M,Capobianco G,Cherchi PL,Tanda F,Gallo O,Ambrosini G

    更新日期：2006-02-01 00:00:00

  • Intrauterine administration of methyl cyanoacrylate as an outpatient method of permanent female sterilization.

    abstract：:Results are presented of multicenter studies on the intrauterine delivery of 0.6 ml methyl cyanoacrylate with the FEMCEPT device (BioNexus Inc., Raleigh, North Carolina) for the purpose of causing permanent obstruction of the fallopian tubes. The studies included 1279 women and were conducted under several different p...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(87)90373-5

    authors： Richart RM,Neuwirth RS,Goldsmith A,Edelman DA

    更新日期：1987-04-01 00:00:00

  • National patterns of care and fertility outcomes for reproductive-aged women with endometrial cancer or atypical hyperplasia.

    abstract：BACKGROUND:Although it is uncommon, the incidence of endometrial cancer and atypical hyperplasia among reproductive-aged women is increasing. The fertility outcomes in this population are not well described. OBJECTIVE:We aim to describe the patterns of care and fertility outcomes of reproductive-aged women with endome...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2019.05.029

    authors： Harrison RF,He W,Fu S,Zhao H,Sun CC,Suidan RS,Woodard TL,Rauh-Hain JA,Westin SN,Giordano SH,Meyer LA

    更新日期：2019-11-01 00:00:00

  • Laparoscopic incidental appendectomy during laparoscopic surgery for ovarian endometrioma.

    abstract：OBJECTIVE:We sought to investigate the safety and efficacy of laparoscopic incidental appendectomy during laparoscopic surgery for endometrioma. STUDY DESIGN:We conducted a retrospective study of 356 patients undergoing laparoscopic surgery for endometrioma with appendectomy (appendectomy group, n = 172) or not (nonap...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2010.08.042

    authors： Lee JH,Choi JS,Jeon SW,Son CE,Bae JW,Hong JH,Lee KW,Lee YS

    更新日期：2011-01-01 00:00:00

  • Validating a clinical measure of levator hiatus size.

    abstract：OBJECTIVE:We evaluate the interrater reliability of levator hiatus (LH) size and correlate size to other measures of muscle function. STUDY DESIGN:Participants were examined independently by 2 examiners. During maximal contraction of the levator ani, the muscle was assessed by using Brink's scale. The LH was measured ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2006.08.028

    authors： Boyles SH,Edwards SR,Gregory WT,Denman MA,Clark AL

    更新日期：2007-02-01 00:00:00

  • Relationship of fetal growth to duration of heat stress in an ovine model of placental insufficiency.

    abstract：OBJECTIVE:Intrauterine growth restriction in an ovine model occurs after exposure to environmental heat stress for 80 days beginning at 35 days' gestation. Our objective was to determine whether intrauterine growth restriction is reversible on removal of the heat stress after only 55 days of exposure; that is, does a b...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(99)70629-0

    authors： Galan HL,Hussey MJ,Barbera A,Ferrazzi E,Chung M,Hobbins JC,Battaglia FC

    更新日期：1999-05-01 00:00:00

  • Outcomes of newborns with gastroschisis: the effects of mode of delivery, site of delivery, and interval from birth to surgery.

    abstract：OBJECTIVE:Our purpose was to determine the impact of delivery site, delivery mode, and delivery-to-surgery interval on outcomes for neonates diagnosed with gastroschisis. STUDY DESIGN:Data were obtained retrospectively by chart review on 56 newborns diagnosed with gastroschisis. Outcome measures examined included prim...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(96)70655-5

    authors： Quirk JG Jr,Fortney J,Collins HB 2nd,West J,Hassad SJ,Wagner C

    更新日期：1996-04-01 00:00:00

  • Clinically accurate fetal ECG parameters acquired from maternal abdominal sensors.

    abstract：OBJECTIVE:We sought to evaluate the accuracy of a novel system for measuring fetal heart rate (FHR) and ST-segment changes using noninvasive electrodes on the maternal abdomen. STUDY DESIGN:Fetal electrocardiograms were recorded using abdominal sensors from 32 term laboring women who had a fetal scalp electrode (FSE) ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2011.02.066

    authors： Clifford G,Sameni R,Ward J,Robinson J,Wolfberg AJ

    更新日期：2011-07-01 00:00:00