[Clinical trial with a new anti-epileptic: barbexaclone].

Abstract:

:A new anti-epileptic agent (barbexaclone) was tried in 48 patients suffering from epilepsy and presenting a total of 67 types of crises. All the patients were considered "bad cases" because either by the intensity of the epileptic manifestations or by their refractoriness to the usual medications. The results, similar to others already published, could be considered as good for grand mal epilepsy both for those convulsions occurring during either the sleeping or waking hours and suggest further observations in focal crises. Though not considered as a first line medication in petit mal seizuras the drug gave excellent results when used as an adjuvant in the supression of absences and the annulation of convulsant effects of some drugs used in petit mal. No toxic reactions were noted, and the side effects, which were never very intense, tended to disappear in the majority of cases with continued use of the drug.

journal_name

Arq Neuropsiquiatr

authors

Bragatti JH,Caleffi GH,Prenna FJ

doi

10.1590/s0004-282x1977000300012

subject

Has Abstract

pub_date

1977-09-01 00:00:00

pages

277-81

issue

3

eissn

0004-282X

issn

1678-4227

journal_volume

35

pub_type

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