Abstract:
:Anidulafungin is an antifungal drug belonging to the echinocandin class with a potent in vitro fungicidal activity against a wide range of Candida species, including C. glabrata and C. krusei. Anidulafungin is also active in vitro against moulds belonging to the genus Aspergillus and some dematiaceous genera. Furthermore, anidulafungin demonstrates in vitro activity against Candida spp. growing as biofilms. Resistance to anidulafungin remains very rare based on recent epidemiological data. Paradoxical or trailing effects should be considered in echinocandin susceptibility testing. The in vitro activity profile of anidulafungin makes it a useful addition to the Italian antifungal armamentarium.
journal_name
Drugsjournal_title
Drugsauthors
Morace G,Borghi E,Iatta R,Montagna MTdoi
10.2165/11315560-000000000-00000subject
Has Abstractpub_date
2009-01-01 00:00:00pages
91-4eissn
0012-6667issn
1179-1950pii
14journal_volume
69 Suppl 1pub_type
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