Abstract:
:IS91 is the prototype element of a family of bacterial insertion sequences that transpose by a rolling-circle mechanism. Although previously considered a rarity among IS elements, many new examples have been identified by sequence analysis of bacterial genomes. In this work we provide a summary of occurrences of IS91-like sequences in the GenBank database, characterise the genetic organisation of adjacent sequences, and analyse IS91 ecological significance under the light of current transposition mechanisms. Interestingly, IS91 family elements were usually found adjacent to pathogenicity- and virulence-related genes. Thus, this might constitute the niche for IS91 and IS91 family elements to play an important role in the dissemination and evolution of virulence and pathogenicity types of genes.
journal_name
FEMS Microbiol Ecoljournal_title
FEMS microbiology ecologyauthors
Garcillán-Barcia MP,de la Cruz Fdoi
10.1111/j.1574-6941.2002.tb01020.xsubject
Has Abstractpub_date
2002-11-01 00:00:00pages
303-13issue
2eissn
0168-6496issn
1574-6941pii
FEM303journal_volume
42pub_type
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