当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > Antenatal glucocorticoid therapy increases glucose delivery to cerebral circulations during acute hypoxemia in fetal sheep during late gestation.

Antenatal glucocorticoid therapy increases glucose delivery to cerebral circulations during acute hypoxemia in fetal sheep during late gestation.

Abstract：

OBJECTIVE:To determine the effects of 2 maternal injections with dexamethasone on the calculated oxygen and glucose deliveries to fetal cerebral and peripheral circulations during acute hypoxemia in sheep. STUDY DESIGN:Beginning at 124 days, ewes received 2 intramuscular injections of either dexamethasone (2 x 12 mg, n = 10) or saline solution (2 x 2 mL, n = 12) 24 hours apart. Hypoxemia (1 hour) was induced 32 hours after the first injection (H1) and 3 days after the second (H2). RESULTS:In saline solution-treated fetuses, glucose delivery was unchanged or increased in femoral and carotid circulations, respectively, during H1 and H2. In dexamethasone-treated fetuses, the increase in glucose delivery to the head tended to be greater during H1 and was significantly enhanced in dexamethasone- vs saline solution-treated fetuses during H2. CONCLUSION:Two maternal injections with dexamethasone significantly enhanced glucose delivery to the head during acute hypoxemia in the ovine fetus.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Jellyman JK,Gardner DS,McGarrigle HH,Fowden AL,Giussani DA

doi

10.1016/j.ajog.2009.01.012

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

82.e1-8

issue

1

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(09)00018-0

journal_volume

201

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY文献大全
  • Prepubertal labial adhesions: evaluation of a referral population.

    abstract：OBJECTIVE:The purpose of this study was to assess patient demographics, clinical presentation, response to previous treatment, and current evaluation of prepubertal girls referred for gynecologic care of labial agglutination. STUDY DESIGN:A retrospective chart review of all prepubertal female patients with labial aggl...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2002.126201

    authors： Bacon JL

    更新日期：2002-08-01 00:00:00

  • Comparison of adnexal torsion between pregnant and nonpregnant women.

    abstract：OBJECTIVE:The purpose of this study was to compare clinical manifestations, treatment, and pregnancy outcome of adnexal torsion in pregnant and nonpregnant women. STUDY DESIGN:We conducted a retrospective case-control study in the Departments of Gynecology at 2 tertiary centers between 1999-2008. Forty-one pregnant an...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2009.11.028

    authors： Hasson J,Tsafrir Z,Azem F,Bar-On S,Almog B,Mashiach R,Seidman D,Lessing JB,Grisaru D

    更新日期：2010-06-01 00:00:00

  • National patterns of care and fertility outcomes for reproductive-aged women with endometrial cancer or atypical hyperplasia.

    abstract：BACKGROUND:Although it is uncommon, the incidence of endometrial cancer and atypical hyperplasia among reproductive-aged women is increasing. The fertility outcomes in this population are not well described. OBJECTIVE:We aim to describe the patterns of care and fertility outcomes of reproductive-aged women with endome...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2019.05.029

    authors： Harrison RF,He W,Fu S,Zhao H,Sun CC,Suidan RS,Woodard TL,Rauh-Hain JA,Westin SN,Giordano SH,Meyer LA

    更新日期：2019-11-01 00:00:00

  • The fetoplacental pressor effects of low-dose acetylsalicylic acid and angiotensin II in the ex vivo cotyledon model.

    abstract：OBJECTIVE:Our purpose was to investigate perfusion pressure changes ex vivo induced by angiotensin II on fetoplacental vasculature pretreated with low-dose acetylsalicylic acid. STUDY DESIGN:Two cotyledons from each of 12 placentas were perfused. The intervillous space of one cotyledon was infused with acetylsalicylic...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(97)70021-8

    authors： Napolitano PG,Hoeldtke NJ,Moore KH,Calhoun BC,Christensen ED,Markenson GR,Hume RF Jr

    更新日期：1997-11-01 00:00:00

  • Analysis of 500 obstetric and gynecologic malpractice claims: causes and prevention.

    abstract：:Five hundred obstetric and gynecologic malpractice litigation claims were analyzed to determine the incidence of claims that could not be defended because of breach of standards of care, problems with documentation, or both. Of the 500 claims, 294 were obstetric and 206 were gynecologic. Of the obstetric claims, 79 (2...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(91)90082-3

    authors： Ward CJ

    更新日期：1991-08-01 00:00:00

  • Failure of ibuprofen in treatment of herpes genitalis.

    abstract：:Motrin (ibuprofen), a potent inhibitor of prostaglandin synthetase, was tested in women and men for treatment of recurrences of genital herpes. In a double-blind trial, no statistically significant differences were observed between treated and placebo groups in any of the measured parameters. ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章

    doi：10.1016/0002-9378(86)90842-2

    authors： Milch PO,Monheit AG,Rochelson BL,Metz G,Baker DA

    更新日期：1986-08-01 00:00:00

  • Impact of menopause on collagen subtypes in the arcus tendineous fasciae pelvis.

    abstract：OBJECTIVE:The arcus tendineous fasciae pelvis (ATFP) provides support to the anterior vagina. The objective of this study was to determine the impact of menopause on the structural components of the ATFP. STUDY DESIGN:Biopsy specimens of the ATFP were obtained from 10 premenopausal, 5 postmenopausal, and 12 postmenopa...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2003.08.040

    authors： Moalli PA,Talarico LC,Sung VW,Klingensmith WL,Shand SH,Meyn LA,Watkins SC

    更新日期：2004-03-01 00:00:00

  • The maternal-fetal transfer of lamivudine in the ex vivo human placenta.

    abstract：OBJECTIVE:Our purpose was to measure the transfer of lamivudine ([-]-2'-deoxy-3'-thiacytidine) across the human placenta both alone and in the presence of zidovudine. STUDY DESIGN:Nine placentas from term, elective cesarean deliveries were analyzed with use of the ex vivo single cotyledon perfusion system. Antipyrine ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(97)70487-3

    authors： Bloom SL,Dias KM,Bawdon RE,Gilstrap LC 3rd

    更新日期：1997-02-01 00:00:00

  • Benign gynecologic conditions among participants in the Breast Cancer Prevention Trial.

    abstract：OBJECTIVE:This study was undertaken to report on the benign gynecologic conditions occurring among women with an intact uterus at enrollment in the Breast Cancer Prevention Trial of the National Surgical Adjuvant Breast and Bowel Project. STUDY DESIGN:The incidence rates of several benign gynecologic conditions were d...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.ajog.2004.12.083

    authors： Chalas E,Costantino JP,Wickerham DL,Wolmark N,Lewis GC,Bergman C,Runowicz CD

    更新日期：2005-04-01 00:00:00

  • Antenatal corticosteroid administration: understanding its use as an obstetric quality metric.

    abstract：OBJECTIVE:In 1994, the National Institutes of Health recommended a full course of antenatal corticosteroids (ACS) to women who were at risk of delivery at 24-32 weeks of gestation. In 2010, the Joint Commission on Accreditation of Healthcare Organization incorporated ACS administration rates as a perinatal core quality...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2013.09.024

    authors： Chandrasekaran S,Srinivas SK

    更新日期：2014-02-01 00:00:00

  • Suburethral sling using the transobturator approach: a quality-of-life analysis.

    abstract：OBJECTIVE:The objective of the study was to determine the degree of benefit of a transobturator midurethral polypropylene sling in patients with stress urinary incontinence through a quality-of-life instrument and outcome analysis. STUDY DESIGN:Forty-seven patients completed the validated Individual Incontinence Impac...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2005.07.036

    authors： Lukban JC

    更新日期：2005-12-01 00:00:00

  • The effect of the oxytocin antagonist atosiban on preterm uterine activity in the human.

    abstract：OBJECTIVE:The purpose of this study was to test the hypothesis that infusion of the oxytocin antagonist atosiban results in decreased preterm uterine activity in the human. STUDY DESIGN:A randomized, double-blind, placebo-controlled trial was performed. One hundred twenty women from 20 to 36 weeks' gestation with a co...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/s0002-9378(94)70214-4

    authors： Goodwin TM,Paul R,Silver H,Spellacy W,Parsons M,Chez R,Hayashi R,Valenzuela G,Creasy GW,Merriman R

    更新日期：1994-02-01 00:00:00

  • Umbilical artery Doppler velocimetry: clinical utility in high-risk pregnancies.

    abstract：:An abnormal result of an umbilical artery Doppler study reflects the presence of placental vascular pathologic mechanisms and identifies pregnancies at increased risk for perinatal mortality. Recent reviews of the clinical utility of umbilical artery Doppler study have concluded that it should not be routinely used as...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/s0002-9378(96)70365-4

    authors： Divon MY

    更新日期：1996-01-01 00:00:00

  • Comparison of protein S functional and antigenic assays in normal pregnancy.

    abstract：OBJECTIVE:Our purpose was to determine the effect of pregnancy on the protein S functional assay (clot based), which is used to screen for all subtypes of protein S deficiency states, and to compare its behavior in pregnancy with antigenic assays. STUDY DESIGN:This was a cross-sectional study of 37 normal pregnant wom...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1053/ob.1996.v175.a73866

    authors： Lefkowitz JB,Clarke SH,Barbour LA

    更新日期：1996-09-01 00:00:00

  • Intravascular transfusion in utero: the percutaneous approach.

    abstract：:A severely Rh-isoimmunized pregnancy is described in which an intrauterine transfusion of blood was given by the intravascular route directly into an umbilical vessel. Fetoscopy was not used, and the procedure was performed percutaneously under direct ultrasound visualization. ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(86)90613-7

    authors： Berkowitz RL,Chitkara U,Goldberg JD,Wilkins I,Chervenak FA

    更新日期：1986-03-01 00:00:00

  • Cesarean section deliveries among adolescent mothers enrolled in a comprehensive prenatal care program.

    abstract：:A comparison was made of the incidences of cesarean section deliveries between mothers 18 years of age or younger and those 19 to 21 years of age, all of whom were enrolled in a comprehensive program of prenatal care. Also compared were the indications for surgical delivery between the two groups. The rate of cesarean...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(85)80033-8

    authors： Leppert PC,Namerow PB,Horowitz E

    更新日期：1985-07-15 00:00:00

  • In utero evaluation of fetal cardiac structure: a preliminary report.

    abstract：:Fetal echocardiography as a tool for the prenatal diagnosis of cardiac structural abnormalities was utilized in 27 consecutive patients who were referred for evaluation. Four abnormalities were recognized prenatally and confirmed postnatally. A fifth was identified postnatally. The sensitivity and specificity of this ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(84)90738-5

    authors： Nimrod C,Nicholson S,Machin G,Harder J

    更新日期：1984-03-01 00:00:00

  • Cigarette smoking, use of oral contraceptives, and myocardial infarction.

    abstract：:The excess risk of nonfatal myocardial infarction among users of oral contraceptives observed in England and Wales can be explained in terms of the high proportion of smokers in the study population. Among nonsmokers, the relative risk associated with the use of oral contraceptives is estimated to be 2 to 1, which is ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(76)90539-1

    authors： Jain AK

    更新日期：1976-10-01 00:00:00

  • Disposition of meperidine and normeperidine following multiple doses during labor. II. Fetus and neonate.

    abstract：:It has been suggested that continued diffusion gradients from mother to fetus would exist and that both meperidine and normeperidine would accumulate in the fetus following multiple doses of meperidine to the mother during labor. However, no pharmacokinetic data are available. Therefore, the purpose of this study was ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(85)90314-x

    authors： Kuhnert BR,Kuhnert PM,Philipson EH,Syracuse CD

    更新日期：1985-02-01 00:00:00

  • Ascending group B streptococcal genital infection in the rabbit model.

    abstract：OBJECTIVE:We investigated in a pregnant rabbit model the effects of intravaginal inoculation of type la group B streptococci and antibiotic intervention. STUDY DESIGN:We inoculated 10(4) to 10(6) cfu of type la group B streptococci into the upper vagina hysteroscopically at day 21 to 27 of a 31-day gestation. Initiall...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(96)70153-9

    authors： McDuffie RS Jr,Gibbs RS

    更新日期：1996-08-01 00:00:00

  • Selective termination: clinical experience and residual risks.

    abstract：:Assisted reproductive technologies have aided thousands of couples, but complications have resulted in multifetal pregnancies creating a bitter irony for infertility patients. In an effort to increase the rate of intact survival, we have successfully performed transabdominal first-trimester selective termination proce...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(90)90922-t

    authors： Evans MI,May M,Drugan A,Fletcher JC,Johnson MP,Sokol RJ

    更新日期：1990-06-01 00:00:00

  • Fetal renal volume assessment by three-dimensional ultrasonography.

    abstract：OBJECTIVE:This study was undertaken to measure fetal renal volume by means of three-dimensional ultrasonography and to use those data to establish the accurate constant and formula for fetal renal volume assessment with two-dimensional ultrasonography. STUDY DESIGN:Singleton fetuses between 15 and 40 weeks' gestation ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(00)70227-4

    authors： Hsieh YY,Chang CC,Lee CC,Tsai HD

    更新日期：2000-02-01 00:00:00

  • Prospective analysis of sperm-oocyte fusion and reactive oxygen species generation as criteria for the diagnosis of infertility.

    abstract：:We have undertaken a prospective analysis of the diagnostic significance of three different criteria of human sperm function including the conventional semen profile, measurements of hamster-oocyte fusion, and determinations of reactive oxygen species generation in 139 couples. The latter, who were characterized by a ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(11)80017-7

    authors： Aitken RJ,Irvine DS,Wu FC

    更新日期：1991-02-01 00:00:00

  • Use of the erythrocyte rosette test to screen for excessive fetomaternal hemorrhage in Rh-negative women.

    abstract：:The possibility of Rh immune globulin failure exists when a fetomaternal hemorrhage exceeds 25 to 30 ml of whole blood and only one 300 micrograms vial of Rh immune globulin is administered. In this prospective study of 1000 consecutive Rh-negative women who were delivered of Rh-positive newborn infants, the presence ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(86)90725-8

    authors： Stedman CM,Baudin JC,White CA,Cooper ES

    更新日期：1986-06-01 00:00:00

  • Evaluation of multiple-marker screening for Down syndrome in a statewide population.

    abstract：OBJECTIVE:Our purpose was to evaluate our experience with a statewide, multiple-marker Down syndrome screening program. STUDY DESIGN:The results of 18,712 screening tests performed from July 1, 1991, to Oct. 31, 1992, were reviewed. Amniocentesis and aneuploidy detection rates were compared with the experience of a pr...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(93)90007-6

    authors： Wenstrom KD,Williamson RA,Grant SS,Hudson JD,Getchell JP

    更新日期：1993-10-01 00:00:00

  • Neuroprotective peptides influence cytokine and chemokine alterations in a model of fetal alcohol syndrome.

    abstract：OBJECTIVE:Fetal alcohol syndrome (FAS) is associated with intellectual disability and neurodevelopmental abnormalities. Neuroprotective peptides NAPVSIPQ (NAP) and SALLRSIPA (SAL) can prevent some of the alcohol-induced teratogenesis including fetal death, growth abnormalities, and learning impairment in part by preven...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2012.10.005

    authors： Roberson R,Kuddo T,Benassou I,Abebe D,Spong CY

    更新日期：2012-12-01 00:00:00

  • Grand multiparity: an obstetric or neonatal risk factor?

    abstract：:Grand multiparity has been considered to be a factor in maternal and neonatal morbidity. In addition, families with seven or more children have been associated with low socioeconomic status. To minimize the confounding effect of the socioeconomic status, the outcome of grand multiparity has been investigated in a most...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(88)90213-x

    authors： Seidman DS,Armon Y,Roll D,Stevenson DK,Gale R

    更新日期：1988-05-01 00:00:00

  • Impaired KATP channel function in the fetoplacental circulation of patients with type 1 diabetes mellitus.

    abstract：OBJECTIVE:The increased perinatal morbidity in diabetes may be partly related to vascular dysfunction. Because potassium channels play an important role in the regulation of vascular tone, this study explores the impact of diabetes on potassium channel function in the fetoplacental vascular bed. STUDY DESIGN:Vascular ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2004.09.031

    authors： Bisseling TM,Versteegen MG,van der Wal S,Copius Peereboom-Stegeman JJ,Borggreven JM,Steegers EA,van der Laak JA,Russel FG,Smits P

    更新日期：2005-03-01 00:00:00

  • Nonimmune hydrops fetalis associated with angioosteohypertrophy (Klippel-Trenaunay) syndrome.

    abstract：:A case of nonimmune hydrops fetalis in association with angioosteohypertrophy (Klippel-Trenaunay) syndrome is reported for the first time. ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(88)90443-7

    authors： Mor Z,Schreyer P,Wainraub Z,Hayman E,Caspi E

    更新日期：1988-11-01 00:00:00

  • Phencyclidine use during pregnancy.

    abstract：:Phencyclidine, a frequently abused drug, has been shown to cross the placenta and may cause harmful effects in the fetus. Therefore, a prospective study was undertaken to determine the extent of phencyclidine use during pregnancy. Two thousand three hundred twenty-seven pregnant women were screened for phencyclidine u...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(84)80063-0

    authors： Golden NL,Kuhnert BR,Sokol RJ,Martier S,Bagby BS

    更新日期：1984-02-01 00:00:00