Safety of an IV formulation of carbamazepine.

Abstract:

:An intravenous formulation of carbamazepine (CBZ) was administered to 113 (60 male; 53 female) persons with epilepsy aged 19-87 years. Subjects received 100mg of study drug as replacement for 100mg of their usual morning dose of CBZ. There were no significant changes in blood pressure or heart rate suggesting that this formulation can be developed as replacement therapy for persons unable to take oral CBZ.

journal_name

Epilepsy Res

journal_title

Epilepsy research

authors

Conway JM,White JR,Birnbaum AK,Eugene Ramsay R,Pennell PB,Rarick JO,Musib L,Leppik IE,Cloyd JC

doi

10.1016/j.eplepsyres.2009.01.013

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

242-4

issue

2-3

eissn

0920-1211

issn

1872-6844

pii

S0920-1211(09)00021-7

journal_volume

84

pub_type

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