Abstract:
:Early epilepsy is known to worsen the developmental prognosis of young children with a congenital focal brain lesion, but its direct role is often very difficult to delineate from the other variables. This requires prolonged periods of follow-up with simultaneous serial electrophysiological and developmental assessments which are rarely obtained. We studied a male infant with a right prenatal infarct in the territory of the right middle cerebral artery resulting in a left spastic hemiparesis, and an epileptic disorder (infantile spasms with transient right hemihypsarrhythmia and focal seizures) from the age of 7 months until the age of 4 years. Pregnancy and delivery were normal. A dissociated delay of early language acquisition affecting mainly comprehension without any autistic features was documented. This delay was much more severe than usually expected in children with early focal lesions, and its evolution, with catch-up to normal, was correlated with the active phase of the epilepsy. We postulate that the epilepsy specifically amplified a pattern of delayed language emergence, mainly affecting lexical comprehension, reported in children with early right hemisphere damage.
journal_name
Dev Med Child Neuroljournal_title
Developmental medicine and child neurologyauthors
Mayor-Dubois C,Maeder-Ingvar M,Deonna T,Roulet-Perez Edoi
10.1111/j.1469-8749.2008.03162.xsubject
Has Abstractpub_date
2008-11-01 00:00:00pages
870-5issue
11eissn
0012-1622issn
1469-8749pii
DMCN3162journal_volume
50pub_type
杂志文章abstract:AIM:To elucidate the relation between motor impairment and other developmental deficits in very preterm-born children without disabling cerebral palsy and term-born comparison children at 5 years of (corrected) age. METHOD:In a prospective cohort study, 165 children (81 very preterm-born and 84 term-born)were assessed...
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abstract::Following the observation that many children with kwashiorkor had a deprived look in their eyes, the guardians of 107 children with kwashiorkor and 111 controls were interviewed about their home life, in a survey made at New Mulago Hospital, Kampala, between 1969 and 1972. A child's age, sex and tribe were found to ha...
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更新日期:2010-12-01 00:00:00
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journal_title:Developmental medicine and child neurology
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doi:
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journal_title:Developmental medicine and child neurology
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更新日期:2012-09-01 00:00:00
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更新日期:2002-04-01 00:00:00
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journal_title:Developmental medicine and child neurology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-11-01 00:00:00
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journal_title:Developmental medicine and child neurology
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更新日期:2010-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/S0012162206000922
更新日期:2006-06-01 00:00:00
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journal_title:Developmental medicine and child neurology
pub_type: 杂志文章
doi:10.1111/j.1469-8749.1988.tb04724.x
更新日期:1988-02-01 00:00:00
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doi:10.1017/s0012162203001488
更新日期:2003-12-01 00:00:00
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journal_title:Developmental medicine and child neurology
pub_type: 临床试验,杂志文章
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更新日期:2008-05-01 00:00:00
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更新日期:1989-08-01 00:00:00
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更新日期:2016-09-01 00:00:00
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更新日期:2007-12-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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doi:10.1111/j.1469-8749.2007.02008.x
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更新日期:1994-06-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2019-09-01 00:00:00