Protective effect of lycopene in cardiovascular disease.

Abstract:

:Coronary artery disease (CAD) represents the primary cause of death in Western Countries with an high incidence on human health and community social costs. Oxidative stress induced by reactive oxygen species (ROS) plays an important role in the aetiology of this disease. In particular, the LDL-oxidization has a key role in the pathogenesis of atherosclerosis and cardiovascular heart diseases through the initiation of plaque formation process. Dietary phytochemical products such antioxidant vitamins (A,C,E) and bioactive food components (alpha- and beta-carotene) have shown an antioxidant effect in reducing both oxidative markers stress and LDL-oxidization process. Scientifical evidences support the beneficial roles of phytochemicals in the prevention of some chronic diseases. Lycopene, an oxygenated carotenoid with great antioxidant properties, has shown both in epidemiological studies and supplementation human trials a reduction of cardiovascular risk. However, controlled clinical trials and dietary intervention studies using well-defined subjects population haven't been provided a clear evidence of lycopene in the prevention of cardiovascular diseases. The present short review aims to evaluate the beneficial effect of lycopene in the prevention of cardiovascular disease.

authors

Riccioni G,Mancini B,Di Ilio E,Bucciarelli T,D'Orazio N

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

183-90

issue

3

eissn

1128-3602

issn

2284-0729

journal_volume

12

pub_type

杂志文章,评审
  • Serum miR-629 is a novel molecular marker for diagnosis and the prognosis of pancreatic cancer.

    abstract:OBJECTIVE:Increasing evidence indicates that dysregulation of miRNAs is involved in tumor progression and development. We aimed to determine potential values of miR-629 as a serum diagnostic and prognostic biomarker in pancreatic cancer (PC). PATIENTS AND METHODS:MiR-629 expression levels in PC tissues and serum were ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201808_15715

    authors: Shi W,Lu Y,Gong R,Sun JJ,Liu G

    更新日期:2018-08-01 00:00:00

  • Analysis of changes in joint function and peripheral blood mononuclear cells in patients with systemic lupus erythematosus and intervention effects of different drugs.

    abstract:OBJECTIVE:To investigate the therapeutic effect of drug therapy with cyclophosphamide and leflunomide on the joint function damage of patients with systemic lupus erythematosus (SLE) and its regulatory effects on expression levels of programmed death receptor 1, Notch signaling pathway genes and interferon-inducible pr...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Zhou QS,Hu J,Hu H

    更新日期:2017-10-01 00:00:00

  • 3D cone beam (CBCT) in evaluation of frontal recess: findings in youth population.

    abstract:BACKGROUND:Frontal recess is the anatomical region most difficult to manage in endoscopic frontal sinus surgery due to the extreme variability of the cell patterns that may be observed in this area. CT has always been the gold standard in preoperative evaluation, but especially in the assessment of the causes of fronta...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Minni A,Messineo D,Attanasio G,Pianura E,D'Ambrosio F

    更新日期:2012-07-01 00:00:00

  • Menopause: new frontiers in the treatment of urogenital atrophy.

    abstract:OBJECTIVE:Urogenital atrophy is a degenerative process that may occur during menopause causing debilitating disorders and painful symptomatology. Estrogen therapy slows the onset of atrophy, but it requires ongoing therapy to maintain its effectiveness. To mitigate the degenerative evolutions associated with menopause,...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201801_14211

    authors: Casarotti GA,Chiodera P,Tremolada C

    更新日期:2018-01-01 00:00:00

  • Influence of sepsis on higher daily dose of amikacin pharmacokinetics in critically ill patients.

    abstract:BACKGROUND AND OBJECTIVES:Severe sepsis is a major problem as cause of high rates morbidity and mortality in intensive care units (ICU). Aminoglycosides are an important group of antimicrobials used for severe sepsis. However, aminoglycoside pharmacokinetics in ICU patients may be altered during sepsis, which can affec...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 临床试验,杂志文章

    doi:

    authors: Mahmoudi L,Mohammadpour AH,Ahmadi A,Niknam R,Mojtahedzadeh M

    更新日期:2013-02-01 00:00:00

  • Totally thoracoscopic surgery for atrial myxomas resection and atrial septal defect repair.

    abstract:OBJECTIVE:The purpose of this study is to compare the effectiveness and safety of thoracoscopic surgery and traditional median sternotomy. PATIENTS AND METHODS:64 patients with atrial myxoma and 114 patients with atrial septal defect were collected from Mar 2012 to Aug 2015. 40 atrial myxoma and 77 atrial septal defec...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Deng L,Zhang GW,Liu ZH,Meng WX,Liu HY

    更新日期:2017-02-01 00:00:00

  • Applied analysis of humanized nursing combined with wet healing therapy to prevent bedsore.

    abstract:OBJECTIVE:To analyze and evaluate the effects of humanized nursing combined with wet healing therapy to treat the stage II and III bedsores in hospitalized patients. PATIENTS AND METHODS:From March 2013 to July 2014 we enrolled fifty patients with stage II and III bedsores. They were randomly divided into control grou...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Luan XR,Li WH,Lou FL

    更新日期:2016-10-01 00:00:00

  • Perindopril inhibits myocardial apoptosis in mice with acute myocardial infarction through TLR4/NF-κB pathway.

    abstract:OBJECTIVE:To explore the anti-apoptotic effect of perindopril on myocardial cells in mice with acute myocardial infarction (AMI). MATERIALS AND METHODS:A total of 48 mice were randomly divided into 4 groups before intervention, namely sham operation group (Sham group, n=12), AMI group (n=12), 1.5 mg/kg perindopril tre...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201908_18558

    authors: Wang XZ,Yu ZX,Nie B,Chen DM

    更新日期:2019-08-01 00:00:00

  • FABP4 inhibitor attenuates inflammation and endoplasmic reticulum stress of islet in leptin receptor knockout rats.

    abstract:OBJECTIVE:Metabolic syndrome is characterized by abdominal obesity, hypertriglyceridemia and hyperglycemia. Fatty acid binding protein 4 (FABP4), as a member of intracellular lipid chaperones, is not only engaged in lipid transport but involved in inflammation and insulin resistance. The present study was to investigat...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202012_24182

    authors: Yao F,Jiang DD,Guo WH,Guo LS,Gao MM,Bai Y,Wang X,Zhang LS

    更新日期:2020-12-01 00:00:00

  • Surgical therapy of breast hypertrophy: a comparison of complications and satisfaction rate in large and small superior pedicle custom-made reduction mammaplasty.

    abstract:OBJECTIVE:The reduction mammaplasty is indicated for patients with symptomatic breast hypertrophy. Although surgery is considered the gold standard treatment, it is still debated which is the complication rate and whether or not there is an increased complication rate with increased tissue resection per breast. The mai...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Fino P,Di Taranto G,Toscani M,Scuderi N

    更新日期:2016-11-01 00:00:00

  • MiR-19a suppress apoptosis of myocardial cells in rats with myocardial ischemia/reperfusion through PTEN/Akt/P-Akt signaling pathway.

    abstract:OBJECTIVE:To detect differentially expressed micro ribonucleic acids (miRNAs) in rats with myocardial ischemia/reperfusion (MIR), and to explore the influence of miR-19a on MIR rats and its mechanism. MATERIALS AND METHODS:Firstly, the Sprague-Dawley (SD) rats were used to prepare MIR models, RNAs were extracted, and ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202003_20700

    authors: Ma Z,Lan YH,Liu ZW,Yang MX,Zhang H,Ren JY

    更新日期:2020-03-01 00:00:00

  • MicroRNA-130-5p promotes invasion as well as migration of lung adenocarcinoma cells by targeting the EZH2 signaling pathway.

    abstract:OBJECTIVE:This study was designed to investigate whether microRNA-130-5p could promote the progression and metastasis of lung cancer by targeting enhancer of zeste homolog 2 (EZH2). PATIENTS AND METHODS:The level of microRNA-130-5p was examined in the tumor tissues and paracancerous tissues of lung adenocarcinoma pati...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201911_19442

    authors: Zhang G,Wu YJ,Yan F

    更新日期:2019-11-01 00:00:00

  • 13C-octanoic acid breath test to study gastric emptying time.

    abstract::Digestion is a complex process regulated by several factors. Among these, one of the most important is the time of gastric emptying. A delayed gastric emptying time can be caused by several factors and can generate considerable discomfort in humans. It ranges from mild to real debilitating disorders. Until now, differ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Bruno G,Lopetuso LR,Ianiro G,Laterza L,Gerardi V,Petito V,Poscia A,Gasbarrini A,Ojetti V,Scaldaferri F

    更新日期:2013-01-01 00:00:00

  • Possible treatment and strategies for COVID-19: review and assessment.

    abstract::The coronavirus disease 2019 (COVID-19) is declared as an international emergency in 2020. Its prevalence and fatality rate are rapidly increasing but the medication options are still limited for this perilous disease. The emergent outbreak of COVID-19 triggered by severe acute respiratory syndrome coronavirus 2 (SARS...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:10.26355/eurrev_202012_24057

    authors: Trivedi N,Verma A,Kumar D

    更新日期:2020-12-01 00:00:00

  • The accuracy of CBCT in measuring jaws bone density.

    abstract:BACKGROUND:The cone-beam computerized tomography (CBCT) has become widely used for oral and maxillofacial imaging, providing a good spatial resolution, gray density range, and contrast, as well as a good pixel/noise ratio. In the CBCT the dimensional accuracy is also comparable with Computer Tomography (CT), but in con...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Cassetta M,Stefanelli LV,Di Carlo S,Pompa G,Barbato E

    更新日期:2012-10-01 00:00:00

  • Self-protection of medical workers in ophthalmology clinic during COVID-19 epidemic.

    abstract::Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by a coronavirus called SARS Coronavirus 2 (SARS-CoV-2). It has been observed that COVID-19 mainly spreads via respiratory tract, contact and digestive tract. Due to the particularity of profession, ophthalmic medical workers need to be in close conta...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202005_21210

    authors: Hua L,Zhu H,Liu H

    更新日期:2020-05-01 00:00:00

  • MiR-21 relieves rheumatoid arthritis in rats via targeting Wnt signaling pathway.

    abstract:OBJECTIVE:To investigate the influence of micro ribonucleic acid (miR)-21 on rats with rheumatoid arthritis (RA) through the Wnt signaling pathway. MATERIALS AND METHODS:A total of 30 rats were divided into three groups: control group (healthy rats, n=10), model group (rat model of RA, n=10), and MiR group (rat model ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201908_18635

    authors: Liu XG,Zhang Y,Ju WF,Li CY,Mu YC

    更新日期:2019-08-01 00:00:00

  • Nitric oxide mediated effects of nebivolol in myocardial infarction: the source of nitric oxide.

    abstract:OBJECTIVE:After MI pathological LV remodeling is one of the major causes of death. We previously showed the NO mediated beneficial effects of nebivolol in rat MI model, in this study we aimed to evaluate the NOS related mechanisms in this phenomenon. MATERIALS AND METHODS:Rats were divided into four groups: sham opera...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Mercanoglu G,Safran N,Ahishali B B,Uzun H,Yalcin A,Mercanoglu F

    更新日期:2015-12-01 00:00:00

  • Anti IgE antibody as treatment of allergic bronchopulmonary aspergillosis in a patient with cystic fibrosis.

    abstract::Allergic bronchopulmonary aspergillosis (ABPA) occurs in 7-9% of patients with cystic fibrosis (CF) and causes a worsening of lung function and respiratory symptoms. Standard treatment of ABPA consists of oral steroids; however, higher corticosteroid therapy associated to antifungal agent (itraconazole) long-term trea...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Zicari AM,Celani C,De Castro G,Valerio De Biase R,Duse M

    更新日期:2014-07-01 00:00:00

  • Imaging assessment of portal venous system: pictorial essay of normal anatomy, anatomic variants and congenital anomalies.

    abstract::The purpose of this pictorial essay is to describe anatomic variants and congenital anomalies of portal venous system and related liver parenchymal alterations. The imaging findings of some of these entities have been previously described in other articles, however this work encompasses all congenital anomalies of por...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Guerra A,De Gaetano AM,Infante A,Mele C,Marini MG,Rinninella E,Inchingolo R,Bonomo L

    更新日期:2017-10-01 00:00:00

  • p-CREB-1 at Ser 133 is a potential marker for breast cancer.

    abstract:OBJECTIVE:Dysregulation of numerous oncogenes and their downstream signaling pathways, among others in the signaling transduction molecule p-CREB-1 (p-cAMP responsive element binding protein-1), is an essential feature of different types of cancer. To investigate whether p-CREB-1 is also pivotal in tumorigenesis and me...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202011_23806

    authors: Xin ZC,Hu HW,Lao ZH,Zhu LQ,Biskup E,Zhang HW

    更新日期:2020-11-01 00:00:00

  • Obstructive sleep apnea syndrome in the pediatric age: the role of the pneumologist.

    abstract:OBJECTIVE:This review paper aims to summarize the current state of knowledge on the role of the pneumologist in the diagnosis and respiratory treatment of children affected by obstructive Sleep Disordered Breathing (SDB). MATERIALS AND METHODS:A literature review has been performed on the following topics: obstructive...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:10.26355/eurrev_201903_17342

    authors: Toraldo DM,Di Michele L,Ralli M,Arigliani M,Passali GC,De Benedetto M,Passali D

    更新日期:2019-03-01 00:00:00

  • Screening of differentially expressed genes of middle cerebral artery occlusion with DNA microarray.

    abstract:OBJECTIVES:To screen differentially expressed genes of different days after cerebral artery occlusion and drug treatment, and identify related small drug molecules. MATERIALS AND METHODS:The gene expression profile GSE35338 of cerebral artery occlusion was downloaded from Gene Expression Omnibus database, including a ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Zhang YD,Gu XH,Dai RY,Chen Z,Zhou J,He XZ,Wu H,Yang HJ,Zhang YH

    更新日期:2013-05-01 00:00:00

  • Effect of pioglitazone combined with simvastatin on the CD40-CD40 ligand system in rabbits with atherosclerosis.

    abstract:OBJECTIVE:This paper aims to investigate the interaction mechanism between pioglitazone/simvastatin and the CD40-CD40 ligand (CD40-CD40L) system and to determine their interaction effects on atherosclerosis in rabbits. MATERIALS AND METHODS:Forty rabbits were randomly divided into five groups of eight: normal control,...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Xue L,Zhu XH,Yang XF,Bao XC,Gao XQ,Qiu YH,Wu Z,Ji XP,Li HW

    更新日期:2015-01-01 00:00:00

  • Effect of melatonin and n-acetylcysteine on hepatic injury in rat induced by methanol intoxication: a comparative study.

    abstract:BACKGROUND:Methanol intoxication leads liver injury; in contrast melatonin and n-acetyl cysteine (NAC) are known to have protective effects on liver. AIM:We aimed to investigate the ultrastructural effects of melatonin and NAC on livers of methanol intoxicated rats and compare potential protective effects of melatonin...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Koksal M,Kurcer Z,Erdogan D,Iraz M,Tas M,Eren MA,Aydogan T,Ulas T

    更新日期:2012-04-01 00:00:00

  • Diet and pancreatic cancer: many questions with few certainties.

    abstract:UNLABELLED:BACKGROUND, OBJECTIVES: Pancreatic cancer ranks fourth for cancer mortality for men and women in the United States. This is a particularly devastating cancer since the case-fatality proportion approaches 90% within 12 months following diagnosis. Therefore, understanding the etiology and identifying the risk ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Cappellani A,Cavallaro A,Di Vita M,Zanghi A,Piccolo G,Lo Menzo E,Cavallaro V,Malaguarnera M,Giaquinta A,Veroux M,Cimino L,Berretta M

    更新日期:2012-02-01 00:00:00

  • A new association between hyaluronic acid and collagenase in wound repair: an open study.

    abstract:BACKGROUND:Most ulcers occur with slough and need debridement treatment. Surgical treatment is usually performed but many patients need an additional chemical therapy to promote healing process. This type of wound bed preparation is slower than surgical one, but it is essential in those patients who are not eligible fo...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Onesti MG,Fioramonti P,Carella S,Fino P,Sorvillo V,Scuderi N

    更新日期:2013-01-01 00:00:00

  • Antimicrobial activity of a 48-kDa protease (AMP48) from Artocarpus heterophyllus latex.

    abstract:BACKGROUND AND OBJECTIVE:Artocarpus heterophyllus (jackfruit) is a latex producing plant. Plant latex is produced from secretory cells and contains many intergradients. It also has been used in folk medicine. This study aimed to purify and characterize the biological activities of a protease from jackfruit latex. MATE...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Siritapetawee J,Thammasirirak S,Samosornsuk W

    更新日期:2012-01-01 00:00:00

  • Nanoscale bubble delivered YCD-TK/Cx26 gene therapeutic system suppresses tumor growth by inducing necrosis of tumor tissues in mouse Xenograft bladder cancer models.

    abstract:OBJECTIVE:Bladder cancer is considered as the fifth most common cancer in the whole world. This study aimed to investigate the anti-tumor effects of Nanoscale bubbles delivered yeast cytosine deaminase thymidine kinase/connexin 26 (YCD-TK/Cx26) on tumor cell proliferation and tumor growth. MATERIALS AND METHODS:Nanosc...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201909_18839

    authors: Fu YR,Luo Y,Xie X,Lu W,Zhang R,Xiong B,Chen F

    更新日期:2019-09-01 00:00:00

  • Effects of vitamin D levels on asthma control and severity in pre-school children.

    abstract:OBJECTIVE:Prevalence of asthma and vitamin D deficiency has been increasing and leading to significant morbidities. This study aimed to compare the vitamin D levels in the pre-school children with asthma and in healthy controls and to assess the relationship between vitamin D levels and asthma clinical parameters and c...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Turkeli A,Ayaz O,Uncu A,Ozhan B,Bas VN,Tufan AK,Yilmaz O,Yuksel H

    更新日期:2016-01-01 00:00:00