Abstract：
:This study reviewed different types of primary cardiac and mediastinal tumors in infants and children as well as their clinical presentation and management. Altogether, 34 consecutive patients followed from 1976 through December 2005 were analyzed. Of these 34 patients, 14 (41%) underwent surgery and 20 (59%) with rhabdomyomas were managed conservatively. Histologic examination of the surgically resected tumors showed teratoma in four patients, rhabdomyoma in four patients, and hemangioma in two patients. Myxoma, myofibroma, neuroblastoma, and malignant fibrous histiocytoma were encountered in one patient each. Follow-up evaluation was completed for 97% of the patients and extended up to 30 years. Half of the nonsurgical patients with rhabdomyoma showed partial or complete spontaneous regression. One patient died after resection of a malignant histiocytoma, and one patient required a tumor-related reoperation. Freedom from tumor-related reoperation after 10 years was 91% +/- 8.7%. Of the survivors, 85% were New York Heart Association (NYHA) class 1, and 100% had sinus rhythm. Spontaneous tumor regression is common in rhabdomyoma and surgery, and is indicated only for symptomatic patients with hemodynamically significant intracardiac obstruction. For all other benign primary cardiac tumors, complete resection usually can be accomplished with good results. Patients with giant tumor masses compressing or infiltrating the heart frequently cannot undergo complete resection. For these patients, restoration/preservation of sufficient heart function is the primary goal. Malignant tumors are extremely rare in pediatric patients and have a very poor prognosis.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Günther T,Schreiber C,Noebauer C,Eicken A,Lange Rdoi
10.1007/s00246-008-9256-6subject
Has Abstractpub_date
2008-11-01 00:00:00pages
1071-6issue
6eissn
0172-0643issn
1432-1971journal_volume
29pub_type
杂志文章abstract：:Exercise testing can highlight repolarisation abnormalities in adults with coronary artery disease. Late after Kawasaki disease (KD), increased QT dispersion (QTd) has been reported on resting ECG in children, but there are no reported studies of QTd during exercise. Our objective was to determine the pattern of QTd r...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0201-3
更新日期：2012-06-01 00:00:00
abstract：:We analyzed early and late results of surgical treatment of 100 consecutive children with Down's syndrome (DS) and congenital heart defect (CHD) who were operated on between 1990 and 1997. Fifty had common atrioventricular canal (CAVC), 24 ventricular septal defect, 8 the ostium primum atrial septal defect, 8 tetralog...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900483
更新日期：1999-09-01 00:00:00
abstract：:A 9-year-old girl was admitted because she had had palpitations for 2 years. Her electrocardiogram revealed multifocal ectopic beats with left bundle branch morphology, sinoatrial block, and first- and second-degree atrioventricular blocks. Cross-sectional echocardiography demonstrated an enlarged left ventricle and f...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02505810
更新日期：1996-01-01 00:00:00
abstract：:The single right ventricle (RV) in hypoplastic left heart syndrome (HLHS) often develops systolic dysfunction with time and this affects prognosis. Mechanical dyssynchrony has been reported in HLHS but has not consistently correlated with systolic function or electrical dyssynchrony. The aims of this study were to ass...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-019-02091-6
更新日期：2019-06-01 00:00:00
abstract：:An atrial septal aneurysm (ASA) is an increasingly recognized entity that involves septal tissue significantly bulging into either atria instead of remaining in a relatively neutral position. ASAs may be described based on the length of the segment of atrial septal tissue involved as well as the distance and direction...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-2017-2
更新日期：2019-01-01 00:00:00
abstract：:Kearns-Sayre syndrome (KSS) is a rare mitochondrial disorder characterized by large-scale deletions of mitochondrial DNA. Neuromuscular and cardiac conduction systems are most commonly involved in these patients. Here, we discuss a 10-year-old patient with diabetes mellitus who presented in complete heart block leadin...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9040-z
更新日期：2008-05-01 00:00:00
abstract：:Mammalian cardiomyocytes withdraw from the cell cycle soon after birth. This process is called terminal differentiation. The c-kit, a receptor tyrosine kinase, is expressed on cardiomyocytes immediately after birth but for only a few days. In mice with genetic c-kit dysfunction, adult cardiomyocytes are phenotypically...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-008-9366-1
更新日期：2009-07-01 00:00:00
abstract：:Calculating pulmonary vascular resistance is important in many fields of medicine. Although the influence of hematocrit on calculated resistance has been known for many years, it is rare to find the appropriate corrections in published articles. This review discusses the relationship between viscosity and resistance a...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-011-9954-3
更新日期：2011-06-01 00:00:00
abstract：:We present two term neonates in which intravenous indomethacin usage was associated with successful closure of a persistently patent arterial duct. Both children had congenital heart disease with high pulmonary blood flow following surgical placement of contralateral systemic-pulmonary artery shunts. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-004-0886-z
更新日期：2005-09-01 00:00:00
abstract：:A case of aneurysmal enlargement of the right atrium was found accidentally during a routine examination. The patient was asymptomatic and free of palpitations or proven rhythm disturbances. The results of echocardiography, magnetic resonance imaging, and cardiac catheterization excluded cardiac malformation, which co...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900341
更新日期：1998-09-01 00:00:00
abstract：:Unilateral absence of a pulmonary artery is a rare anomaly. Patients may present with hemoptysis, recurrent respiratory infections, pulmonary hypertension, or congestive heart failure. This report describes the case of a missing right pulmonary artery associated with anomalous left pulmonary venous connection not prev...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-011-0110-x
更新日期：2012-01-01 00:00:00
abstract：:The objective of this investigation was to compare how two modes of positive pressure ventilation affect cardiac output, airway pressures, oxygenation, and carbon dioxide removal in children with congenital heart disease in the immediate postoperative period. The investigation used a one group pretest-post-test study ...
journal_title：Pediatric cardiology
pub_type： 临床试验,杂志文章
doi：10.1007/s002460010210
更新日期：2001-05-01 00:00:00
abstract：:Horseshoe lung is a rare malformation that is often associated with lung hypoplasia and/or vascular anomalies. We describe a 10-year-old girl with horseshoe lung and unique left pulmonary vein. This is the first reported case with this vascular feature. The patient presented with signs and symptoms of severe pulmonary...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-010-9735-4
更新日期：2010-08-01 00:00:00
abstract：:The purpose of the study was to evaluate school-age developmental and educational outcomes for children with and without a cardiac procedure in the first year of life to improve understanding of longer-term neurodevelopmental outcomes in children who have had a cardiac procedure for congenital heart disease, the most ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-2029-y
更新日期：2019-03-01 00:00:00
abstract：:Chylothorax is a well-described complication after cardiothoracic surgery in children. Medical nutritional therapy for chylothorax includes medium-chain triglyceride (MCT) formulas and reduction in enteral long-chain triglyceride intake to reduce chyle production. Human milk is usually eliminated from the diet of infa...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1393-8
更新日期：2016-08-01 00:00:00
abstract：:Embryonic development is a tightly regulated process, and many families of genes functions to provide a regulatory genetic network to achieve such a program. The homeobox genes are an extensive family that encodes transcription factors with a characteristic 60-amino acid homeodomain. Mutations in these genes or in the...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0179-x
更新日期：2012-08-01 00:00:00
abstract：:Patency of the ductus arteriosus (PDA) is a common finding in small premature infants. Recently pulsed-Doppler-cross sectional echocardiography (PD-CSE) has been successfully used in these patients. We report a case of a premature infant with an unusual PD-CSE pattern. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02279882
更新日期：1988-01-01 00:00:00
abstract：:Adult studies suggest a better functional outcome after aortic valve replacement with a pulmonary autograft compared with mechanical or homograft valves. Little is known about functional results after Ross surgery in growing children. This study reports formal exercise stress echocardiographic data from 26 pediatric R...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0218-7
更新日期：2012-06-01 00:00:00
abstract：:With improvements in technology and surgical technique, pediatric cardiologists are challenging surgeons to close symptomatic ventricular septal defects (VSDs) in ever smaller patients. Although delaying surgery may facilitate operative repair, early intervention decreases the period of time these patients require the...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9016-z
更新日期：2008-01-01 00:00:00
abstract：:Children and adolescents with congenital heart disease often do not have the opportunity, inclination, or education to participate in safe and effective exercise. The consequences of this behavioral pattern affect not only cardiopulmonary parameters, but also psychosocial factors, especially when lack of participation...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-020-02413-z
更新日期：2020-12-01 00:00:00
abstract：:The spectrum of cardiac anomalies in trisomy 18 typically includes septal defects and polyvalvular disease and only rarely complex malformations. We report the first case of trisomy 18 with truncus arteriosus type II. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00796330
更新日期：1994-05-01 00:00:00
abstract：:The authors hypothesized that prospective, systematic Internet searches could identify occurrences of sudden cardiac death (SCD) in athletes and would be useful for establishing a system of active surveillance. Weekly advanced Google searches of the Internet were conducted for cases of SCD in young athletes during a 1...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0717-1
更新日期：2013-01-01 00:00:00
abstract：:Coronary artery anatomy represents a challenging and, often, determining predictor of outcome in an arterial switch operation (ASO). Impact of specific coronary artery variants, such as single, intramural and inverted, on time-related events following ASO, is, yet, to be determined. We sought to compare early and late...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1543-z
更新日期：2017-03-01 00:00:00
abstract：:We report a case of a 12-year-old boy with severe congenital aortic stenosis in whom magnetic resonance imaging (MRI) with delayed contrast enhancement demonstrated extensive subendocardial hyperenhancement within the left ventricle. The hyperenhancement was confirmed to be subendocardial infarct and fibrosis by histo...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-005-5891-3
更新日期：2006-05-01 00:00:00
abstract：:The aim of this study is to evaluate the relationship between maternal single nucleotide polymorphisms (SNPs) of methylenetetrahydrofolate reductase (MTHFR) gene with plasma homocysteine (HCY) level and offspring congenital heart diseases (CHDs). 338 mothers with offspring CHDs as case group and 306 mothers of normal ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-020-02449-1
更新日期：2020-11-21 00:00:00
abstract：:Eighteen of 25 survivors of aortic valvotomy in infancy were reinvestigated by cross-sectional echocardiography a mean of 7.5 (2.3-13.4) years after surgery. They had been operated at a median age of 38 (5-330) days. At the follow-up examination the gradient across the aortic valve was 41 +/- 19 (15-85) mmHg and the e...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00788221
更新日期：1992-01-01 00:00:00
abstract：:Device closure of atrial septal defects (ASDs) is rapidly becoming routine in children. Comparisons are often made to older surgical series with higher morbidities. However outcomes including reintervention, late failure, and the need for long-term follow-up must be considered and compared to those of a current surgic...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-002-0131-6
更新日期：2003-09-01 00:00:00
abstract：:Aortopulmonary window coexisting with tetralogy of Fallot (TF) was prospectively diagnosed by two-dimensional (2D) echocardiography and Doppler in an 18-month-old boy; the diagnosis was confirmed by cardiac catheterization and angiocardiography. Surgical correction was performed, but the patient died in the operating ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02239546
更新日期：1990-01-01 00:00:00
abstract：:This study aimed to assess the technical aspects of atrial septal defect (ASD) closure using the Amplatzer septal occluder (ASO) and the Gore Helex septal occluder (GHSO) for infants weighing less than 8 kg and to determine the safety, effectiveness, and near-to-intermediate-term outcome of the closure. The Mid-Atlant...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-014-0905-7
更新日期：2014-10-01 00:00:00
abstract：:A 6-year-old girl was found to have a combination of accessory mitral valve tissue and subaortic membrane. The association caused left ventricular outflow tract obstruction leading to severe left ventricular dysfunction. Surgical relief of the obstruction resulted in immediate improvement of ventricular function. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-001-5023-7
更新日期：2002-01-01 00:00:00
