Abstract：
:One often compares cells to computers, and signalling proteins to transistors. Location and wiring of those molecular transistors is paramount in defining the function of the subcellular chips. The bacterial chemotactic sensing apparatus is a large, stable assembly consisting of thousands of receptors, signal transducing kinases and linking proteins, and is responsible for the motile response of the bacterium to environmental signals, whether chemical, mechanical, or thermal. Because of its rich functional repertoire despite its relative simplicity, this chemosome has attracted much attention from both experimentalists and theoreticians, and the bacterial chemotaxis response becoming a benchmark in Systems Biology. Structural and functional models of the chemotactic device have been developed, often based on particular assumptions regarding the topology of the receptor lattice. In this issue of Molecular Microbiology, Briegel et al. provide a detailed view of the receptor arrangement, unravelling the wiring of the molecular signal processors.
journal_name
Mol Microbioljournal_title
Molecular microbiologyauthors
Shimizu TS,Le Novère Ndoi
10.1111/j.1365-2958.2008.06240.xsubject
Has Abstractpub_date
2008-07-01 00:00:00pages
5-9issue
1eissn
0950-382Xissn
1365-2958pii
MMI6240journal_volume
69pub_type
评论,杂志文章abstract：:Intimin and Invasin are prototypical inverse (Type Ve) autotransporters and important virulence factors of enteropathogenic Escherichia coli and Yersinia spp. respectively. In addition to a C-terminal extracellular domain and a β-barrel transmembrane domain, both proteins also contain a short N-terminal periplasmic do...
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journal_title：Molecular microbiology
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doi：10.1111/j.1365-2958.2011.07631.x
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journal_title：Molecular microbiology
pub_type： 评论,杂志文章
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.1992.tb01542.x
更新日期：1992-04-01 00:00:00
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journal_title：Molecular microbiology
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pub_type： 杂志文章
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doi：10.1111/j.1365-2958.2007.05991.x
更新日期：2007-12-01 00:00:00
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doi：10.1111/j.1365-2958.1994.tb01300.x
更新日期：1994-11-01 00:00:00
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pub_type： 杂志文章
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journal_title：Molecular microbiology
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更新日期：2001-03-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
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更新日期：2007-03-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.1996.tb02566.x
更新日期：1996-08-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
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更新日期：1995-04-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1046/j.1365-2958.1997.5971972.x
更新日期：1997-11-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1046/j.1365-2958.1997.4791844.x
更新日期：1997-08-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/mmi.12083
更新日期：2013-01-01 00:00:00
