Abstract:
:In this study, zebrafish eggs were exposed to a relatively low concentration (50 pg/mL) of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) for 72 h and then transferred to vehicle/TCDD-free water for the remainder of the experiments. Mortality, heart rates, edema severity, CYP1A, and regucalcin gene expressions were investigated to study TCDD-induced toxicity in zebrafish during the early life stage. Results indicated that the 50 pg/mL TCDD caused severe and visible developmental toxicity. Further research of the long term and low concentration of TCDD exposure is required.
journal_name
Bull Environ Contam Toxicoljournal_title
Bulletin of environmental contamination and toxicologyauthors
Wu YD,Jiang L,Zhou Z,Zheng MH,Zhang J,Liang Ydoi
10.1007/s00128-008-9395-8subject
Has Abstractpub_date
2008-06-01 00:00:00pages
482-6issue
6eissn
0007-4861issn
1432-0800journal_volume
80pub_type
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