Incidence of postoperative infections in non-immunocompromised pediatric patients with low absolute neutrophil counts preoperatively.

Abstract:

PURPOSE:To discover the incidence of postoperative surgical site infections in non-immunocompromised pediatric patients with an absolute neutrophil count (ANC) < or = 1,000 preoperatively. METHODS:Office and hospital charts of consecutive patients with preoperative ANC < or = 1,000 undergoing elective surgery over a three-year period were reviewed for evidence of postoperative surgical site infection. RESULTS:Six of 200 patients with preoperative ANCs < or = 1,000 developed a postoperative surgical site infection, an infection rate of 3.0%. One of 35 patients with preoperative ANCs < or = 500 developed a surgical site infection. The mean ANC of the study population was 800 (range 200 to 1,000); the mean ANC of the group with postoperative infection likewise was 800 (range 500 to 1,000). CONCLUSIONS:There was a postoperative surgical site infection rate of 3.0% in non-immunocompromised children who had a preoperative ANC < or = 1,000, similar to the overall surgical site infection rate in children. Cancellation of elective procedures in non-immunocompromised children with ANC < or = 1,000 is not warranted on the grounds of concern about postoperative infection.

journal_name

Surg Infect (Larchmt)

journal_title

Surgical infections

authors

Taylor GS,Cartwright PC,Snow BW

doi

10.1089/sur.2006.085

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

179-82

issue

2

eissn

1096-2964

issn

1557-8674

journal_volume

9

pub_type

杂志文章
  • Cost-effectiveness model of empiric doripenem compared with imipenem-cilastatin in ventilator-associated pneumonia.

    abstract:BACKGROUND:Ventilator-associated pneumonia (VAP) is a common complication of critical illness among surgical and trauma patients. Inappropriate empiric treatment of VAP increases the mortality rate. The rates of Pseudomonas aeruginosa (PA) VAP susceptibility to doripenem (DOR) are higher than those to imipenem-cilastat...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2009.076

    authors: Zilberberg MD,Mody SH,Chen J,Shorr AF

    更新日期:2010-10-01 00:00:00

  • Pediatric Sepsis Update: How Are Children Different?

    abstract:BACKGROUND:Although there are some commonalities between pediatric and adult sepsis, there are important differences in pathophysiology, clinical presentation, and therapeutic approaches. The recognition and diagnosis of sepsis is a significant challenge in pediatric patients as vital sign aberrations and examination f...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2017.316

    authors: Emr BM,Alcamo AM,Carcillo JA,Aneja RK,Mollen KP

    更新日期:2018-02-01 00:00:00

  • Decreased neutrophil response in a model of chronic intraperitoneal Klebsiella infection.

    abstract:BACKGROUND:Previously, we developed an infection model by intraperitoneal (IP) injection of Klebsiella pneumoniae. The high early mortality rate prompted a study of the effect of gentamicin on the disease course. METHODS:Infection was induced in Balb/c mice by IP inoculation of 10(3) colony-forming units (cfu) of K. p...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2006.060

    authors: Woods DR,Peyton JC,Franklin GA,Turina M,Cheadle WG

    更新日期:2007-06-01 00:00:00

  • Nasal carriage of Staphylococcus aureus among surgeons and surgical residents: a nationwide prevalence study.

    abstract:BACKGROUND:Staphylococcus aureus nasal carriage is an independent risk factor for developing nosocomial infections and for developing surgical site infection (SSI) in particular. The number of post-operative nosocomial S. aureus infections can be reduced by screening patients and decolonizing nasal carriers. In additio...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2014.022

    authors: van Vugt JL,Coelen RJ,van Dam DW,Winkens B,Derikx JP,Heddema ER,Stoot JH

    更新日期:2015-04-01 00:00:00

  • Clinical and economic consequences of post-operative infections following major elective surgery in U.S. hospitals.

    abstract:BACKGROUND:The incidence and consequences of post-operative infections in patients undergoing major elective surgery is not well understood. METHODS:Using a large U.S. healthcare claims database, we identified all patients who underwent major elective surgery between January 1, 2007, and December 31, 2009. For each su...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2012.200

    authors: Berger A,Edelsberg J,Yu H,Oster G

    更新日期:2014-06-01 00:00:00

  • Spread of Hand Infection According to the Site of Entry and Its Impact on Treatment Decisions.

    abstract:: Background: Hand infections can spread quickly and destroy functional structures. Early diagnosis and adequate therapy can prevent severe morbidities. The aim of this study was to evaluate systematically the spread of hand infections according to injury mechanism, pathogen...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2020.035

    authors: Dastagir K,Vehling M,Könneker S,Bingoel AS,Kaltenborn A,Jokuszies A,Vogt PM

    更新日期:2020-07-28 00:00:00

  • Combined Strategy for Post-Operative Patients with Central Nervous System Infections Caused by Extensively Drug-Resistant/Pan-Drug-Resistant Acinetobacter baumannii: A Retrospective Study.

    abstract:: Background: Post-operative central nervous system infections (PCNSIs) caused by extensively drug-resistant (XDR) or pan-drug-resistant (PDR) Acinetobacter baumannii are rare but intractable problems. To investigate a potential combined strategy to treat Acinetobacter bauma...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2019.341

    authors: Chang JB,Chen Y,Wang H,Ma X,Zhang X,Wu H,Ma B,Zuo W,Ma W,Wang R,Wei J

    更新日期:2020-12-01 00:00:00

  • Analysis of plasma citrulline and intestinal morphometry in mice with hepatosplenic schistosomiasis.

    abstract:BACKGROUND:Portal hypertension in the mucosa of the intestine and the presence of granulomas in the wall of this organ can alter digestive function in patients with schistosomiasis. Citrulline is a potential marker of intestinal function in some diseases that affect the morphometry of the mucosa because of its close as...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2009.066

    authors: Siqueira LT,Ferraz AA,Campos JM,De Lima Filho JL,Albuquerque MC,de Lima Aires A,Ribeiro MH,Cavalcanti MT,De Lima B Cavalcanti C,Ferraz EM

    更新日期:2010-10-01 00:00:00

  • Invasive mucormycosis and aspergillosis in a healthy 22-year-old battle casualty: case report.

    abstract:BACKGROUND:Invasive mucormycosis or aspergillosis is a life-threatening infection. The disease typically occurs in immunocompromised patients (e.g., those with diabetes mellitus or burns) but is rarely serious in otherwise-healthy young trauma patients. METHODS:Case report and literature review. RESULTS:A previously-...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2010.065

    authors: Radowsky JS,Strawn AA,Sherwood J,Braden A,Liston W

    更新日期:2011-10-01 00:00:00

  • Femoral Osteomyelitis Caused by Cladophialophora in a Patient without Known Immunocompromise.

    abstract:BACKGROUND:Chronic osteomyelitis associated with a stage IV decubitus ulcer is a challenging condition to manage, characterized by frequent relapses and need for long-term anti-microbial therapy. Although gram-positive cocci are the most common causes, fungal infections have been reported, usually in immunocompromised ...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2018.046

    authors: Jain NS,Horn CB,Coleoglou Centeno AA,Ilahi ON,Mazuski JE,Bocchichio GV,Punch LJ

    更新日期:2018-07-01 00:00:00

  • Influence of bronchoscopy on the diagnosis of and outcomes from ventilator-associated pneumonia.

    abstract:BACKGROUND:Ventilator-associated pneumonia (VAP) is a common healthcare-associated infection affecting as many as 27% of mechanically ventilated patients. Ventilator-associated pneumonia is an important source of morbidity and mortality in the surgical intensive care unit (SICU). The optimal diagnostic method for VAP h...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2013.142

    authors: Guidry CA,Mallicote MU,Petroze RT,Hranjec T,Rosenberger LH,Davies SW,Sawyer RG

    更新日期:2014-10-01 00:00:00

  • Resolution of clinical and laboratory abnormalities after diagnosis of ventilator-associated pneumonia in trauma patients.

    abstract:BACKGROUND:Guidelines advise that patients with ventilator-associated pneumonia (VAP) should respond clinically by Day 3 of antibiotics. White blood cell (WBC) count, maximum temperature (Tmax), and PaO2:FIO2 ratio are all said to respond significantly by Day 6. Resolution of abnormalities has not been evaluated in tra...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2011.128

    authors: Swanson JM,Connor KA,Magnotti LJ,Croce MA,Johnson J,Wood GC,Fabian TC

    更新日期:2013-02-01 00:00:00

  • Disseminated Nocardia farcinica: literature review and fatal outcome in an immunocompetent patient.

    abstract:BACKGROUND:Nocardia farcinica is a gram-positive, partially acid-fast, methenamine silver-positive aerobic actinomycete. Nocardia spp. are opportunistic pathogens, and N. farcinica is the least common species of clinical importance. METHODS:Review of the recent literature and description of a immunocompetent patient w...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2011.012

    authors: Budzik JM,Hosseini M,Mackinnon AC Jr,Taxy JB

    更新日期:2012-06-01 00:00:00

  • Fungal Isolates in Peritoneal Fluid Culture Do Not Impact Peri-Operative Outcomes of Peptic Ulcer Perforation.

    abstract:: Background: Fungal isolates from peritoneal fluid sampling in patients with perforated peptic ulcer (PPU) is not uncommon and its management unclear. This study aims to evaluate whether the presence of fungus in peritoneal fluid cultures is a predictor of morbidity and mor...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2019.024

    authors: Kwan JR,Lim M,Ng F,Shelat V

    更新日期:2019-12-01 00:00:00

  • Post-appendectomy surgical site infection rate after using an antimicrobial film incise drape: a prospective study.

    abstract:BACKGROUND:An appendectomy is a contaminated or potentially dirty surgical procedure that can be associated with surgical site infection (SSI). METHODS:A single-center unblinded prospective cohort study examined the role of antimicrobial incise film drapes in lowering the rate of SSI after appendectomy. Any patient ag...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2013.188

    authors: Al-Qahtani SM,Al-Amoudi HM,Al-Jehani S,Ashour AS,Abd-Hammad MR,Tawfik OR,Baslaim MM,Farrokhyar F

    更新日期:2015-04-01 00:00:00

  • Literature Review of Criteria for Defining Recipient-Site Infection after Oral Oncologic Surgery with Simultaneous Reconstruction.

    abstract:BACKGROUND:The lack of uniformity of criteria for defining recipient-site infection after oral oncologic surgery with simultaneous reconstruction is problematic despite numerous studies on this issue. This study aimed to investigate the difference in the criteria for defining recipient-site infection after oral oncolog...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2017.101

    authors: Akashi M,Kusumoto J,Sakakibara A,Hashikawa K,Furudoi S,Komori T

    更新日期:2017-10-01 00:00:00

  • A prospective evaluation of the use of emergency department computed tomography for suspected acute appendicitis.

    abstract:BACKGROUND:Computed tomography (CT) is used increasingly to evaluate suspected cases of acute appendicitis (AA) in the emergency department (ED). This prospective study was performed to test the hypothesis that the evaluation of AA by CT in the ED remains suboptimal and that erroneous interpretation diminishes its util...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/109629601317202687

    authors: Maluccio MA,Covey AM,Weyant MJ,Eachempati SR,Hydo LJ,Barie PS

    更新日期:2001-10-01 00:00:00

  • Positive sterility cultures of transplant solutions during pancreatic islet autotransplantation are associated infrequently with clinical infection.

    abstract:BACKGROUND:Chronic pancreatitis is a painful and often debilitating disease. Total pancreatectomy with intra-portal islet autotransplantation (TP-IAT) is a treatment option that allows for pain relief and preservation of beta-cell mass, thereby minimizing the complication of diabetes mellitus. Cultures of harvested isl...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2013.224

    authors: Colling KP,Blondet JJ,Balamurugan AN,Wilhelm JJ,Dunn T,Pruett TL,Sutherland DE,Chinnakotla S,Bellin M,Beilman GJ

    更新日期:2015-04-01 00:00:00

  • Trends in postoperative sepsis: are we improving outcomes?

    abstract:BACKGROUND AND PURPOSE:Each year, as many as two million operations are complicated by surgical site infections in the United States, and surgical patients account for 30% of patients with sepsis. The purpose of this study was to determine recent trends in sepsis incidence, severity, and mortality rate after surgical p...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2008.046

    authors: Vogel TR,Dombrovskiy VY,Lowry SF

    更新日期:2009-02-01 00:00:00

  • Effectiveness of pre-operative cefazolin in obese patients.

    abstract:BACKGROUND:Cefazolin remains the preferred preoperative antibiotic for the majority of surgical procedures. However, outcome evidence supporting current dosing recommendations for pre-operative prophylaxis is scarce, particularly for obese patients. With more than 33% of adults in the United States classified as obese,...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2012.167

    authors: Unger NR,Stein BJ

    更新日期:2014-08-01 00:00:00

  • Scoring System to Predict the Risk of Surgical Site Infection in Patients with Esophageal Cancer after Esophagectomy with Cervical Anastomosis.

    abstract:BACKGROUND:Surgical site infection (SSI) surveillance has become increasingly important during the peri-operative period of esophagectomy with cervical anastomosis (McKeown esophagectomy). This study sought to clarify the risk factors for SSI and to develop a stratification scoring system to predict SSI after esophagec...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2018.051

    authors: Yin LX,Chen BM,Zhao GF,Yuan QF,Xue Q,Xu K

    更新日期:2018-10-01 00:00:00

  • Antimicrobial resistance of Pseudomonas aeruginosa strains isolated from surgical infections in a 7-year period at a general hospital in Venezuela.

    abstract:BACKGROUND:By definition, the term "surgical infection" implies that surgery plays the major role in therapy, whereas antimicrobial chemotherapy is only supplementary. Despite this view, the efficacy of such drugs is relevant, and for this reason, drug activity surveillance is necessary, especially for opportunistic an...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2006.7.269

    authors: Rodriguez CN,Rodriguez-Morales AJ,Garcia A,Pastran B,Meijomil P

    更新日期:2006-06-01 00:00:00

  • Liver abscess as a complication of laparoscopic gastric banding bariatric surgery.

    abstract:BACKGROUND:The World Health Organization has identified the rapidly growing prevalence of obesity as one of today's serious health problems. Various surgical interventions categorized collectively as bariatric surgery now play an ever-increasing important role as the only known effective treatment for severe obesity. L...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2012.023

    authors: Garrido D,Bush LM

    更新日期:2013-10-01 00:00:00

  • Extrahepatic primary adrenal alveolar echinococcosis: a review.

    abstract:BACKGROUND:Primary echinococcosis, and especially primary alveolar echinococcosis (AE) is rare among adrenal lesions. METHODS:We report a case of primary AE in a 28-year-old male with low backache and occasional upper limb pain lasting for six months, and review the pertinent but sparse literature on this disorder. R...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2012.037

    authors: Chu ZG,Lv FJ,Zhu ZY,Ouyang Y

    更新日期:2013-08-01 00:00:00

  • Recommendations and reports about central venous catheter-related infection.

    abstract:BACKGROUND:Central venous catheters (CVCs) are used to deliver a variety of therapies, as well as for measurement of hemodynamic parameters. The major associated complication is catheter-related blood stream infection (CRBSI). METHOD:Review of the pertinent English-language literature. RESULTS:The incidence of CRBSI ...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2006.7.s2-65

    authors: Bacuzzi A,Cecchin A,Del Bosco A,Cantone G,Cuffari S

    更新日期:2006-01-01 00:00:00

  • Outcomes of Acinetobacter baumannii infection in critically ill surgical patients.

    abstract:BACKGROUND:Multi-drug resistant (MDR) organisms in intensive care units (ICUs) are a growing concern. The emergence of several infections with MDR Acinetobacter baumannii prompted a review of cases and evaluation of the efficacy of intervention. OBJECTIVE:To determine the rate of clinical cure, the incidence of drug r...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2006.029

    authors: Trottier V,Namias N,Pust DG,Nuwayhid Z,Manning R,Marttos AC Jr,Dunham MB,Schulman CI,McKenney MG

    更新日期:2007-08-01 00:00:00

  • Current Pneumonia Surveillance Methodology: Similar Underestimation in Trauma and Surgical Patients in the Intensive Care Unit.

    abstract:BACKGROUND:In 2013, the Centers for Disease Control and Prevention (CDC) developed new surveillance definitions for ventilator-associated events (VAE), leading to concerns that hospitals may be underreporting the true incidence of ventilator-associated pneumonias (VAPs). We sought to compare rates of clinically diagnos...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2016.152

    authors: Zosa BM,Golob JF,Conrad-Schnetz KJ,Schechtman D,Kreiner LA,Claridge JA

    更新日期:2017-07-01 00:00:00

  • Purpura fulminans managed with multi-limb amputation: substituted judgment and surrogate decision-making in the surgical management of necrotizing soft tissue infections.

    abstract:BACKGROUND:Purpura fulminans (PF) is a rare but lethal complication of severe infection. Aggressive surgical debridement of irreversibly devitalized tissue improves survival frequently at the cost of disfigurement. The ethical dilemma of surrogate decision-making for these often incapacitated patients presents a unique...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2013.223

    authors: Tanosaki M,Shimizu N,Lian CG,Jurchak M,Patel V

    更新日期:2014-12-01 00:00:00

  • The Challenge of Antimicrobial Resistance in Managing Intra-Abdominal Infections.

    abstract:BACKGROUND:In recent years, there has been a worldwide increase in infections caused by microorganisms resistant to multiple antimicrobial agents. METHODS:In the past few decades, an increased prevalence of infections caused by antibiotic-resistant pathogens, including Enterococcus spp., carbapenem-resistant Pseudomon...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2013.262

    authors: Sartelli M,Catena F,di Saverio S,Ansaloni L,Coccolini F,Tranà C,Kirkby-Bott J

    更新日期:2015-06-01 00:00:00

  • Pathogenesis of multiple organ dysfunction syndrome--endotoxin, inflammatory cells, and their mediators: cytokines and reactive oxygen species.

    abstract::Multiple organ dysfunction syndrome (MODS) is caused by an overwhelming, uncontrolled systemic inflammatory response that is activated by a number of hostile stimuli including sepsis, hypovolemic shock, and severe trauma resulting in massive tissue injury. The indiscriminate activation of the inflammatory response due...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/109629600750018123

    authors: Maier RV

    更新日期:2000-10-01 00:00:00