Pediatric Sepsis Update: How Are Children Different?

abstract：BACKGROUND:Most HIV-1 replication occurs in secondary lymphoid tissues, and evaluating these tissues is crucial to investigations of pathogenesis. Inguinal lymph nodes (LN) are obtained frequently for these studies as they are readily detectable in most individuals and provide abundant numbers of cells. Knowledge of th...

journal_title：Surgical infections

authors： Meditz AL,Connick E,McCarter M

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Cefazolin remains the preferred preoperative antibiotic for the majority of surgical procedures. However, outcome evidence supporting current dosing recommendations for pre-operative prophylaxis is scarce, particularly for obese patients. With more than 33% of adults in the United States classified as obese,...

journal_title：Surgical infections

authors： Unger NR,Stein BJ

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:There is a paucity of data regarding whether sterile handling of endotracheal tubes (ETTs) impacts the incidence and prevalence of pneumonia in the emergency, urgent, or elective clinical scenarios. Intensive care units employ infection control and reduction schemes to reduce pneumonia rates. METHODS:A MEDL...

journal_title：Surgical infections

authors： Cheung N,Betro G,Luckianow G,Napolitano L,Kaplan LJ

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Ventilator-associated pneumonia (VAP) is a common complication of critical illness among surgical and trauma patients. Inappropriate empiric treatment of VAP increases the mortality rate. The rates of Pseudomonas aeruginosa (PA) VAP susceptibility to doripenem (DOR) are higher than those to imipenem-cilastat...

journal_title：Surgical infections

authors： Zilberberg MD,Mody SH,Chen J,Shorr AF

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Temporary intra-operative portocaval shunts (TPCS) are believed to improve outcomes after cava-sparing liver transplantation. We hypothesize that decompression of the portal venous system via a TPCS reduces gut congestion, thereby decreasing bacterial translocation. Thus, we sought to clarify whether transpl...

journal_title：Surgical infections

authors： Weniger M,Andrassy J,Weig T,Grabein B,Crispin A,Rentsch M,Siebers C,Bazhin A,D'Haese JG,Hartwig W,Werner J,Guba M,Faist E,Pratschke S,Angele MK

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Nutritional status has major impacts on the outcome of surgery, in particular in patients with cancer. The aim of this review was to assess the merit of oral pre-operative nutritional support as a part of prehabilitation in patients undergoing surgery for colorectal cancer. METHODS:A systematic literature s...

journal_title：Surgical infections

authors： Bruns ERJ,Argillander TE,Van Den Heuvel B,Buskens CJ,Van Duijvendijk P,Winkels RM,Kalf A,Van Der Zaag ES,Wassenaar EB,Bemelman WA,Van Munster BC

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The emergence of multi-drug resistant microorganisms presents a critical problem for patients undergoing surgery. Acidic pH, which is produced by oxidized regenerated cellulose (ORC), is a broad-spectrum physiological detriment to survival of microorganisms known to cause surgical infections. The purpose of ...

journal_title：Surgical infections

authors： Spangler D,Rothenburger S,Nguyen K,Jampani H,Weiss S,Bhende S

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Solid organ transplantation (SOT) frequently is complicated by cytomegalovirus (CMV) infections. Cidofovir (CDV) is active against CMV, including many ganciclovir (GCV)-resistant mutants, but often is considered to be too nephrotoxic for use after organ transplantation. PATIENTS AND METHODS:Seven males and ...

journal_title：Surgical infections

authors： Bonatti H,Sifri CD,Larcher C,Schneeberger S,Kotton C,Geltner C

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Over the last half-decade, substantial breakthroughs have taken place in terms of routine therapy of critically ill patients. The combination of these strategies has the potential to result in improvement in the overall outcomes for patients in intensive care units. METHODS:A focused review was undertaken o...

journal_title：Surgical infections

authors： Beilman GJ

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Clostridium perfringens myonecrosis following an elective surgical procedure in a previously healthy child is a rare incident. METHODS:Case report and literature review. RESULTS:A two-year old boy admitted for elective bilateral osteotomies of tibiae was detected to be febrile at day one post-operatively w...

journal_title：Surgical infections

authors： Abd Rashid AH,Ramli R,Ibrahim S

更新日期：2014-10-01 00:00:00

abstract：: Background: Operating room (OR) traffic and door openings have emerged as potential modifiable risk factors for the development of surgical site infections. Methods: This study compared the microbial load of a Control OR withou...

journal_title：Surgical infections

authors： Lansing SS,Moley JP,McGrath MS,Stoodley P,Chaudhari AMW,Quatman CE

更新日期：2020-12-23 00:00:00

abstract：BACKGROUND:We investigated the clinical effectiveness of antimicrobial prophylaxis in lower-extremity open fractures following the Eastern Association for the Surgery of Trauma Guidelines. METHODS:This observational, retrospective, single-center study included adults with lower-extremity open fractures of the ankle, t...

journal_title：Surgical infections

authors： Bremmer D,Bookstaver B,Cairns M,Lindley K,Durkin M,Koon D,Quidley AM

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Severe trauma leads to hematopoietic failure and bone marrow (BM) dysfunction that manifests clinically as a persistent anemia and leukopenia. The impact of severe trauma and its associated hyperadrenergic state on erythropoiesis has not been described. The aim of this study was to demonstrate the effects of...

journal_title：Surgical infections

authors： Fonseca RB,Mohr AM,Wang L,Clinton E,Sifri ZC,Rameshwar P,Livingston DH

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Gentamicin is used commonly as an empiric antibiotic prior to culture evidence in the treatment of ventilator-associated pneumonia (VAP) in surgical patients. METHODS:The published literature on the use of gentamicin for empiric therapy in VAP was reviewed and in combination with the author's personal exper...

journal_title：Surgical infections

authors： Byrnes M,Dorman R

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Pre-existing humoral barriers challenge the transplantation of living donor kidneys (LDK) into highly sensitized ABO- and human leukocyte antigen (HLA)-incompatible recipients. Conditioning these LDK recipients' immune systems is required before they undergo transplantation. We hypothesized that medical dese...

journal_title：Surgical infections

authors： Turza KC,Shafique M,Lobo PI,Sawyer RG,Keith DS,Brayman KL,Agarwal A

更新日期：2014-06-01 00:00:00

abstract：: Background: A skin-sparing approach for the treatment of necrotizing soft-tissue infections (NSTIs) removes necrotic tissue planes while leaving viable overlying skin. Subsequent closure of the spared skin may decrease the need for graft-based reconstruction, which is asso...

journal_title：Surgical infections

authors： Tom LK,Maine RG,Wang CS,Parent BA,Bulger EM,Keys KA

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Nucleated red blood cells (NRBCs) are present in certain non-oncologic disease states and are associated with a poor prognosis. The purpose of this study was to evaluate NRBCs as an early prognostic marker for death in patients with surgical sepsis. METHODS:Retrospective evaluation of data collected prospec...

journal_title：Surgical infections

authors： Desai S,Jones SL,Turner KL,Hall J,Moore LJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Ventilator-associated pneumonia (VAP) is a common healthcare-associated infection affecting as many as 27% of mechanically ventilated patients. Ventilator-associated pneumonia is an important source of morbidity and mortality in the surgical intensive care unit (SICU). The optimal diagnostic method for VAP h...

journal_title：Surgical infections

authors： Guidry CA,Mallicote MU,Petroze RT,Hranjec T,Rosenberger LH,Davies SW,Sawyer RG

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Low plasma concentrations and genetic polymorphisms of mannan-binding lectin (MBL) have been associated with infectious disease complications during various conditions. The present study examined the nature and expression of MBL deficiency during a surgery-induced acute-phase response. METHODS:Blood was sam...

journal_title：Surgical infections

authors： Van Till JW,Boermeester MA,Modderman PW,Van Sandick JW,Hart MH,Gisbertz SS,Van Lanschot JJ,Aarden LA

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Patients with necrotizing soft tissue infections (NSTIs) require prompt surgical debridement, appropriate intravenous antibiotics, and intensive support. Despite aggressive treatment, their mortality and morbidity rates remain high. The benefit of hyperbaric oxygen (HBO) as an adjunctive treatment is controv...

journal_title：Surgical infections

authors： George ME,Rueth NM,Skarda DE,Chipman JG,Quickel RR,Beilman GJ

更新日期：2009-02-01 00:00:00

abstract：: Background: The greatest burden of sepsis- and septic shock-related morbidity and mortality is in low- and middle-income countries (LMICs). Accurate tracking of incidence and outcomes of patients in LMICs with sepsis has been limited by changing definitions, lack of diagno...

journal_title：Surgical infections

authors： Stephen AH,Montoya RL,Aluisio AR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Fungal sinusitis has been reported increasingly in immunocompetent patients. However, the most effective, appropriate mode of therapy has not been determined. MATERIALS AND METHODS:In this retrospective study, we examined the records of 110 immunocompetent patients with chronic sinusitis who had undergone s...

journal_title：Surgical infections

authors： Hadi U,Bitar M,Hachem R,Saade R,Husni R,Raad I

更新日期：2003-07-01 00:00:00

abstract：: Background: The use of mechanical bowel preparation and prophylaxis with oral antimicrobial agents can prevent surgical site infection (SSI) in colorectal surgical procedures, but routine adoption of these and other practices by surgeons has been limited. The aim of this s...

journal_title：Surgical infections

authors： Badia JM,Casey AL,Rubio-Pérez I,Arroyo-García N,Espin E,Biondo S,Balibrea JM

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The Donor Risk Index (DRI) is used to predict graft survival following liver transplantation, but has not been used to predict post-operative infections in graft recipients. We hypothesized that lower-quality grafts would result in more frequent infectious complications. METHODS:Using a prospectively collec...

journal_title：Surgical infections

authors： Rosenberger LH,Gillen JR,Hranjec T,Stokes JB,Brayman KL,Kumer SC,Schmitt TM,Sawyer RG

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Invasive mucormycosis or aspergillosis is a life-threatening infection. The disease typically occurs in immunocompromised patients (e.g., those with diabetes mellitus or burns) but is rarely serious in otherwise-healthy young trauma patients. METHODS:Case report and literature review. RESULTS:A previously-...

journal_title：Surgical infections

authors： Radowsky JS,Strawn AA,Sherwood J,Braden A,Liston W

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:This report presents a case of femoral osteomyelitis secondary to urinary tract infection in a female neonate with bilateral urinary duplication and right ectopic ureterocele. METHODS:A female neonate with a history of late perinatal sepsis presented to the emergency department and was found to have left dis...

journal_title：Surgical infections

authors： de Jesus LE,Fernandes A,Sias SM,de Mello CM,de Carvalho AM,Junior NC

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Computed tomography (CT) is used increasingly to evaluate suspected cases of acute appendicitis (AA) in the emergency department (ED). This prospective study was performed to test the hypothesis that the evaluation of AA by CT in the ED remains suboptimal and that erroneous interpretation diminishes its util...

journal_title：Surgical infections

authors： Maluccio MA,Covey AM,Weyant MJ,Eachempati SR,Hydo LJ,Barie PS

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:We aim to assess the patient factors and concomitant infectious outcomes associated with urinary tract infection (UTI) occurrence and the impact of UTI on length of stay (LOS), re-admission, and death in a colorectal surgical population. PATIENTS AND METHODS:National Surgical Quality Improvement Program Use...

journal_title：Surgical infections

authors： Armstrong JG,Li CH,Liao J,Byrn JC

更新日期：2017-07-01 00:00:00

abstract：: Background: In past decades, surgical site infections (SSIs) were neglected and not given much global attention in low- and middle-income countries (LMICs). The risk and incidence of SSIs in LMICs continue to increase. Methods: ...

journal_title：Surgical infections

authors： Seyi-Olajide JO,Ameh EA

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The designation "gram-positive bacillus" includes a variety of pleomorphic microorganisms, including diphtheroids, coryneform species, coccobacilli, and other small rods. Despite differing greatly in their virulence, sources, and even genus, these microscopically similar organisms are often difficult to diff...

journal_title：Surgical infections

authors： Clarke TM,Citron DM,Towfigh S

更新日期：2010-02-01 00:00:00