Pathogenesis of multiple organ dysfunction syndrome--endotoxin, inflammatory cells, and their mediators: cytokines and reactive oxygen species.

abstract：BACKGROUND:Antimicrobial resistance is a growing problem in the intensive care setting. This study was designed to evaluate the trends in bacterial prevalence and changes in antibiotic resistance at a large university hospital over the past decade. Antimicrobial resistance data were compared among the surgical intensiv...

journal_title：Surgical infections

authors： Franklin GA,Moore KB,Snyder JW,Polk HC Jr,Cheadle WG

更新日期：2002-07-01 00:00:00

abstract：: Background: Coronavirus 2019 (COVID-19) in the post-operative period is challenging. Its clinical manifestations may have similarities to other septic, thoracic, or gastrointestinal post-surgical complications. Additionally, the post-operative period may be a time of incre...

journal_title：Surgical infections

authors： Moliere S,Veillon F

更新日期：2020-06-01 00:00:00

abstract：: Background: Rates of infections with multi-drug-resistant organisms (MDROs) are increasing among critically ill patients. Among non-surgical patients, MDROs increase directly the risk of adverse secondary events including death. However, similar effects do not appear to oc...

journal_title：Surgical infections

authors： Rai I,Stephen AH,Lu Q,Heffernan DS

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Neutrophil dysfunction has been documented after injury in animals and human beings. This review evaluates the relative effects of the hormonal and endotoxin response to injury on immune resistance. METHOD:Review of the pertinent English-language literature. RESULTS:In volunteers given total parenteral nut...

journal_title：Surgical infections

authors： Parks KR,Davis JM

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Surgical site infection (SSI) continues to be a common if often times preventable infection. Considerable patient morbidity and economic cost are the consequences. METHODS:Review of the pertinent English-language literature. RESULTS:The National Surgical Infection Prevention (SIP) Project was an initiative...

journal_title：Surgical infections

authors： Fry DE

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:With high morbidity and potentially devastating consequences, surgical site infections (SSIs) after cardiac surgery add substantially to the healthcare burden. Inhibiting migration of skin microbes is likely to reduce contamination of the surgical incision by endogenous potential pathogens. We studied the ef...

journal_title：Surgical infections

authors： Dohmen PM,Weymann A,Holinski S,Linneweber J,Geyer T,Konertz W

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The use of silver for the treatment of various maladies or to prevent the transmission of infection dates back to at least 4000 b.c.e. Medical applications are documented in the literature throughout the 17th and 18th centuries. The bactericidal activity of silver is well established. Silver nitrate was used...

journal_title：Surgical infections

authors： Politano AD,Campbell KT,Rosenberger LH,Sawyer RG

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:It has been suggested that the damage observed in invasive amebiasis is related to interactions between polymorphonuclear leukocytes (PMN) and Entamoeba histolytica trophozoites. We analyzed the relation between infiltrating inflammatory cell populations and E. histolytica density in intestinal amebic lesion...

journal_title：Surgical infections

authors： Dickson-Gonzalez SM,de Uribe ML,Rodriguez-Morales AJ

更新日期：2009-04-01 00:00:00

abstract：:Broad-spectrum beta-lactam antibiotics have several advantages in the treatment of intra-abdominal infections. These agents are effective against gram-negative rods and anaerobes, reach therapeutic levels rapidly after parenteral administration, and, in the absence of penicillin allergy, generally exhibit low toxicity...

journal_title：Surgical infections

authors： Powell LL,Wilson SE

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The emergence of multi-drug resistant microorganisms presents a critical problem for patients undergoing surgery. Acidic pH, which is produced by oxidized regenerated cellulose (ORC), is a broad-spectrum physiological detriment to survival of microorganisms known to cause surgical infections. The purpose of ...

journal_title：Surgical infections

authors： Spangler D,Rothenburger S,Nguyen K,Jampani H,Weiss S,Bhende S

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Surgical care is delivered 24 h a day at most institutions. Alarmingly, some authors have found that certain operative start times are associated with greater morbidity and mortality rates. This effect has been noted in both the public and private sector. Although some of these differences may be related to ...

journal_title：Surgical infections

authors： Guidry CA,Davies SW,Willis RN,Dietch ZC,Shah PM,Sawyer RG

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Controversy continues to exist regarding the immunomodulatory effects of cellular blood transfusions in the fields of oncology, transplantation, and infectious diseases. Numerous studies have correlated transfusion with hospital-acquired infection, but the impact of transfusion on infection-related mortality...

journal_title：Surgical infections

authors： Hughes MG,Evans HL,Lightfoot L,Chong TW,Smith RL,Raymond DP,Pelletier SJ,Claridge JA,Pruett TL,Sawyer RG

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND AIM:Infection or bleeding after transrectal prostate biopsy remains a concern of both patients and urologists. We explored the risk of association of certain co-morbidities with both complications. PATIENTS AND METHODS:Using the Taiwan National Health Insurance Research Database, we identified patients ...

journal_title：Surgical infections

authors： Lin SL,Lin CT,Huang WT,Jou YC,Tzai TS,Tsai YS

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Ceftaroline fosamil is a novel cephalosporin approved by the United States Food and Drug Administration (US FDA) for treatment of acute bacterial skin and skin structure infection, including those caused by methicillin-resistant Staphylococcus aureus (MRSA). We evaluated the activity of ceftaroline and compa...

journal_title：Surgical infections

authors： Sader HS,Farrell DJ,Flamm RK,Jones RN

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The utility of hyperbaric oxygen therapy (HBOT) in the treatment of necrotizing soft tissue infections (NSTIs) has not been proved. Previous studies have been subject to substantial selection bias because HBOT is not available universally at all medical centers, and there is often considerable delay associat...

journal_title：Surgical infections

authors： Shaw JJ,Psoinos C,Emhoff TA,Shah SA,Santry HP

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The third most common healthcare-associated infection is surgical site infection (SSI), accounting for 14%-16% of infections. These SSIs are associated with high morbidity, numerous deaths, and greater cost. METHODS:A prospective study was conducted to assess the incidence of SSI in a single university hosp...

journal_title：Surgical infections

authors： Bogdanic B,Bosnjak Z,Budimir A,Augustin G,Milosevic M,Plecko V,Kalenic S,Fiolic Z,Vanek M

更新日期：2013-06-01 00:00:00

abstract：: Background: Within the United States, surgical site infections (SSIs) have now become the most common hospital-acquired infection and impact 2%-5% of all surgical patients. It is estimated that approximately 60% of SSIs could be prevented through improved adherence to pre-...

journal_title：Surgical infections

authors： Collins CR,Wick EC

更新日期：2019-10-01 00:00:00

abstract：: Background: This study was performed to investigate the combination of admission serum procalcitonin (PCT) and albumin (alb) concentrations as a diagnostic predictor for discriminating patients with nosocomial blood stream infection (BSI) among those with spontaneous intra...

journal_title：Surgical infections

authors： Deng S,Gao J,Zhao Z,Tian M,Li Y,Gong Y

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:We defined the contemporary conversion rate from laparoscopic appendectomy (LA) to open appendectomy and identified pre-operative factors associated with conversion. METHODS:Retrospective review of 941 consecutive LAs performed for suspected acute appendicitis in a single urban university hospital between 2...

journal_title：Surgical infections

authors： Wagner PL,Eachempati SR,Aronova A,Hydo LJ,Pieracci FM,Bartholdi M,Umunna BP,Shou J,Barie PS

更新日期：2011-08-01 00:00:00

abstract：: Background: Sarcopenia is a syndrome that can have negative consequences after gastric cancer (GC) surgery. This study aims to determine the effect of sarcopenia on surgical site infection (SSI) that develops after open GC surgery. Patients and Met...

journal_title：Surgical infections

authors： Olmez T,Gulmez S,Karakose E,Ofluoglu CB,Senger AS,Bozkurt H,Duman M,Polat E

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:The approach to perioperative antibiotic prophylaxis, bowel preparation, and postoperative routines in elective colorectal resections has changed over the last two decades. The aim of this national survey was to document the current methods of perioperative management of those patients scheduled for elective...

journal_title：Surgical infections

authors： Shpitz B,Reissman P,Rabau M,Ziv Y

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Chronic osteomyelitis associated with a stage IV decubitus ulcer is a challenging condition to manage, characterized by frequent relapses and need for long-term anti-microbial therapy. Although gram-positive cocci are the most common causes, fungal infections have been reported, usually in immunocompromised ...

journal_title：Surgical infections

authors： Jain NS,Horn CB,Coleoglou Centeno AA,Ilahi ON,Mazuski JE,Bocchichio GV,Punch LJ

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Vancomycin is used widely as empiric therapy for gram-positive organisms in patients with an intra-abdominal infection (IAI), even in those with no history of methicillin-resistant Staphylococcus aureus (MRSA) infection or colonization. Potential adverse effects of vancomycin include nephrotoxicity, increase...

journal_title：Surgical infections

authors： Hennessy SA,Shah PM,Guidry CA,Davies SW,Hranjec T,Sawyer RG

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:We aim to assess the patient factors and concomitant infectious outcomes associated with urinary tract infection (UTI) occurrence and the impact of UTI on length of stay (LOS), re-admission, and death in a colorectal surgical population. PATIENTS AND METHODS:National Surgical Quality Improvement Program Use...

journal_title：Surgical infections

authors： Armstrong JG,Li CH,Liao J,Byrn JC

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Gentamicin is used commonly as an empiric antibiotic prior to culture evidence in the treatment of ventilator-associated pneumonia (VAP) in surgical patients. METHODS:The published literature on the use of gentamicin for empiric therapy in VAP was reviewed and in combination with the author's personal exper...

journal_title：Surgical infections

authors： Byrnes M,Dorman R

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The designation "gram-positive bacillus" includes a variety of pleomorphic microorganisms, including diphtheroids, coryneform species, coccobacilli, and other small rods. Despite differing greatly in their virulence, sources, and even genus, these microscopically similar organisms are often difficult to diff...

journal_title：Surgical infections

authors： Clarke TM,Citron DM,Towfigh S

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Nocardia farcinica is a gram-positive, partially acid-fast, methenamine silver-positive aerobic actinomycete. Nocardia spp. are opportunistic pathogens, and N. farcinica is the least common species of clinical importance. METHODS:Review of the recent literature and description of a immunocompetent patient w...

journal_title：Surgical infections

authors： Budzik JM,Hosseini M,Mackinnon AC Jr,Taxy JB

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Although there are some commonalities between pediatric and adult sepsis, there are important differences in pathophysiology, clinical presentation, and therapeutic approaches. The recognition and diagnosis of sepsis is a significant challenge in pediatric patients as vital sign aberrations and examination f...

journal_title：Surgical infections

authors： Emr BM,Alcamo AM,Carcillo JA,Aneja RK,Mollen KP

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Deep sternal incisional surgical site infection is a serious and potentially life-threatening complication after open heart surgery. Although a rare post-operative complication, the rates of post-operative morbidity and mortality are greater in patients who develop a deep sternal incisional surgical site inf...

journal_title：Surgical infections

authors： Shih YJ,Chang SC,Wang CH,Dai NT,Chen SG,Chen TM,Tzeng YS

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Implant infection is a common clinical complication of abdominal hernia repair. Our objectives were to determine if acellular dermal matrix (ADM) grafts resisted Staphylococcus aureus infection better (as measured by ability to reduce or clear bacterial counts) than synthetic (polytetrafluoroethylene [PTFE])...

journal_title：Surgical infections

authors： Milburn ML,Holton LH,Chung TL,Li EN,Bochicchio GV,Goldberg NH,Silverman RP

更新日期：2008-08-01 00:00:00