Abstract：
:A high omega-6/omega-3 ratio, as is found in today's Western diets, promotes the pathogenesis of many chronic diseases, including cardiovascular disease. Increased dietary intake of linoleic acid (LA) leads to oxidation of low-density lipoprotein (LDL), platelet aggregation, and interferes with the incorporation of essential fatty acids (EFA) in cell membrane phopholipids. Both omega-6 and omega-3 fatty acids influence gene expression. Omega-3 fatty acids have strong anti-inflammatory effects, suppress interleukin 1 beta (IL-1 beta), tumor necrosis factor-alpha (TNF alpha) and interleukin-6 (IL-6), whereas omega-6 fatty acids tend to be pro-inflammatory. Because inflammation is at the base of many chronic diseases, including coronary heart disease, dietary intake of omega-3 fatty acids plays an important role in the manifestation of disease, particularly in persons with genetic variation, as for example in individuals with genetic variants at the 5-lipoxygenase (5-LO). Increased dietary arachidonic acid (AA) significantly enhances the apparent atherogenic effect of genotype, whereas increased dietary intake of omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) blunts this effect. The diet-gene interaction further suggests that dietary omega-6 fatty acids promote, whereas marine omega-3 fatty acids EPA and DHA inhibit leukotriene-mediated inflammation that leads to atherosclerosis in this subpopulation.
journal_name
Asia Pac J Clin Nutrjournal_title
Asia Pacific journal of clinical nutritionauthors
Simopoulos APsubject
Has Abstractpub_date
2008-01-01 00:00:00pages
131-4eissn
0964-7058issn
1440-6047journal_volume
17 Suppl 1pub_type
杂志文章,评审abstract：:The existence of 'intestinal failure' was proposed. This pathologic condition may occur in two distinct forms, ie short bowel syndrome marked by a gross reduction in functioning gut mass and impaired intestinal function (impairment of motility and extensive parenchymatous disorders). This has been newly recognized as ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:The effects of 4 weeks iron supplementation on haematological and immunological status were studied in 25 elite female soccer players aged 20-28 years. The subjects were randomized and assigned to one of the following two groups; subjects given 40 mg/day iron supplementation (S group) or those given placebo (C group)....
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2004-01-01 00:00:00
abstract：:To investigate the relationship between dietary intake of minerals and the risk of chronic obstructive pulmonary disease (COPD), a case-control study was conducted in central Japan. A total of 278 referred patients (244 men and 34 women) aged 50-75 years with COPD diagnosed within the past four years and 340 community...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:Our aim was to compare the effects of intravenous, enteral, and enteral plus intravenous supplemented glutamine on plasma transferrin, nitrogen balance, and creatinine/height index in septic patients with malnutrition. Blood and urine samples were collected for transferrin, urea and creatinine measurements. Samples, S...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.6133/apjcn.2014.23.1.11
更新日期：2014-01-01 00:00:00
abstract：:Hair mineral analysis using an X-ray fluorescence spectrometer as a method of estimating body fat percentage (BF%) was investigated. Body fat percentage of 24 healthy Japanese, aged 20-27 years, was measured using a hand-held impedance analyzer (BF%IMP). X-ray (Kα-ray) intensities of sulfur, chlorine, potassium, calci...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2013.22.2.14
更新日期：2013-01-01 00:00:00
abstract：:A micro level study on the haemoglobin status of 127 Munda (a tribe) and 174 Poundrakshatriya (Pod) (caste) women were conducted in the peri-urban area of Kolkata City, India. The two ethnic groups were selected in order to find out whether populations residing in the same habitat, with similar medical and health care...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:A nutritional status survey of Orang Asli (Aboriginal) adults in Lembah Belum, Grik, has been conducted involving a total of 138 subjects. Jahai (58.7%) was the main ethnic group as compared to that of Temiar (41.3%). Based on the Body Mass Index (BMI) characteristics, the majority (63.2%) of the respondents were norm...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:The epidemic of obesity is now a major public health concern in many parts of the world. Face-to-face tailored lifestyle modification therapy is one of the major approaches used for weight loss. However, the lack of time for multiple visits and the lack of resources for administering therapy hinder its implementation....
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2014.23.3.17
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Obesity is caused by excessive fat accumulation or abnormal fat distribution and has become one of the biggest health challenges worldwide. Considering the high thermogenic ability of brown fat tissue (BAT) and the plasticity of fat tissue, to induce the browning of white fat tissue (WAT), so ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.202012_29(4).0001
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Food systems are rapidly changing as world population grows, increasing urbanization occurs, consumer tastes and preferences change and differ in various countries and cultures, large scale food production increases, and food imports and exports grow in volume and value. Consumers in all countries have becom...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2007-01-01 00:00:00
abstract：:The present study was undertaken in two backward districts namely Phulbani and Sundargarh, of Orissa State, India, to study operational aspects of the distribution programme of iron fortified salt (IFS), and the extent of any overlap with the ongoing National Nutritional Anaemia Control Programme (NNACP) and possible ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：:Since low bone density is a risk for fracture, the relevance of bone densitometry as a basis for health care assessment needs to be elucidated. Most patients with fractures are in the lower two quartiles of bone density. Bone densitometry can be used to provide a quantitative estimate of fracture risk and a measurable...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:There is very limited published data on Tibetan dietary patterns and its association with nutrient intakes and socioeconomic factors. The aim of this study was to identify and describe the dietary patterns and the associations with nutrient intakes in rural Tibetan pregnant, lactating mothers....
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.012016.13
更新日期：2017-05-01 00:00:00
abstract：:While improvement in agricultural technology had enabled the production of abundant food, it has thus far failed to eliminate hunger. Malnutrition is expected to reach an all time high. Evidences have suggested that animal based diet has put immense pressure on the already fragile food system, contributing to problems...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2009-01-01 00:00:00
abstract：:In 2000, India revoked the ban on production and sale of non-iodised salt. We conducted a study in the north 24 Parganas district in the state of West Bengal to assess the prevalence of goitre, status of urinary iodine excretion (UIE) level and to estimate iodine content of salts at the household level. We surveyed 36...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:A number of imperatives require a re-think of science in general and of nutrition science in particular. Nutrition science has never been a body of knowledge in its own right and many other sciences have been nutritional in their orientation. At its best "nutrition science" has been integrative as well as reductionist...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
abstract：:Under-reporting of energy intake is a common problem in nutritional epidemiological studies. The aim of the present study was to determine the effect of under-reporting of energy intake on the estimates of nutrient intakes. In this cross-sectional study, 901 subjects aged >16 y were randomly selected from participants...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND & AIMS:Insulin sensitivity often decreases after surgery in spite of normal insulin secretion, and may worsen the outcome. This post-operative insulin resistance increases according to the magnitude of surgical invasion. However, supplementation of carbohydrates before surgery attenuates the post-operative i...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.6133/apjcn.2014.23.3.10
更新日期：2014-01-01 00:00:00
abstract：:Zinc nutriture was assessed in 6500 adults aged 35-64 years old in 65 mostly rural counties (two communes per county) in China on the basis of plasma zinc levels and dietary zinc intakes. In addition, the use of plasma albumin and red blood cell superoxide dismutase (SOD) for assessing zinc nutritional status was eval...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:In order to ascertain the coverage and to identify factors determining the success of an iodine deficiency disorders (IDD) control program in West Sumatra, Indonesia, a cross-sectional study among 495 school children aged 6-15 years in a subdistrict of an endemic goitre area was conducted. Coverage of iodine capsule d...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.1999.00040.x
更新日期：1999-03-01 00:00:00
abstract：:The modifying effects of garlic (Allium sativum Linn.) on hepatic lipid peroxidation and antioxidant status during 4-nitroquinoline 1-oxide (4NQO)-induced oral carcinogenesis were investigated in male Wistar rats. Enhanced lipid peroxidation in the liver of tumour-bearing animals was accompanied by significant decreas...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.2000.00153.x
更新日期：2000-06-01 00:00:00
abstract：:Observational studies suggest nut consumption is inversely associated with the incidence of cardiovascular disease and cancer. In addition to being rich in several vitamins and minerals, unsaturated fatty acids, and fiber, tree nuts and peanuts contain numerous phytochemicals that may contribute to promoting health an...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The present report summarized the best available evidence regarding consumption level and sources of free or added sugars in Indonesia. METHODS AND STUDY DESIGN:Information was extracted from food balance sheets, household expenditure surveys, nutrition surveys, published studies, unpublished...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.6133/apjcn.042017.07
更新日期：2018-01-01 00:00:00
abstract：:Macro mineral contents were estimated in commonly consumed green leafy vegetables in India, namely; Koyyathotakura and Peddathotakura (varieties of Amaranthus species); Erragogu and Tellagogu (variety of Hibiscus species); Gangabayalakura (Portulaca olereceo) and Palak (Spineces olerecea) at three different stages of ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:To evaluate how prenatal exposure to antioxidant vitamins and heavy metals affects subsequent development. Maternal serum and cord serum levels of antioxidant vitamins (A, E, and C) were determined. Full-state, performance, and verbal intelligence quotients (FSIQ, PIQ, and VIQ, respectively) of 97 children were assess...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2015.24.4.25
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The potential benefits of home enteral nutrition (HEN) and the effects of HEN on quality of life (QOL) after esophagectomy remain unclear. The aim was to investigate the effect of 3 months HEN on health related QOL and nutritional status of esophageal cancer patients who were preoperatively ma...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.032017.22
更新日期：2018-01-01 00:00:00
abstract：:To evaluate the antioxidative activity of the hydrolysates of ovalbumin, the antioxidative activities of the enzymatic extracts were evaluated using three different methodologies scavenging assays such as superoxide anion, hydroxyl radical, and inhibitory oxidation of linoleic acid in vitro, and the activities of SOD,...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:A total of twenty-three Australian Bass Strait scallops, Pecten fumatus processed by three different cooking methods: steam, battered and deep-fry, and pan-fry were analysed to determine the total lipid and health-benefiting n-3 PUFA contents. Fry process resulted in a significantly higher lipid content (p<0.05) with ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Mechanically ventilated patients often face progressive and rapid losses of body mass and muscle because of hypermetabolism and increased protein catabolism. To investigate the impact of adequate nutritional provision during the early phase of intensive care unit (ICU) admission on the clinica...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.032016.01
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The consumption of unhealthy snack and beverages can lead to childhood obesity, which has become a major concern globally. Television food advertisements may influence children's snack and beverages preferences. This article aims to explore children's snack and beverage consumption habits; exa...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.012017.04
更新日期：2017-01-01 00:00:00
