Abstract:
BACKGROUND:There is no available evidence from randomized trials that early detection of prostate cancer improves health outcomes, but the prostate-specific antigen (PSA) test is commonly used to screen men for prostate cancer. OBJECTIVE:The objective of the study is to see if screening with PSA decreases mortality from prostate cancer. DESIGN, SETTING, AND PARTICIPANTS:This is a case-control study using one-to-one matching on race, age, and time of availability of exposure to PSA screening. Decedents, 380, from New Jersey Vital Statistics 1997 to 2000 inclusive, 55-79 years of age at diagnosis were matched to living controls without metastatic prostate cancer. Medical records were obtained from all providers, and we abstracted information about PSA tests from 1989 to the time of diagnosis in each index case. MEASUREMENTS:Measurements consist of a comparison of screening (yes, no) between cases and controls. Measure of association was the odds ratio. RESULTS:Eligible cases were diagnosed each year from 1989 to 1999 with the median year being 1993. PSA screening was evident in 23.2-29.2% of cases and 21.8-26.1% of controls depending on the screening criteria. The unadjusted, matched odds ratio for dying of prostate cancer if ever screened was 1.09 (95% CI 0.76 to 1.60) for the most restrictive criteria and 1.19 (95% CI, 0.85 to 1.66) for the least restrictive. Adjustment for comorbidity and education level made no significant differences in these values. There were no significant interactions by age or race. CONCLUSIONS:PSA screening using an ever/never tabulation for tests from 1989 until 2000 did not protect New Jersey men from prostate cancer mortality.
journal_name
J Gen Intern Medjournal_title
Journal of general internal medicineauthors
Marcella SW,Rhoads GG,Carson JL,Merlino F,Wilcox Hdoi
10.1007/s11606-007-0479-7subject
Has Abstractpub_date
2008-03-01 00:00:00pages
248-53issue
3eissn
0884-8734issn
1525-1497journal_volume
23pub_type
杂志文章abstract:BACKGROUND:Global health measures represent an attractive option for researchers and clinicians seeking a brief snapshot of a patient's overall perspective on his or her health. Because scores on different global health measures are not comparable, comparative effectiveness research (CER) is challenging. OBJECTIVE:To ...
journal_title:Journal of general internal medicine
pub_type: 杂志文章
doi:10.1007/s11606-015-3453-9
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To determine whether echocardiography affects the decisions to use beta blockers or to recommend bacterial endocarditis prophylaxis in patients suspected of having mitral valve prolapse (MVP). DESIGN:Retrospective review of echocardiograms and clinical records. SETTING:Military tertiary care hospital. PATI...
journal_title:Journal of general internal medicine
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abstract:BACKGROUND:Domestic violence (DV) is prevalent across all racial and socioeconomic classes in the United States. Little is known about whether physicians differentially screen based on a patient's race or socioeconomic status (SES) or about resident physician screening attitudes and practices. OBJECTIVE:To assess the ...
journal_title:Journal of general internal medicine
pub_type: 杂志文章
doi:10.1111/j.1525-1497.2006.00494.x
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:To compare the prevalence of hot flashes and health education regarding menopause in African-American and white American women in the late reproductive years. DESIGN:Cross-sectional study. SETTING:Population-based sample recruited through random digit dialing. PARTICIPANTS:The sample was 436 women between ...
journal_title:Journal of general internal medicine
pub_type: 杂志文章
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journal_title:Journal of general internal medicine
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journal_title:Journal of general internal medicine
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更新日期:1996-12-01 00:00:00
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journal_title:Journal of general internal medicine
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更新日期:1995-12-01 00:00:00
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更新日期:2009-06-01 00:00:00
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journal_title:Journal of general internal medicine
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更新日期:2021-01-05 00:00:00
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更新日期:1998-07-01 00:00:00
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journal_title:Journal of general internal medicine
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更新日期:2013-07-01 00:00:00
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更新日期:2014-05-01 00:00:00