Abstract：
:Transfer and toxic effects of two cadmium (Cd) forms, inorganic (CdCl2 dosed rat food) or organic (contaminated snail-based rat food) were studied in Wistar rat. Cd concentrations in rat food were 0 and 2.5 microg Cd g(-1) for both inorganic and organic forms and a high concentration of 100 microg Cd g(-1) was also tested for the inorganic form. Rats were exposed for four weeks to contaminated food. Both forms of Cd were bioavailable to rats, with a percentage of transfer from food to rats of around 1% for all contaminated groups. Cd concentrations in rat tissues increased with increasing Cd concentrations in the food. Rats fed with organic form of Cd accumulated significantly more Cd in the main organ for Cd toxicity, the kidney, than those eating the inorganic form. Survival was not affected for any rat group but a decrease in growth and food consumption was observed for the inorganic form. As a defence system against Cd toxicity, rats increased their metallothionein (MT) synthesis at the highest Cd concentration in the target organs (kidney, liver and small intestine) and even did the same at low Cd concentrations (2.5 microg Cd g(-1)) in the kidney. At this low Cd concentration, MT induction was lower in the small intestine of rats ingesting organic Cd than those ingesting inorganic Cd. Bioavailability of organic and inorganic forms of Cd was similar, but subsequent Cd distribution within organs was different. This quantification of the trophic transfer of both inorganic and organic forms of a toxicant is a basis for a better assessment of the fate and effects of chemicals in food webs.
journal_name
Environ Intjournal_title
Environment internationalauthors
Hispard F,de Vaufleury A,Cosson RP,Devaux S,Scheifler R,Coeurdassier M,Gimbert F,Martin H,Richert L,Berthelot A,Badot PMdoi
10.1016/j.envint.2007.09.003subject
Has Abstractpub_date
2008-04-01 00:00:00pages
381-9issue
3eissn
0160-4120issn
1873-6750pii
S0160-4120(07)00169-9journal_volume
34pub_type
杂志文章abstract：:The exposome is a concept that encompasses the totality of internal and external environmental exposures, from conception onwards. Evaluation of the exposome, across the lifecourse represents a significant challenge, e.g., methods/technology may simply not exist to comprehensively assess all exposures, or they may not...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2018.10.041
更新日期：2018-12-01 00:00:00
abstract：:It has been shown that the exposure to airborne particulate matter is one of the most significant environmental risks people face. Since indoor environment is where people spend the majority of time, in order to protect against this risk, the origin of the particles needs to be understood: do they come from indoor, ou...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2017.07.025
更新日期：2017-11-01 00:00:00
abstract：:Treated wastewater (TWW) is increasingly used for agricultural irrigation, especially in arid and semi-arid regions. Carbamazepine is among the most frequently detected pharmaceuticals in TWW. Moreover, its uptake and accumulation have been demonstrated in crops irrigated with TWW. A previous controlled trial found th...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2020.105951
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:Epidemiological studies have linked air pollutant to adverse health effects even at low exposure levels, but limited evidence is available on its associations with gene expression levels. AIM:To investigate associations between air pollutants and gene expression levels. METHODS:We collected data from Brisb...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2020.105610
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Few studies have examined the risk of long-term exposure to source-specific airborne pollutants on incidence of cerebrovascular and cardiovascular events. OBJECTIVES:We aimed to estimate the effect of long-term exposure to source-specific air pollution and particulate matter (PM) components on incidence of ...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2020.105854
更新日期：2020-09-01 00:00:00
abstract：:Seaweed has a long-associated history of use as a supplemented livestock feed, providing nutrients and vitamins essential to maintaining animal health. Some species of seaweed, particularly the fucoids, are well-known accumulators of the metalloid arsenic (As). Arsenic toxicity to humans is well established even at lo...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2018.05.032
更新日期：2018-09-01 00:00:00
abstract：:This study investigated perfluoroalkyl acids (PFAAs) in edible parts of vegetables, soils, and irrigation water in greenhouse and open filed, for the first time, in Shouguang city, the largest vegetable production base in China, which is located nearby a fluorochemical industrial park (FIP). The bioaccumulation factor...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2019.105347
更新日期：2020-02-01 00:00:00
abstract：:Airborne microorganisms (AM), vital components of particulate matters (PM), are widespread in the atmosphere. Since some AM have pathogenicity, they can lead to a wide range of diseases in human and other organisms, meanwhile, some AM act as cloud condensation nuclei and ice nuclei which let them can affect the climat...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2018.01.007
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Ambient fine particulate matter (PM2.5) pollution is currently a serious environmental problem in China, but evidence of health effects with higher resolution and spatial coverage is insufficient. OBJECTIVE:This study aims to provide a better overall understanding of long-term mortality effects of PM2.5 pol...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2017.10.015
更新日期：2018-01-01 00:00:00
abstract：:Mercury (Hg) is a potentially harmful trace element in the environment and one of the World Health Organization's foremost chemicals of concern. The threat posed by Hg contaminated soils to humans is pervasive, with an estimated 86 Gg of anthropogenic Hg pollution accumulated in surface soils worldwide. This review cr...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2019.03.019
更新日期：2019-05-01 00:00:00
abstract：:Current practice of chemical risk assessment for consumer product ingredients still rarely exercises the aggregation of multi-source exposure. However, focusing on a single dominant source/pathway combination may lead to a significant underestimation of the risk for substances present in numerous consumer products, wh...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2015.03.006
更新日期：2015-06-01 00:00:00
abstract：:An association between serum concentrations of persistent organic pollutants (POPs), such as 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153), and risk of type 2 diabetes mellitus (T2DM) has been reported. Conditional on body mass index (BMI) and waist circumference (WC), a higher serum PCB-153 concentration may be a marke...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2018.12.036
更新日期：2019-04-01 00:00:00
abstract：:Since 2000 there has been an on-going industrial transition to replace long-chain perfluoroalkyl carboxylic acids(PFCAs), perfluoroalkane sulfonic acids (PFSAs) and their precursors. To date, information on these replacements including their chemical identities, however, has not been published or made easily accessibl...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2013.08.021
更新日期：2013-10-01 00:00:00
abstract：:Substance abuse during pregnancy is an important public health issue affecting the mother and the growing infant. Preterm labor, miscarriage, abruption and postpartum hemorrhage are obstetric complications which have been associated with women who are dependent on abused substances. Moreover, women are also at an incr...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2013.01.011
更新日期：2013-04-01 00:00:00
abstract：:It is well known that dissolved organic matter in soil solution may affect the toxicity or bioavailability of heavy metals to plants, but existing information on various organic substances is insufficient for treating problems with heavy metal-contaminated soils. To clarify how dissolved organic matter alters the toxi...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2004.10.017
更新日期：2005-05-01 00:00:00
abstract：:Workers in several industries are occupationally exposed to flame retardants. This study characterizes flame retardant exposure for nine industries through air and hand wipe measures for 105 workers. Specifically, we analyzed 24 analytes from three chemical classes: organophosphate flame retardants (OFRs), polybromina...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2019.105349
更新日期：2020-02-01 00:00:00
abstract：:There has been a substantial research focus on the presence of pesticides in flowers and the subsequent exposure to honeybees. Here we demonstrate for the first time that honeybees can also be exposed to pharmaceuticals, commonly present in wastewater. Residues of carbamazepine (an anti-epileptic drug) up to 371 ng/mL...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2019.105248
更新日期：2020-01-01 00:00:00
abstract：:Environmental metabonomics is the application of metabonomics to characterize the interactions of organisms with their environment. Metabolic profiling is an exciting addition to the armory of the epidemiologist for the discovery of new disease risk biomarkers and diagnostics. This work is a continuation of research s...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2014.03.015
更新日期：2014-07-01 00:00:00
abstract：:Lakes are one of the natural reservoirs of antibiotic resistance genes (ARGs) in environments. Long retention times in lakes potentially allow ARGs to persist and may create increased opportunities for the emergence of resistant pathogens. In this study, we investigated the prevalence, source and dissemination risk of...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2019.03.048
更新日期：2019-06-01 00:00:00
abstract：:Sediments used in this study were collected from different depths of eight sites in East China Sea in November 2002. The levels and distribution patterns of the selected organochlorine pesticides (OCPs=p,p'-DDT, o,p'-DDT, p,p'-DDE, p,p'-DDD, alpha-, beta-, gamma- and delta-HCH) in samples were investigated by the tech...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2005.05.027
更新日期：2005-08-01 00:00:00
abstract：:The discovery of antibiotics is considered one of the most significant scientific achievements of the 20th century, revolutionizing both human and veterinary medicine. However, antibiotics have been recently recognized as an emerging class of environmental contaminants since they have been massively administrated in h...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2016.06.025
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:Bisphenol A (BPA) is a widespread endocrine-disrupting chemical with estrogen like effects, which could interfere with the human reproductive system by disrupting the normal function of granulosa cells (GCs) leading to abnormal ovarian function. However, the mechanism of its toxicity on human GCs has not bee...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2020.106298
更新日期：2021-02-01 00:00:00
abstract：:Being persistent, toxic, and bio-accumulative, Mercury (Hg) seriously affects the environment and human health. Due to Hg's attribute of long-range environmental transport across national borders, especially through atmospheric transport, no country can fully protect its environment and human health with its own effor...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2014.10.023
更新日期：2015-02-01 00:00:00
abstract：:Understanding how microbial communities change with environmental degradation and restoration may offer new insights into the understudied ecology that connects humans, microbiota, and the natural world. Immunomodulatory microbial diversity and 'Old Friends' are thought to be supplemented from biodiverse natural envir...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2019.05.011
更新日期：2019-08-01 00:00:00
abstract：:Breast milk samples (n=74) from the general maternal population of Zhejiang province were analyzed for polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs). Samples were divided into urban and rural groups. Mean ∑PCDD/F, ∑PCB and ∑PBDE concent...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2011.04.004
更新日期：2012-07-01 00:00:00
abstract：:Limited data on the pollution status of spatially extensive water systems constrain health-risk assessments at basin-scales. Using a recipient measurement approach in a terminal water body, we show that agricultural and industrial pollutants in groundwater-surface water systems of the Aral Sea Drainage Basin (covering...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2010.11.006
更新日期：2011-02-01 00:00:00
abstract：:The role of the placenta was assessed by comparing the profiles of methylmercury (MeHg), inorganic mercury (I-Hg), lead (Pb), cadmium (Cd), selenium (Se), zinc (Zn), and copper (Cu) in freeze-dried chorionic tissue of the placenta and umbilical cord tissue. The significance of the placenta and cord tissue as predictor...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2013.08.007
更新日期：2013-10-01 00:00:00
abstract：:We have measured the concentrations of polychlorinated dibenzo-p-dioxins (PCDD/F), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDE) in 10 market baskets consisting of almost 4000 individual food samples representing 228 different food items, and also in the total diet basket. Lower bound con...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2004.03.002
更新日期：2004-09-01 00:00:00
abstract：:Multiple chemicals are emitted in residential accommodation. Aggregate Daily Doses (ADD) (ng/kg-bw/d) were estimated for 32 semivolatile organic compounds (SVOCs) of different chemical families that are frequently detected in French dwellings in both air and settled dust. Daily doses were determined using steady-state...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2017.08.024
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Studies investigating short-term exposure to ambient air pollution and heart rate variability (HRV) suggest that particulate matter (PM) exposure is associated with reductions in measures of HRV. Mitochondria are sensitive to PM exposure and may represent a biologically relevant underlying mechanism. However...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2018.11.028
更新日期：2019-02-01 00:00:00
