Metabolism of inorganic arsenic and non-cancerous health hazards associated with chronic exposure in humans.

Abstract:

:Humans can be exposed to arsenic from a variety of environmental, occupational and medicinal sources. Exposure from drinking water is the most common source nowadays. Inorganic arsenic is metabolized by two main biochemical reactions: reduction and oxidative methylation. Recent studies have confirmed a reactivation of the toxic effects of arsenic associated with such methylation process, because the methylated metabolites, especially the trivalent forms, are more toxic than the inorganic arsenicals. Chronic exposure to arsenic can cause a variety of cancerous and noncancerous health hazards in humans. The main non-cancerous health hazards include cardiovascular disease, skin lesions, neurological problems, diabetes mellitus and hypertension.

journal_name

J Environ Biol

authors

Tseng CH

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

349-57

issue

2 Suppl

eissn

0254-8704

issn

2394-0379

journal_volume

28

pub_type

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