Glutathione and associated enzymes in toxic cataractogenesis-selenite model.

Abstract:

:Glutathione, gamma-glutamyl cysteine synthetase (gamma -GCS) and glutathione reductase (GSH-R) activity were determined biochemically in the lens during various stages after subcutaneous administration of sodium selenite in multiple low dosages and single high dosages. The GSH concentration and gamma-GCS and GSH-R activity declined progressively after the selenite administration. The changes observed were discussed in relation to the possible role of selenite interaction with GSH and the enzymes.

journal_name

J Environ Biol

authors

Mathew JP,Joseph P,Thomas VC,Thomas I

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

733-8

issue

4

eissn

0254-8704

issn

2394-0379

journal_volume

27

pub_type

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