Use of weekly alendronate to treat osteoporosis in boys with muscular dystrophy.

Abstract:

:Three boys with muscular dystrophy with known osteoporosis were each treated for 1 yr with weekly alendronate and daily calcium and vitamin D. Measurements of lumbar spine and proximal femur using dual-energy x-ray absorptiometry were obtained at the initiation of the alendronate, at 6 mos, and at 1 yr. All three boys demonstrated increases in bone mineral density, with z scores improving from baseline to 1-yr follow-up. Improvements were observed at the lumbar spine, femoral neck, and greater trochanter. In this small case series, weekly oral alendronate for 1 yr plus daily vitamin D and calcium was effective in improving bone mineral density.

journal_name

Am J Phys Med Rehabil

authors

Apkon S,Coll J

doi

10.1097/PHM.0b013e3181583ddc

subject

Has Abstract

pub_date

2008-02-01 00:00:00

pages

139-43

issue

2

eissn

0894-9115

issn

1537-7385

journal_volume

87

pub_type

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