Abstract:
BACKGROUND:This study applied tissue Doppler imaging and color tissue Doppler imaging to study atrial function changes in patients with hypertrophic cardiomyopathy (HCM). The profile of the segmental atrial velocities and the strain rate were determined and compared with those of normal matched control subjects. METHODS:This study investigated 20 patients with HCM and 20 age-matched healthy control subjects. In a four-chamber apical view, tissue Doppler imaging was used to measure the lateral left and right atrial (LA and RA) and interatrial septal (IAS) wall systolic, early, and late diastolic velocities. Similarly, the atrial strain rate during ventricular systole (SR(S)) and the early (SR(E)) and late (SR(A)) diastolic phases in patients and control subjects were measured. The interventricular septal tissue Doppler-derived isovolumic relaxation time was calculated. RESULTS:Only the IAS annular and middle segments showed a significant reduction in the early diastolic velocity (mean, 4.01 +/- 2.2 vs 8.7 +/- 1.1, p = 0.001; 3.23 +/- 2 vs 6.01 +/- 1.9, p = 0.001, respectively) for the patients with HCM in comparison with the control subjects. Generally, the atrial strain rate was clearly reduced. The systolic strain rate (SR(S)) was significantly reduced in the LA wall in the annular (p = 0.007) and middle (p = 0.001) segments and in the IAS middle segment (p = 0.007). Similarly, there was a reduction of the early diastolic strain rate (SR(E)) in the LA annular (p = 0.001) and middle (p = 0.01) segments and in the IAS annular (p = 0.05) and middle (p = 0.001) segments, as well as in the RA annular segment (p = 0.02). The RA middle segments showed insignificant changes. CONCLUSION:Atrial function may be affected by HCM due to impairment of myocardial diastolic function. Strain rate imaging is reproducible, yields readily obtained parameters that provide unique data about global and longitudinal segmental atrial contraction, and can quantify the atrial dysfunction in patients with HCM.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Telagh R,Hui W,Abd El Rahman M,Berger F,Lange PE,Abdul-Khaliq Hdoi
10.1007/s00246-007-9112-0subject
Has Abstractpub_date
2008-03-01 00:00:00pages
301-8issue
2eissn
0172-0643issn
1432-1971journal_volume
29pub_type
杂志文章abstract::Many different types of potassium channels with various functions exist in pulmonary artery smooth muscle cells, contributing to many physiological actions and pathological conditions. The deep involvement of these channels in the onset and exacerbation of pulmonary arterial hypertension (PAH) also continues to be rev...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-016-1491-7
更新日期:2017-01-01 00:00:00
abstract::Catheter ablation in children requires placement of multiple large femoral venous sheaths and catheters. Magnetic resonance angiography (MRA) was used to evaluate the effect of indwelling lines on femoral venous blood flow. Between October 1993 and February 1994 a total of 17 patients scheduled for catheter ablation u...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900151
更新日期:1997-05-01 00:00:00
abstract::There has been substantial controversy regarding treatment of congenital heart defects in infants with trisomies 13 and 18. Most reports have focused on surgical outcomes versus expectant treatment, and rarely there has been an effort to consolidate existing evidence into a more coherent way to help clinicians with de...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-020-02444-6
更新日期:2020-10-01 00:00:00
abstract::Color-coded two-dimensional (2D) echocardiography confirmed the presence of severe congenital mitral regurgitation in an 8-month-old infant. Intraoperative inspection revealed an isolated perforation in the anterior leaflet. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02239570
更新日期:1990-04-01 00:00:00
abstract::Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a heritable cardiomyopathy characterized by fibro-fatty replacement of right ventricular myocardium. Diagnostic criteria, established in 1994 and modified in 2010, are based on predominately adult manifestations of ARVC/D. The goal of this paper is ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-015-1327-x
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:In 2017, the AHA published revised guidelines for the diagnosis of Kawasaki disease (KD). In the absence of compelling data supporting or refuting the utility of lack of tapering (LT) and perivascular brightness (PB), expert panel consensus removed LT and PB from consideration. We hypothesize that LT and PB ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-018-1971-z
更新日期:2019-01-01 00:00:00
abstract::In adult heart failure (HF) patients, a higher ventricular arterial (VA) coupling ratio measured non-invasively is associated with worse HF prognosis and response to treatment. There are no data regarding the relationship of VA coupling to outcome in pediatric dilated cardiomyopathy (DCM) patients. We investigated the...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-018-2021-6
更新日期:2019-02-01 00:00:00
abstract::With the advent of cardiac magnetic resonance imaging and high-resolution echocardiography, cardiac catheterization is unnecessary in clinical protocols in the "routine" single ventricle patient. Catheterization adds little to clinical care in these cases, and there are significant risks and costs associated with it. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-004-0960-6
更新日期:2005-03-01 00:00:00
abstract::A reduced exercise capacity is a common finding in adult congenital heart disease and is associated with cardiovascular morbidity and mortality. However, data on exercise capacity in patients after repair of coarctation of the aorta (CoA) are scarce. Furthermore, a high rate of exercise-induced hypertension has been d...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02173-5
更新日期:2019-10-01 00:00:00
abstract::Unilateral absence of a pulmonary artery is a rare anomaly. Patients may present with hemoptysis, recurrent respiratory infections, pulmonary hypertension, or congestive heart failure. This report describes the case of a missing right pulmonary artery associated with anomalous left pulmonary venous connection not prev...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-011-0110-x
更新日期:2012-01-01 00:00:00
abstract::In our institute, 1100 patients with a history of Kawasaki disease have been catheterized for selective coronary arteriography. Their age at examination ranged from four months to 13 years. Coronary artery lesions (CAL) were found in 262 patients. As far as the type of the CAL was concerned, occlusion was noted in 20 ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02315475
更新日期:1986-01-01 00:00:00
abstract::A 6-year-old girl with type 3 long QT syndrome was safely and successfully implanted with an implantable cardioverter-defibrillator (ICD) system. Prior to implantation, she had experienced uncontrollable life-threatening arrhythmia in spite of high-dose administration of mexiletine. An ICD coil lead for transvenous us...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-011-0065-y
更新日期:2011-10-01 00:00:00
abstract::Subtotal cor triatriatum sinister (partially divided left atrium) is characterized by a membrane dividing the left atrium into two portions: a dorsal accessory proximal chamber that receives part of the pulmonary venous return and a small restrictive defect in the membrane that obstructs blood flow from the accessory ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-008-9205-4
更新日期:2008-07-01 00:00:00
abstract::Sinus node disease is a problem encountered in patients after the Mustard surgery, requiring a pacemaker implantation. The knowledge of the complexity anatomy is crucial because of the possible challenges associated with this procedure. We report a case of a 24-year-old woman presented with symptomatic bradycardia, in...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-015-1155-z
更新日期:2015-08-01 00:00:00
abstract::Paroxysmal non-reentrant supraventricular tachycardia due to double ventricular response through antegrade dual atrioventricular nodal pathways by a single atrial excitation has been reported in limited adult cases but not in pediatric patients with structurally normal hearts or with congenital heart defects. We repor...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0326-4
更新日期:2013-03-01 00:00:00
abstract::The importance of myocardial bridging of a coronary artery in the setting of hypertrophic cardiomyopathy is controversial, although we have previously reported an association with myocardial ischemia and sudden death in children. We report five symptomatic children in whom symptoms or evidence of myocardial ischemia r...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-003-0576-2
更新日期:2004-07-01 00:00:00
abstract::The timing of pulmonary valve replacement (PVR) in asymptomatic patients with repaired tetralogy of Fallot (TOF) is typically based on cardiac magnetic resonance imaging-derived ventricular volume measurements. Current criteria do not account for sex-based differences in chamber size. The purpose of this study was to ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02181-5
更新日期:2019-10-01 00:00:00
abstract::Venous correction for complete transposition with intact ventricular septum remains the preferred surgical option in most centers (Mustard or Senning procedures). The long-term function of the morphologically right ventricle and tricuspid valve, which continue to sustain the systemic circulation thereafter, remains a ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::Global ventricular response to exercise may be useful in follow-up of patients with residual right outflow tract lesions after congenital heart disease repair. In this context, impedance cardiography is considered accurate for stroke volume (SV) measurement during exercise testing, however, to date, only partial asses...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-017-1725-3
更新日期:2018-01-01 00:00:00
abstract::In this report, we describe a case of coarctation of the aorta, congenital aortic stenosis with bicuspid valve, and supravalvar aortic stenosis with left coronary artery ostial stenosis. The child underwent staged treatment using a hybrid approach employing both surgical and interventional cardiology methods. A single...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002460010164
更新日期:2001-01-01 00:00:00
abstract::The objective of this investigation was to compare how two modes of positive pressure ventilation affect cardiac output, airway pressures, oxygenation, and carbon dioxide removal in children with congenital heart disease in the immediate postoperative period. The investigation used a one group pretest-post-test study ...
journal_title:Pediatric cardiology
pub_type: 临床试验,杂志文章
doi:10.1007/s002460010210
更新日期:2001-05-01 00:00:00
abstract::In 2014, our hospital introduced inhaled nitric oxide (iNO) therapy combined with high-flow nasal cannula (HFNC) oxygen therapy after extubation following the Fontan procedure in patients with unstable hemodynamics. We report the benefits of HFNC-iNO therapy in these patients. This was a single-center, retrospective r...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02122-2
更新日期:2019-06-01 00:00:00
abstract::An aneurysm of the fossa ovalis was identified at autopsy in 17 infants. In each case the aneurysm of the fossa ovalis was considered to have resulted from excessive elevation of pressure in that atrium contralateral to the side into which the aneurysm bulged. The aneurysms were divided into two types: intrinsic (thre...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02282740
更新日期:1985-01-01 00:00:00
abstract::Beta-blocker therapy is one of the principal therapies for congenital long-QT syndrome (LQTS). However, breakthrough cardiac events occur while being treated with beta-blockers. We sought to determine the frequency of and clinical correlates underlying beta-blocker therapy failures in genotyped, symptomatic LQTS proba...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-003-0567-3
更新日期:2004-09-01 00:00:00
abstract::This study aimed to assess the impact of integrating a simulation-based education module into an extracorporeal membrane oxygenation (ECMO) curriculum on novice learners and to test the duration of time that skills obtained during this training exercise were retained. The authors hypothesized that multidisciplinary, s...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0490-6
更新日期:2013-03-01 00:00:00
abstract::Various echocardiographic parameters are determined in the assessment and evaluation of a patent ductus arteriosus. In isolation, many of these parameters have a low sensitivity and specificity for ductal hemodynamic significance compared with ductal size. This study aimed to correlate various echocardiographic parame...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0640-5
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVES:The aim of this article is to examine the frequency, timing of formation of aneurysm of the ventricular membranous septum (AVMS), and prognosis in patients with a perimembranous ventricular septal defect (VSD). PATIENTS:One hundred forty-eight patients were diagnosed with a perimembranous VSD within 90 days...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-003-0572-6
更新日期:2004-07-01 00:00:00
abstract::This study aimed to clarify the characteristics of pulmonary arterial resistance (Rp)-compliance (Cp) coupling in individuals with Down syndrome (DS), who have increased risks of pulmonary arterial hypertension (PAH). We performed cardiac catheterization before and after corrective surgery in 85 DS infants and 85 cont...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02080-9
更新日期:2019-04-01 00:00:00
abstract::This paper reviews the initial experience of radical correction of truncus arteriosus in the Soviet Union. The anatomy, hemodynamics, diagnosis and surgical technique are described in detail. Five patients were operated on; three survived. The two deaths in this series were due to mistakes in evaluating the indication...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02424960
更新日期:1984-04-01 00:00:00
abstract::Controversy exists as to whether a hemodynamically significant left-to-right shunt due to a patent ductus arteriosus (PDA) affects ventricular contractility. Load-dependent indices such as ejection fraction and shortening fraction have traditionally been used to assess contractility, but the relationship between the r...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-003-0452-0
更新日期:2004-03-01 00:00:00