Abstract:
:Few studies have investigated the presence of dyslipidaemia in hypertensive individuals. In addition, few data exist on the concurrent treatment of both conditions for the prevention of cardiovascular disease (CVD). This retrospective cohort study examined treatment patterns for hypertension and dyslipidaemia among hypertensive patients in UK primary care. We defined a population of patients aged > or =40 years from the UK General Practice Research Database. Hypertensive individuals with > or =3 additional cardiovascular risk factors (ARFs) were compared with a cohort comprising hypertensive patients with < or =2 ARFs. We analysed the prevalence of risk factors and the prevalence and incidence of treatment for hypertension, dyslipidaemia and for both conditions between January 1997 and December 2001. A total of 117 840 hypertensive patients were identified (23 655 with > or =3 ARFs, 94 185 with < or =2 ARFs) in 1997; in 2001, the number diagnosed as hypertensive was 133 683 (40 248 > or =3 ARFs, 93 435 < or =2 ARFs). The prevalence of antihypertensive treatment in the hypertensive patients with > or =3 ARFs increased during the study. In 2001, approximately one-third of hypertensive patients with > or =3 ARFs were not receiving antihypertensives. Among those patients who received such treatment, the majority received > or =2 separate agents in accordance with current guidelines. Treatment for concurrent hypertension and dyslipidaemia was initiated in <8% of patients with hypertension and > or =3 ARFs in each year. These findings demonstrate the under-recognition/undertreatment of cardiovascular risk factors in UK primary care among patients at risk of CVD.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
MacDonald TM,Morant SV,Mozaffari Edoi
10.1038/sj.jhh.1002249subject
Has Abstractpub_date
2007-12-01 00:00:00pages
925-33issue
12eissn
0950-9240issn
1476-5527pii
1002249journal_volume
21pub_type
杂志文章,多中心研究abstract::The aim of this study was to investigate the influence of ambient temperature on blood pressure (BP). BP measurements were taken in 20 normotensive volunteers who stayed in Greenland for a 6-week period. Measurements of systolic (SBP), diastolic (DBP) and heart rate (HR) were taken before (3 sessions), during (7-8 ses...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001134
更新日期:2001-02-01 00:00:00
abstract::The aim of this study was to describe the pattern of blood pressure (BP) distribution in a multiethnic primary care practice in relation to sociodemographic characteristics, lifestyle and risk factors. Another aim was to analyse the quality of diagnosis and effectiveness of hypertension (HT) treatment. In all, 470 adu...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001902
更新日期:2005-10-01 00:00:00
abstract::An evaluation of the 'Accutracker', a new lightweight ambulatory blood pressure monitor, has been carried out in 14 subjects. Using a cross-over study design, BP readings obtained by the monitor were compared with BP measurements carried out in the opposite arm by a random zero sphygmomanometer. Both the systolic and ...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1989-12-01 00:00:00
abstract::This meta-analysis attempted to derive pooled estimates for the putative association between echocardiographic or electrocardiographic left ventricular hypertrophy and the deletion/insertion (D/I) polymorphism of the angiotensin-I converting enzyme. Case-control studies were combined, using the Mantel and Haenszel app...
journal_title:Journal of human hypertension
pub_type: 杂志文章,meta分析
doi:10.1038/sj.jhh.1001055
更新日期:2000-07-01 00:00:00
abstract::Gender-specific determinants of blood pressure (BP) values and control have not been the focus of clinical hypertension research. The purpose of this analysis was to identify gender-specific and multi-level (physician and patient) determinants of BP values and predictors of uncontrolled BP. We completed a subgroup ana...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1038/jhh.2010.71
更新日期:2011-06-01 00:00:00
abstract::For nearly two decades, the National High Blood Pressure Education Programme has administered a programme of public, patient, and professional education in an effort to reduce uncontrolled hypertension, an important public health problem in the USA. A broad network has been established and many partners have joined fo...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:
更新日期:1992-12-01 00:00:00
abstract::Large differences exist within populations in the dietary intake of nutrients between men and women and these differences are still largely unknown. Using data obtained from the Intersalt study and from other relevant epidemiological studies, the sex ratio of the 24 h urinary excretion of different cations was obtaine...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1038/sj.jhh.1001784
更新日期:2005-02-01 00:00:00
abstract::We investigated whether inappropriately high left ventricular (LV) mass, defined as observed LV mass exceeding the level of individual LV mass predicted from gender, height, and stroke work, may be associated with an imbalance between growth-promoting and growth-inhibitory factors and/or structural vascular changes. I...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001720
更新日期:2004-06-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1038/jhh.2014.27
更新日期:2015-01-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1038/sj.jhh.1001744
更新日期:2004-11-01 00:00:00
abstract::Low-dose diuretics are recommended for the initial choice of antihypertensive therapy in the 7th US Joint National Committee report and are accepted as an appropriate choice among other classes of drugs in the 2003 European Society of Hypertension guidelines. The rationales for the use of low-dose diuretics include th...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/sj.jhh.1001798
更新日期:2004-12-01 00:00:00
abstract::An association of obesity and hypertension is well recognised and there is a direct positive relationship between body weight or body mass index (BMI) and blood pressure (BP), although the mechanisms responsible for weight-related increases of BP are still unknown. Obesity does appear to be an independent risk factor ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Left ventricular hypertrophy (LVH) is a powerful cardiovascular risk factor and has previously been related to endothelium-dependent vasodilation (EDV) in hypertensive patients. In the Prospective Investigation of the Vasculature in Uppsala Seniors study, different techniques to evaluate EDV in different types of vess...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2008.61
更新日期:2008-11-01 00:00:00
abstract::Primary aldosteronism (PA), the most common cause of secondary hypertension, is a well-recognized condition that can lead to cardiovascular and renal complications. PA is frequently left undiagnosed and untreated, leading to aldosterone-specific morbidity and mortality. In this review we highlight the evidence linking...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/s41371-019-0294-8
更新日期:2020-01-01 00:00:00
abstract::For the epidemiologist, the development of any new therapy or strategy must respond to the following three questions: does a need exist? Is there a new way of meeting that need? Can a valid assessment be made of the efficacy of the new therapy? New antihypertensive treatments or strategies are needed, even in 1994: in...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-01 00:00:00
abstract::In patients with severe hypertension, chronic heart failure or a history of stroke, the lower limit of autoregulation of cerebral blood flow (CBF) is shifted to higher levels of blood pressure (BP) than those observed in healthy subjects. The aim of pharmacotherapy for hypertensive patients with an impaired autoregula...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001735
更新日期:2004-10-01 00:00:00
abstract::There are complications in diagnosing hypertension in children and adolescents due to variation of blood pressure (BP) values to age, gender and height. This study was aimed at assessing whether the performance of BP-to-height ratio (BPHR) can be an effective tool for screening prehypertension and hypertension in Elli...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2017.25
更新日期:2017-09-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章,随机对照试验
doi:10.1038/jhh.2009.4
更新日期:2009-09-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-018-0059-9
更新日期:2018-06-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-020-0337-1
更新日期:2020-04-29 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001171
更新日期:2001-04-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1038/sj.jhh.1002220
更新日期:2007-10-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2017.65
更新日期:2017-12-01 00:00:00
abstract::Disturbed sympathetic and also parasympathetic activity of the autonomic nervous system points to pathological alterations in the cardiovascular system. Untreated hypertensive subjects were examined with respect to the question of whether an increase in sympathetic activity necessarily goes along with a reduction in p...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001671
更新日期:2004-05-01 00:00:00
abstract::Diabetes mellitus (DM)-linked metabolic alterations and hypertension concomitantly accelerate or precipitate cerebrovascular and coronary heart disease, nephropathy, retinopathy and widespread macroangiopathy, thereby conferring to diabetic patients a very high risk of morbidity, disability and early death. Therefore,...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:
更新日期:1992-12-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-019-0288-6
更新日期:2020-09-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-019-0183-1
更新日期:2019-05-01 00:00:00
abstract::Obstructive sleep apnoea (OSA) and hypertension commonly coexist. Observational studies indicate that untreated OSA is strongly associated with an increased risk of prevalent hypertension, whereas prospective studies of normotensive cohorts suggest that OSA may increase the risk of incident hypertension. Randomized ev...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/jhh.2011.47
更新日期:2012-05-01 00:00:00