Abstract：
:The development of a supportive vasculature is essential for tumor progression. In a mouse model of breast cancer, we found that tumor-associated macrophages that are recruited to the tumor just before malignant conversion are essential for the angiogenic switch. These findings establish a causal linkage to explain well-documented clinical correlations between macrophages, microvessel density, and poor prognosis in breast tumors.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Lin EY,Pollard JWdoi
10.1158/0008-5472.CAN-07-0912subject
Has Abstractpub_date
2007-06-01 00:00:00pages
5064-6issue
11eissn
0008-5472issn
1538-7445pii
67/11/5064journal_volume
67pub_type
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