Abstract:
:Impaired retrieval of conceptual knowledge for actions has been associated with lesions of left premotor, left parietal, and left middle temporal areas [Tranel, D., Kemmerer, D., Adolphs, R., Damasio, H., & Damasio, A. R. Neural correlates of conceptual knowledge for actions. Cognitive Neuropsychology, 409-432, 2003]. Here we aimed at characterizing the differential contribution of these areas to the retrieval of conceptual knowledge about actions. During functional magnetic resonance imaging (fMRI), different categories of pictograms (whole-body actions, manipulable and nonmanipulable objects) were presented to healthy subjects. fMRI data were analyzed using SPM2. A conjunction analysis of the neural activations elicited by all pictograms revealed ( p<.05, corrected) a bilateral inferior occipito-temporal neural network with strong activations in the right and left fusiform gyri. Action pictograms contrasted to object pictograms showed differential activation of area MT+, the inferior and superior parietal cortex, and the premotor cortex bilaterally. An analysis of psychophysiological interactions identified contribution-dependent changes in the neural responses when pictograms triggered the retrieval of conceptual action knowledge: Processing of action pictograms specifically enhanced the neural interaction between the right and left fusiform gyri, the right and left middle temporal cortices (MT+), and the left superior and inferior parietal cortex. These results complement and extend previous neuropsychological and neuroimaging studies by showing that knowledge about action concepts results from an increased coupling between areas concerned with semantic processing (fusiform gyrus), movement perception (MT+), and temporospatial movement control (left parietal cortex).
journal_name
J Cogn Neuroscijournal_title
Journal of cognitive neuroscienceauthors
Assmus A,Giessing C,Weiss PH,Fink GRdoi
10.1162/jocn.2007.19.6.1004subject
Has Abstractpub_date
2007-06-01 00:00:00pages
1004-12issue
6eissn
0898-929Xissn
1530-8898journal_volume
19pub_type
杂志文章abstract::A task that has been intensively studied at the neural level is f lutter discrimination. I argue that f lutter discrimination entails a combination of a temporal assignment problem and a quantity comparison problem, and propose a neural network model of how these problems are solved. The network combines unsupervised ...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2007.19.3.409
更新日期:2007-03-01 00:00:00
abstract::Response selection is the mental process of choosing representations for appropriate motor behaviors given particular environmental stimuli and one's current task situation and goals. Many cognitive theories of response selection postulate a unitary process. That is, one central response-selection mechanism chooses ap...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/089892903322598085
更新日期:2003-11-15 00:00:00
abstract::Abstract Three patients with semantic dementia, involving progressive deterioration of semantic memory, performed immediate serial recall of short sequences of familiar words. On the basis of their performance in other tasks of word comprehension and production, the stimuli were selected individually for each patient ...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.1994.6.1.57
更新日期:1994-01-01 00:00:00
abstract::Animals and humans learn statistical regularities that are embedded in sequences of stimuli. The neural mechanisms of such statistical learning are still poorly understood. Previous work in macaque inferior temporal (IT) cortex demonstrated suppressed spiking activity to visual images of a sequence in which the stimul...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_01135
更新日期:2017-08-01 00:00:00
abstract::We employed a parametric version of the comparison Stroop paradigm to investigate the processing of numerical magnitude and physical size under task-relevant and -irrelevant conditions to investigate two theoretical issues: (1) What is the neural fate of task-irrelevant information? (2) What is the neural basis of the...
journal_title:Journal of cognitive neuroscience
pub_type: 临床试验,杂志文章
doi:10.1162/jocn.2006.18.12.2049
更新日期:2006-12-01 00:00:00
abstract::Prosopagnosia is the neuropathological inability to recognize familiar people by their faces. It can occur in isolation or can coincide with recognition deficits for other nonface objects. Often, patients whose prosopagnosia is accompanied by object recognition difficulties have more trouble identifying certain catego...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/089892998562799
更新日期:1998-05-01 00:00:00
abstract::We investigated localization performance of simple targets in patient TN, who suffered bilateral damage of his primary visual cortex and shows complete cortical blindness. Using a two-alternative forced-choice paradigm, TN was asked to guess the position of left-right targets with goal-directed and discrete manual res...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_00404
更新日期:2013-10-01 00:00:00
abstract::In a previously conducted randomized placebo-controlled trial, we were able to demonstrate significant visual field enlargement induced by restitution therapy in patients with cerebral lesions [Kasten, E., Wuest, S., Behrens-Bamann, W., & Sabel, B. A. (1998c). Computer-based training for the treatment of partial blind...
journal_title:Journal of cognitive neuroscience
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1162/08989290051137530
更新日期:2000-11-01 00:00:00
abstract::It is not clear how salient distractors affect visual processing. The debate concerning the issue of whether irrelevant salient items capture spatial attention [e.g., Theeuwes, J., Atchley, P., & Kramer, A. F. On the time course of top-down and bottom-up control of visual attention. In S. Monsell & J. Driver (Eds.), A...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2009.21390
更新日期:2011-03-01 00:00:00
abstract::Behavioral studies indicate that spatial and object working memory are computed by dissociable subsystems. We investigated the neural bases of this dissociation with a whole-brain fMRI design and analysis technique that permitted direct assessment of delay-period activity, uncontaminated by other components of the tri...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/089892999563652
更新日期:1999-11-01 00:00:00
abstract::Most contemporary theories of semantic memory assume that concepts are formed from the distillation of information arising in distinct sensory and verbal modalities. The neural basis of this distillation or convergence of information was the focus of this study. Specifically, we explored two commonly posed hypotheses:...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_00244
更新日期:2012-08-01 00:00:00
abstract::Many behavioral tasks require goal-directed actions to obtain delayed reward. The prefrontal cortex appears to mediate many aspects of goal-directed decision making. This article presents a model of prefrontal cortex function emphasizing the influence of goal-related activity on the choice of the next motor output. Th...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/0898929054475190
更新日期:2005-07-01 00:00:00
abstract::Recent computational modeling and behavioral work indicate that age-related declines in the ability to represent task context may contribute to disruptions of working memory and selective attention in older adults. However, it is unclear whether age-related declines in context processing arise from a disruption of the...
journal_title:Journal of cognitive neuroscience
pub_type: 临床试验,杂志文章
doi:10.1162/089892904322755593
更新日期:2004-01-01 00:00:00
abstract::Numerical format describes the way magnitude is conveyed, for example, as a digit ("3") or Roman numeral ("III"). In the field of numerical cognition, there is an ongoing debate of whether magnitude representation is independent of numerical format. Here, we examine the time course of magnitude processing when using d...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_01257
更新日期:2018-07-01 00:00:00
abstract::Current computational and neuroscientific models of decision-making posit a discrete, serial processing distinction between upstream decisional stages and downstream processes of motor-response implementation. We investigated this framework in the context of two-alternative forced-choice tasks on linguistic stimuli, w...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_01606
更新日期:2020-11-01 00:00:00
abstract::Tactile-visual links in spatial attention were examined by presenting spatially nonpredictive tactile cues to the left or right hand, shortly prior to visual targets in the left or right hemifield. To examine the spatial coordinates of any crossmodal links, different postures were examined. The hands were either uncro...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/08989290152001899
更新日期:2001-05-15 00:00:00
abstract::The ability to generate and process semantic relations is central to many aspects of human cognition. Theorists have long debated whether such relations are coarsely coded as links in a semantic network or finely coded as distributed patterns over some core set of abstract relations. The form and content of the concep...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_01620
更新日期:2020-08-07 00:00:00
abstract::The occipito-temporal cortex is strongly implicated in carrying out the high-level computations associated with vision. In human neuroimaging studies, focal regions are consistently found within this broad region that respond strongly and selectively to faces, bodies, or objects. A notable feature of these selective r...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章,评审
doi:10.1162/jocn_a_00091
更新日期:2011-12-01 00:00:00
abstract::The solution of a problem left unresolved in the evening can sometimes pop into mind as a sudden insight after a night of sleep in the following morning. Although favorable effects of sleep on insightful behavior have been experimentally confirmed, the neural mechanisms determining this delayed insight remain unknown....
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2010.21550
更新日期:2011-08-01 00:00:00
abstract::Prosopagnosic patients appear to be impaired at recognizing faces. However, recent evidence for "covert recognition" in prosopagnosia has been taken to suggest that the impairment is not in face recognition per se, but rather in conscious access to face recognition. The most widely used test for covert recognition of ...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.1992.4.2.150
更新日期:1992-04-01 00:00:00
abstract::The ability to control how we process information by remembering that which is important and forgetting that which is irrelevant is essential to maintain accurate, up-to-date memories. As such, memory success is predicated on both successful intentional encoding and successful intentional forgetting. The current study...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_00310
更新日期:2013-02-01 00:00:00
abstract::Two patients (TC and SS) with lesions that included the hippocampal regions (predominantly on the left side) were severely impaired in their recall of simple, verbally stated facts. However, both patients remembered spatial information that was temporally associated with semantic information. Specifically, TC and SS c...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2007.19.11.1888
更新日期:2007-11-01 00:00:00
abstract::Recent fMRI studies have found that distinct neural systems may mediate perceptual category learning under implicit and explicit learning conditions. In these previous studies, however, different stimulus-encoding processes may have been associated with implicit versus explicit learning. The present design was aimed a...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2010.21538
更新日期:2011-07-01 00:00:00
abstract::Prospective memory (PM) refers to the cognitive processes associated with remembering to perform an intended action after a delay. Varying the salience of PM cues while keeping the intended response constant, we investigated the extent to which participants relied on strategic monitoring, through sustained, top-down c...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_01604
更新日期:2020-10-01 00:00:00
abstract::The role of the left and right hemisphere was examined during semantic priming by antonyms, remote associates, and unrelated words. Targets presented directly to the left hemisphere showed an early facilitation and a late developing inhibition, while targets presented directly to the right hemisphere showed a late dev...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.1991.3.4.313
更新日期:1991-10-01 00:00:00
abstract::Dynamically adjusting the right amount of goal shielding to varying situational demands is associated with the flexibility of cognitive control, typically linked with pFC functioning. Although stress hormones are found to also bind to prefrontal receptors, the link between stress and cognitive control remains elusive....
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_00024
更新日期:2011-11-01 00:00:00
abstract::We examined the relation between neural activity reflecting early face perception processes and automatic and controlled responses to race. Participants completed a sequential evaluative priming task, in which two-tone images of Black faces, White faces, and cars appeared as primes, followed by target words categorize...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_00014
更新日期:2011-10-01 00:00:00
abstract::In primates, different vocalizations are produced, at least in part, by making different facial expressions. Not surprisingly, humans, apes, and monkeys all recognize the correspondence between vocalizations and the facial postures associated with them. However, one major dissimilarity between monkey vocalizations and...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章,评审
doi:10.1162/jocn_a_00575
更新日期:2014-06-01 00:00:00
abstract::Audiovisual perception and imitation are essential for musical learning and skill acquisition. We compared professional pianists to musically naive controls with fMRI while observing piano playing finger-hand movements and serial finger-thumb opposition movements both with and without synchronous piano sound. Pianists...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/0898929053124893
更新日期:2005-02-01 00:00:00
abstract::Previous research has shown that attention to a specific location on a uniform visual object spreads throughout the entire object. Here we demonstrate that, similar to the visual system, spatial attention in touch can be object guided. We measured event-related brain potentials to tactile stimuli arising from objects ...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2009.21265
更新日期:2010-05-01 00:00:00