Abstract:
:We report seven cases of infective endocarditis caused by USA300 methicillin-resistant Staphylococcus aureus (MRSA) at an urban, tertiary care, academic institution. Five strains were community associated and two were healthcare associated. All patients were injection drug users. Staphylococcus aureus isolates were characterised as USA300-type MRSA using pulsed-field gel electrophoresis. Five cases were right-sided endocarditis and two cases were left-sided. The mean length of in-hospital antimicrobial therapy was 23 days and the mean length of total antibiotic therapy was 55 days. Complications included heart failure resulting in valve replacement in one patient as well as death in that patient. As USA300 strains of MRSA continue to increase in prevalence, clinicians must be aware of the increasing spectrum of illness in considering management and prevention strategies.
journal_name
Int J Antimicrob Agentsjournal_title
International journal of antimicrobial agentsauthors
Haque NZ,Davis SL,Manierski CL,Vager D,Donabedian SM,Perri MB,Sabbagh R,Cheema F,Zervos MJdoi
10.1016/j.ijantimicag.2007.02.007subject
Has Abstractpub_date
2007-07-01 00:00:00pages
72-7issue
1eissn
0924-8579issn
1872-7913pii
S0924-8579(07)00109-4journal_volume
30pub_type
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