Abstract:
:As with other addictions, human alcoholism is characterised as a chronically relapsing condition. Consequently, the therapeutic goal is the development of clinically effective, safe drugs that promote high adherence rates and prevent relapse. These products can then be used in conjunction with psychosocial approaches. In this review, preclinical studies are highlighted that indicate the mechanism of action of currently used anti-craving medications or demonstrate the potential of novel pharmacological agents for the treatment of alcohol use disorders. While current pharmacological strategies are far from ideal, there are a number of candidate molecules that may ultimately be developed into therapeutic agents. In addition, prescribing clinicians should also consider strategies such as combinations of various drugs to aid in the regulation of aberrant alcohol consumption.
journal_name
Drug Alcohol Revjournal_title
Drug and alcohol reviewauthors
Lawrence AJdoi
10.1080/09595230601036937subject
Has Abstractpub_date
2007-01-01 00:00:00pages
3-8issue
1eissn
0959-5236issn
1465-3362pii
769825974journal_volume
26pub_type
杂志文章,评审abstract::The objective of this study was to examine patterns and yearly trends in alcohol-related hospitalization rates during the period 1987/88-1995/96 for men and women living in metropolitan and rural/remote Victoria. Alcohol-related hospitalizations were extracted from the Victorian Inpatient Minimum Dataset (VMD) for the...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/713659421
更新日期:2000-12-01 00:00:00
abstract:INTRODUCTION AND AIMS:Novel ways of accessing and engaging smokers who are socially and economically disadvantaged may help reduce socioeconomic disparities in smoking rates. This study assessed the feasibility and acceptability of integrating smoking cessation support into usual care at a social and community service ...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/j.1465-3362.2011.00391.x
更新日期:2012-07-01 00:00:00
abstract::The purpose of this study was to examine whether methadone maintenance treatment reduces injecting risk behaviour (and therefore transmission of blood-borne viral infections) among prisoners in New South Wales (NSW), using comparison of retrospective reports of drug use in prisons for people who received standard drug...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/09595239800186951
更新日期:1998-06-01 00:00:00
abstract::The development of policies in relation to unsupervised doses of methadone (take-away doses) should be based upon the best available evidence. There are both risks and benefits associated with take-away doses. This study aimed to explore the relationship between take-away policies and one measure of harm: methadone in...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/09595230500263939
更新日期:2005-07-01 00:00:00
abstract:INTRODUCTION AND AIMS:This paper explores excessive appetites, addiction and rehabilitation as described in the autobiographies, memoirs and diaries of rock artists. DESIGN AND METHODS:The data collection focused on autobiographical rock books written in English by internationally recognised rock artists before 2011. ...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/j.1465-3362.2012.00474.x
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION AND AIMS:Following the introduction of smoke-free policies in prisons in several countries, there have been anecdotal reports of prisoners creating cigarettes by mixing nicotine patches or lozenges with tea leaves ('teabacco'). Among a sample of people recently released from smoke-free prisons in Queenslan...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/dar.12848
更新日期:2018-11-01 00:00:00
abstract:INTRODUCTION AND AIMS:Needle and syringe program (NSP) workers have highlighted that people who inject image and performance enhancing drugs (IPED) in Australia are a younger and more culturally and linguistically diverse (CALD) group compared with other groups who inject drugs. Previous research has found riskier inje...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/dar.12467
更新日期:2017-09-01 00:00:00
abstract::This paper reports on the evaluation of the implementation of the National Recommendations for the Clinical Management of Alcohol-Related Problems in Indigenous Primary Care Settings undertaken in 2001 through 74 standardized workshops, which sought to determine: (1) whether this approach to implementation influenced ...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/09595230410001645583
更新日期:2004-03-01 00:00:00
abstract:INTRODUCTION AND AIMS:The aims of this study were to examine the roles of parental permissiveness toward alcohol use and affiliation with alcohol-using peers in alcohol use in youths from various ethnic backgrounds, and whether the role of peers was moderated by parental permissiveness. In addition, differences in thes...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/dar.12555
更新日期:2017-11-01 00:00:00
abstract:INTRODUCTION AND AIMS:Online gambling advertising and user-generated gambling content have increased. This study used a social psychological online experiment to analyse young people's reactions towards and self-reported interests in social media gambling messages. DESIGN AND METHODS:A vignette experiment with a two-l...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/dar.13010
更新日期:2020-02-01 00:00:00
abstract:INTRODUCTION AND AIMS:Alcohol rapidly reduces thiamine among alcohol-dependent individuals. Poor diet and alcohol's impact on absorption, storage, activation and excretion of thiamine are thought to be the mechanisms. Previous literature identifies magnesium as an important cofactor in thiamine utilisation, which might...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/dar.12237
更新日期:2015-05-01 00:00:00
abstract::To examine the extent to which hotel patrons drink in excess of current health recommendations, and to identify risk factors for excessive drinking, hotel patrons were invited to participate in a survey of social drinking, which included a free breath test. Patrons were approached at 15 min. intervals, and 1000 subjec...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/09595239300185711
更新日期:1993-01-01 00:00:00
abstract::The decision to drink and drive may involve the subjective process of weighing the perceived risks of adverse consequences of the behaviour against perceived utility components. Deterrence theory proposes that an individual will refrain from drink-driving if the perceived chances of experiencing negative outcomes asso...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/09595239600185651
更新日期:1996-03-01 00:00:00
abstract::The issues involved in teaching about drug and alcohol issues in medical schools incorporate a wide range of concerns. Any attempt to raise the proficiency of doctors in dealing with drug and alcohol problems must begin during their basic training, and impart the skills to continue learning after graduation. The princ...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/09595239100185071
更新日期:1991-01-01 00:00:00
abstract:INTRODUCTION AND AIMS:Alcohol use during adolescence is associated with the onset of alcohol use disorders, mental health disorders, substance abuse as well as socially and physically damaging behaviours, the effects of which last well into adulthood. Nevertheless, alcohol use remains prevalent in this population. Unde...
journal_title:Drug and alcohol review
pub_type: 杂志文章,随机对照试验
doi:10.1111/dar.12034
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION AND AIMS:The current study documents the characteristics associated with the use of two novel psychoactive substances: synthetic cannabinoids and synthetic cathinones. DESIGN AND METHODS:Nationally representative samples of students in 8th (n = 9665), 10th (n = 10 655) and 12th (n = 10 057) grades across ...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/dar.12372
更新日期:2016-09-01 00:00:00
abstract::With naltrexone registered only recently in Australia in 1999, it is important to examine the rate of uptake of naltrexone treatment, early attrition and retention rates during treatment, in order to inform the way naltrexone is used in Australian practice. Of 317 people screened for the study, 97 participants were re...
journal_title:Drug and alcohol review
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/09595230412331289464
更新日期:2004-09-01 00:00:00
abstract::Drug and alcohol agencies across Australia were asked to describe the services they offer to opiate users. Of the 284 agencies identified as providing treatment, 229 (81%) responded. A standard assessment procedure was used in 72% of agencies. Eighty (35%) agencies offered detoxification and had assisted 7883 clients ...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/09595239200185471
更新日期:1992-01-01 00:00:00
abstract::Studies of the processes by which people give up dependent heroin use are useful in helping services evaluate their treatment practices and in informing drug policy debates. In this exploratory investigation, a diverse group of 18 Canberra-based ex-users was interviewed about stopping, the role of treatment and their ...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/09595239400185381
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION AND AIMS:Impulsivity may be a risk factor that increases vulnerability to nicotine dependence. However, nicotine exposure itself may directly increase impulsivity. This is a secondary analysis of the first study in a controlled laboratory setting, which assessed the effects of nicotine administration (acut...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/dar.13206
更新日期:2020-11-02 00:00:00
abstract:INTRODUCTION:The aim of this paper is to describe the context of alcohol use and problems in Latin America and the Caribbean (LAC), the environmental context for alcohol-related policy, drinking trends, harm and policy and to systematically review policies implemented to reduce alcohol-related burden. METHODS:LAC-base...
journal_title:Drug and alcohol review
pub_type: 杂志文章,评审
doi:10.1111/dar.13227
更新日期:2021-01-24 00:00:00
abstract::Demographic, drug use and criminal correlates of risky drug practices were examined among 279 detained youth in NSW Juvenile Justice Centres. Binge drinking was common, with 63% reporting the consumption of at least five drinks in a row in the 2 weeks prior to incarceration. It was associated with being older, being f...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/09595239700186431
更新日期:1997-06-01 00:00:00
abstract::The central theme of the National Drug Strategy is "building partnerships". In the education and training arena, intersectoral partnerships are important to increase the skill and knowledge base of generic professionals. However, partnerships are neither simple nor straightforward endeavours. While this paper argues t...
journal_title:Drug and alcohol review
pub_type: 杂志文章,评审
doi:10.1080/0959523021000002651
更新日期:2002-09-01 00:00:00
abstract:INTRODUCTION AND AIMS:Problematic drinking and executive functioning deficits are two known risk factors for intimate partner aggression (IPA). However, executive functioning is a multifaceted construct, and it is not clear whether deficits in specific components of executive functioning are differentially associated w...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/dar.12454
更新日期:2017-01-01 00:00:00
abstract::Windows of opportunity for changing drug laws open infrequently and they often close without legislative change being affected. In this paper the author, who has been intimately involved in the process, describes how evidence-based recommendations to 'decriminalize' cannabis have recently been progressed through publi...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/09595230410001704226
更新日期:2004-06-01 00:00:00
abstract:INTRODUCTION AND AIMS:Studies link socio-economic deprivation to alcohol consumption in adolescents, but the role of relative deprivation has been understudied and may be equally important. This study investigates the association between relative deprivation and episodes of drunkenness among adolescents in France and C...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/dar.12540
更新日期:2017-11-01 00:00:00
abstract:ISSUES:Drug use accounts for one of the main disease groups in Europe, with relevant consequences to society. There is an increasing need to evaluate the economic consequences of drug use in order to develop appropriate policies. Here, we review the social costs of illegal drugs, alcohol and tobacco in the European Uni...
journal_title:Drug and alcohol review
pub_type: 杂志文章,评审
doi:10.1111/dar.12504
更新日期:2017-09-01 00:00:00
abstract::This study examined the prevalence and predictors of smoking by pregnant women attending a public antenatal clinic. The prevalence of smoking in this population (n = 2577) was found to be 38.0% (95% CI 36.1-39.9%). A review of previous research investigating variables associated with smoking in pregnancy indicated tha...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1080/09595239700186321
更新日期:1997-03-01 00:00:00
abstract:INTRODUCTION:Harms from intimate partners' (IP) drinking range from frustration because the partner has not performed their role to assault. AIM:To describe the prevalence and persistence of alcohol-related harms to IPs and assess which respondents are more likely to report discontinuation of this harm. DESIGN AND ME...
journal_title:Drug and alcohol review
pub_type: 杂志文章
doi:10.1111/dar.12435
更新日期:2017-01-01 00:00:00
abstract::The internet can provide wide access to online smoking cessation programmes developed by highly qualified professionals. Compared with one-to-one counselling in smoking cessation clinics or on telephone quitlines, the mass-level dissemination of automatised, individualised counselling on the internet is comparable to ...
journal_title:Drug and alcohol review
pub_type: 杂志文章,评审
doi:10.1080/09595230500459545
更新日期:2006-01-01 00:00:00