Therapeutics for alcoholism: what's the future?

Abstract:

:As with other addictions, human alcoholism is characterised as a chronically relapsing condition. Consequently, the therapeutic goal is the development of clinically effective, safe drugs that promote high adherence rates and prevent relapse. These products can then be used in conjunction with psychosocial approaches. In this review, preclinical studies are highlighted that indicate the mechanism of action of currently used anti-craving medications or demonstrate the potential of novel pharmacological agents for the treatment of alcohol use disorders. While current pharmacological strategies are far from ideal, there are a number of candidate molecules that may ultimately be developed into therapeutic agents. In addition, prescribing clinicians should also consider strategies such as combinations of various drugs to aid in the regulation of aberrant alcohol consumption.

journal_name

Drug Alcohol Rev

journal_title

Drug and alcohol review

authors

Lawrence AJ

doi

10.1080/09595230601036937

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

3-8

issue

1

eissn

0959-5236

issn

1465-3362

pii

769825974

journal_volume

26

pub_type

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