Polymyositis in a patient with recurring ovarian cancer and history of unrelated breast cancer.

Abstract:

BACKGROUND:Polymyositis (PM) is an idiopathic inflammatory myopathy. Occasionally, it may present as a paraneoplastic syndrome and it is strongly associated with ovarian and weakly with breast cancer. We present here a case of a 60-year-old patient with sequential breast and ovarian (second primary) carcinomas followed by PM as a paraneoplastic disorder. CASE REPORT:The patient had been diagnosed with stage I breast carcinoma 3 years ago and had been treated with conservative surgery followed by radiotherapy and six cycles of chemotherapy (CMF). One and a half year later an ovarian carcinoma was diagnosed for which the patient underwent abdominal hysterectomy oophorectomy and omentectomy. The pathological report characterized it as second primary. Adjuvant chemotherapy with carboplatin and taxol was administered. Fourteen months after the initial laparotomy, the patient was re-operated due to ovarian carcinoma recurrence which was involving all lesser pelvis organs. After a successful radical removal of the recurrence the patient developed a fully expressed PM. This case serves to remind that this disease can occur as a paraneoplastic disorder.

journal_name

Arch Gynecol Obstet

authors

Iavazzo C,Vorgias G,Papadakis M,Manikis P,Mavromatis I,Akrivos T

doi

10.1007/s00404-006-0307-z

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

81-4

issue

1

eissn

0932-0067

issn

1432-0711

journal_volume

276

pub_type

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