Abstract:
BACKGROUND:Polymyositis (PM) is an idiopathic inflammatory myopathy. Occasionally, it may present as a paraneoplastic syndrome and it is strongly associated with ovarian and weakly with breast cancer. We present here a case of a 60-year-old patient with sequential breast and ovarian (second primary) carcinomas followed by PM as a paraneoplastic disorder. CASE REPORT:The patient had been diagnosed with stage I breast carcinoma 3 years ago and had been treated with conservative surgery followed by radiotherapy and six cycles of chemotherapy (CMF). One and a half year later an ovarian carcinoma was diagnosed for which the patient underwent abdominal hysterectomy oophorectomy and omentectomy. The pathological report characterized it as second primary. Adjuvant chemotherapy with carboplatin and taxol was administered. Fourteen months after the initial laparotomy, the patient was re-operated due to ovarian carcinoma recurrence which was involving all lesser pelvis organs. After a successful radical removal of the recurrence the patient developed a fully expressed PM. This case serves to remind that this disease can occur as a paraneoplastic disorder.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Iavazzo C,Vorgias G,Papadakis M,Manikis P,Mavromatis I,Akrivos Tdoi
10.1007/s00404-006-0307-zsubject
Has Abstractpub_date
2007-07-01 00:00:00pages
81-4issue
1eissn
0932-0067issn
1432-0711journal_volume
276pub_type
杂志文章abstract::A well-circumscribed mass was excised from the vulva of a 37-year-old woman. Histological and immunohistochemical findings showed the characteristic features of fibroadenoma of breast. The concepts about the histogenesis of this lesion were discussed. ...
journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,meta分析
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pub_type: 新闻
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journal_title:Archives of gynecology and obstetrics
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