Abstract:
:The relatively new study of ribosomal proteins has allowed for greater understanding of protein synthesis; however the connection between ribosomal proteins' roles and that of disease pathophysiology has not yet been established. RPS19 is a ribosomal protein linked to Diamond-Blackfan anemia whose functions have begun to be elucidated. We review here the known roles of RPS19 in both ribosome construction and other extra-ribosomal functions and discuss their relationship to Diamond-Blackfan anemia.
journal_name
Mol Genet Metabjournal_title
Molecular genetics and metabolismauthors
Morimoto K,Lin S,Sakamoto Kdoi
10.1016/j.ymgme.2006.11.004subject
Has Abstractpub_date
2007-04-01 00:00:00pages
358-62issue
4eissn
1096-7192issn
1096-7206pii
S1096-7192(06)00362-3journal_volume
90pub_type
杂志文章,评审abstract::The diagnosis of bacterial infections can be difficult and time consuming. Rapid and reliable molecular triage of potentially infected patients, particularly the young and the elderly, would prevent unnecessary hospitalizations, reduce associated medical costs, and improve the quality of care. Polymerase chain reactio...
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journal_title:Molecular genetics and metabolism
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journal_title:Molecular genetics and metabolism
pub_type: 杂志文章
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journal_title:Molecular genetics and metabolism
pub_type: 杂志文章
doi:10.1016/j.ymgme.2011.07.023
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pub_type: 杂志文章,评审
doi:10.1006/mgme.2001.3207
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journal_title:Molecular genetics and metabolism
pub_type: 杂志文章
doi:10.1016/j.ymgme.2006.05.004
更新日期:2006-11-01 00:00:00
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journal_title:Molecular genetics and metabolism
pub_type: 杂志文章
doi:10.1016/j.ymgme.2007.06.016
更新日期:2007-09-01 00:00:00
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journal_title:Molecular genetics and metabolism
pub_type: 杂志文章
doi:10.1006/mgme.1999.2872
更新日期:1999-08-01 00:00:00
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journal_title:Molecular genetics and metabolism
pub_type: 杂志文章
doi:10.1016/j.ymgme.2007.03.009
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journal_title:Molecular genetics and metabolism
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pub_type: 杂志文章
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journal_title:Molecular genetics and metabolism
pub_type: 杂志文章
doi:10.1016/j.ymgme.2009.03.006
更新日期:2009-07-01 00:00:00
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journal_title:Molecular genetics and metabolism
pub_type: 杂志文章
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更新日期:2007-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-11-01 00:00:00
abstract::MPS IIIA is a lysosomal storage disorder caused by mutations in the sulphamidase gene, resulting in the accumulation of heparan sulphate glycosaminoglycans (HS GAGs). Symptoms predominantly manifest in the CNS and there is no current therapy that effectively addresses neuropathology in MPS IIIA patients. Recent studie...
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journal_title:Molecular genetics and metabolism
pub_type: 杂志文章
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更新日期:2017-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2021-01-14 00:00:00
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journal_title:Molecular genetics and metabolism
pub_type: 杂志文章
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journal_title:Molecular genetics and metabolism
pub_type: 杂志文章
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更新日期:1998-10-01 00:00:00